In a recent article in Science,Horowitz et al.identify glycosylphosphatidylinositol(GPI)-degrading enzyme Gpld1 as the most critical player in the blood that can transfer the effects of exercise on adult neurogenesis ...In a recent article in Science,Horowitz et al.identify glycosylphosphatidylinositol(GPI)-degrading enzyme Gpld1 as the most critical player in the blood that can transfer the effects of exercise on adult neurogenesis and cognition to sedentary aged mice.They also demonstrate the importance of this liver-to-brain axis in ameliorating age-related regenerative and cognitive impairments.展开更多
基金supported by the following:the Spanish Ministry of Economy and Competitiveness(SAF-2017-82185-R and RYC-2015-171899)The Alzheimer’s Association(AARG-17-528125).
文摘In a recent article in Science,Horowitz et al.identify glycosylphosphatidylinositol(GPI)-degrading enzyme Gpld1 as the most critical player in the blood that can transfer the effects of exercise on adult neurogenesis and cognition to sedentary aged mice.They also demonstrate the importance of this liver-to-brain axis in ameliorating age-related regenerative and cognitive impairments.
