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Modeling DNA & RNA mutation using mset and topology
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作者 m. m. El-sharkasy m. s. badr 《International Journal of Biomathematics》 SCIE 2018年第4期257-270,共14页
Mathematical equations are now found not only in the books, but also they help in finding solutions for the biological problems by explaining the technicality of the current biological models and providing predictions... Mathematical equations are now found not only in the books, but also they help in finding solutions for the biological problems by explaining the technicality of the current biological models and providing predictions that can be validated and complemented to experimental and clinical studies. In this research paper, we use the mset theory to study DNA &: RNA mutations to discover the mutation occurrence. Also, we use the link between the concept of the meet and topology to determine the compatibility or similarity between "types", which may be the strings of bits, vectors, DNA or RNA sequences, etc. 展开更多
关键词 MUTATION DNA and RNA SIMILARITY mset topology.
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Topological spaces via phenotype--genotype spaces 被引量:1
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作者 m. m. EI-sharkasy m. s. badr 《International Journal of Biomathematics》 2016年第4期81-96,共16页
Researchers hope that establishing a notion of proximity using topology will help to clarify the biological processes underlying the evolution of living organisms. The simple model presented here, using RNA shapes, ca... Researchers hope that establishing a notion of proximity using topology will help to clarify the biological processes underlying the evolution of living organisms. The simple model presented here, using RNA shapes, can carry over to more general and complex genotype-phenotype systems. Proximity is an important component of continuity, in both real-world and topological terms. Consequently, phenotype spaces provide an appropriate setting for modeling and investigating continuous and discontinuous evolutionary change. 展开更多
关键词 RNA shapes PHENOTYPE TOPOLOGY genotype.
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