In the present study, the Pulsed Laser Deposition (PLD) technique was applied to coat titanium for orthopaedicand dental implant applications. Calcium carbonate (CC) was used as starting coating material.The deposited...In the present study, the Pulsed Laser Deposition (PLD) technique was applied to coat titanium for orthopaedicand dental implant applications. Calcium carbonate (CC) was used as starting coating material.The deposited CC films were transformed into octacalcium phosphate (OCP) by chemical treatments. Theresults of X-ray diffraction (XRD), Raman, Fourier Transform Infrared Spectroscopy (FTIR) and scanningelectron microscopy (SEM) studies revealed that the final OCP thin films are formed on the titaniumsurface. Human myofibroblasts from peripheral vessels and the primary bone marrow mesenchymalstromal cells (BMMSs) were cultured on the investigated materials. It was shown that all the investigatedsamples had no short-term toxic effects on cells. The rate of division of myofibroblast cells growing onthe surface and saturated BMMSs concentration for the OCP coating were about two times faster than ofcells growing on the CC films.展开更多
基金This work was supported by the Russian Science Foundation(project N15-19-00078)Authors are grateful to Mr.M.Ortenzi,G.De Santis and G.Emma for technical support and assistance.
文摘In the present study, the Pulsed Laser Deposition (PLD) technique was applied to coat titanium for orthopaedicand dental implant applications. Calcium carbonate (CC) was used as starting coating material.The deposited CC films were transformed into octacalcium phosphate (OCP) by chemical treatments. Theresults of X-ray diffraction (XRD), Raman, Fourier Transform Infrared Spectroscopy (FTIR) and scanningelectron microscopy (SEM) studies revealed that the final OCP thin films are formed on the titaniumsurface. Human myofibroblasts from peripheral vessels and the primary bone marrow mesenchymalstromal cells (BMMSs) were cultured on the investigated materials. It was shown that all the investigatedsamples had no short-term toxic effects on cells. The rate of division of myofibroblast cells growing onthe surface and saturated BMMSs concentration for the OCP coating were about two times faster than ofcells growing on the CC films.
