目的通过文献计量学和可视化分析研究重症新型冠状病毒肺炎前沿问题。方法检索Web of Science数据库中2020年1月至2020年11月发表的重症新型冠状病毒肺炎文献,应用Excel和Cite Space软件进行文献计量分析和可视化分析。结果共纳入1176...目的通过文献计量学和可视化分析研究重症新型冠状病毒肺炎前沿问题。方法检索Web of Science数据库中2020年1月至2020年11月发表的重症新型冠状病毒肺炎文献,应用Excel和Cite Space软件进行文献计量分析和可视化分析。结果共纳入1176篇文献,从国家/地区、期刊、机构发文量进行计量学分析可知,美国和中国对重症新型冠状病毒肺炎的研究最为广泛,研究机构以高校居多,Critical Care期刊发文量最多。从作者合作、关键词共现和聚类、文献共被引进行文献可视化分析可知,本国不同作者间的合作关系密切,同一机构的不同作者更易形成合作关系,但是国际合作较少。该研究领域关注的热点为重症患者、临床表现、实验室检查和治疗,而且高被引文献关注的焦点与关键词方向一致。结论当前重症新型冠状病毒肺炎的临床表现、诊断、治疗是人们关注的热点,医务工作者应深化国际间合作,为未来的研究提供有力的参考依据。展开更多
目前在重症加强治疗病房(intensive care unit,ICU)超过60%的患者需要气管插管^([1]),同时作为一种高风险侵入性治疗方式,对于部分疾病引起的生理性气道困难,或因肥胖和怀孕等导致的解剖困难,可导致插管困难或不及时,插管过程中易发生...目前在重症加强治疗病房(intensive care unit,ICU)超过60%的患者需要气管插管^([1]),同时作为一种高风险侵入性治疗方式,对于部分疾病引起的生理性气道困难,或因肥胖和怀孕等导致的解剖困难,可导致插管困难或不及时,插管过程中易发生低氧血症、血流动力学不稳定、凝血障碍、呼吸机相关性肺炎等,严重时可导致心搏骤停^([2-3])。展开更多
Background Non-cement femoral stems are recognized in clinical use, but there are still some problems. The aim of this research was to make non-cement femoral stems to be press-fit with the medullary cavity. Methods T...Background Non-cement femoral stems are recognized in clinical use, but there are still some problems. The aim of this research was to make non-cement femoral stems to be press-fit with the medullary cavity. Methods Twenty-four healthy adult mongrel dogs were randomly divided into experimental and control groups. In the right hip joint, an artificial femoral bone replacement surgery was conducted. For the experimental group, the replacement surgery of hydroxyapatite （HA）-coated femoral stems was done, while autogeneous morselized bone was implanted into the medullary cavity. For the control group, morselized bone was not implanted. At postoperative 1, 3, 6 months, a test for interfacial shear characteristics was conducted in the MTS810 Tester. The comparison between the two groups＇ bone-prostheses in shear strength for their interface from shearing destruction was made. A histological observation to check prosthesis-bone interface contact ratios and bone growth was carried out. Results For the experimental group, shear strength was 0.317 MPa in 1 month, 1.447 MPa in 3 months, and 1.621 MPa in 6 months. For the control group, shear strength was 0.195 MPa in 1 month, 1.023 MPa in 3 months, and 1.483 MPa in 6 months. The difference was statistically significant. Stereomicroscope-based observation showed that the number of trabecular bones in the experimental group was larger than that of the control group, and bone growth of the former group was better than that of the latter group. Inverted microscopic observation showed that the binding degree between the prosthesis and trabecular bone of the experimental group was higher than that of the control group. Comparatively, the experimental group＇s trabecular bone had more stromal cells. Conclusions The morselized bones can effectively improve the biological bonding strength and bone-contact ratios in the short term for the HA-coated femoral stem and accelerate the bonding process. The use of morselized autogenous bones played a good role in bone in-growth of the femoral bone stem surface.展开更多
文摘目的通过文献计量学和可视化分析研究重症新型冠状病毒肺炎前沿问题。方法检索Web of Science数据库中2020年1月至2020年11月发表的重症新型冠状病毒肺炎文献,应用Excel和Cite Space软件进行文献计量分析和可视化分析。结果共纳入1176篇文献,从国家/地区、期刊、机构发文量进行计量学分析可知,美国和中国对重症新型冠状病毒肺炎的研究最为广泛,研究机构以高校居多,Critical Care期刊发文量最多。从作者合作、关键词共现和聚类、文献共被引进行文献可视化分析可知,本国不同作者间的合作关系密切,同一机构的不同作者更易形成合作关系,但是国际合作较少。该研究领域关注的热点为重症患者、临床表现、实验室检查和治疗,而且高被引文献关注的焦点与关键词方向一致。结论当前重症新型冠状病毒肺炎的临床表现、诊断、治疗是人们关注的热点,医务工作者应深化国际间合作,为未来的研究提供有力的参考依据。
文摘目前在重症加强治疗病房(intensive care unit,ICU)超过60%的患者需要气管插管^([1]),同时作为一种高风险侵入性治疗方式,对于部分疾病引起的生理性气道困难,或因肥胖和怀孕等导致的解剖困难,可导致插管困难或不及时,插管过程中易发生低氧血症、血流动力学不稳定、凝血障碍、呼吸机相关性肺炎等,严重时可导致心搏骤停^([2-3])。
文摘Background Non-cement femoral stems are recognized in clinical use, but there are still some problems. The aim of this research was to make non-cement femoral stems to be press-fit with the medullary cavity. Methods Twenty-four healthy adult mongrel dogs were randomly divided into experimental and control groups. In the right hip joint, an artificial femoral bone replacement surgery was conducted. For the experimental group, the replacement surgery of hydroxyapatite （HA）-coated femoral stems was done, while autogeneous morselized bone was implanted into the medullary cavity. For the control group, morselized bone was not implanted. At postoperative 1, 3, 6 months, a test for interfacial shear characteristics was conducted in the MTS810 Tester. The comparison between the two groups＇ bone-prostheses in shear strength for their interface from shearing destruction was made. A histological observation to check prosthesis-bone interface contact ratios and bone growth was carried out. Results For the experimental group, shear strength was 0.317 MPa in 1 month, 1.447 MPa in 3 months, and 1.621 MPa in 6 months. For the control group, shear strength was 0.195 MPa in 1 month, 1.023 MPa in 3 months, and 1.483 MPa in 6 months. The difference was statistically significant. Stereomicroscope-based observation showed that the number of trabecular bones in the experimental group was larger than that of the control group, and bone growth of the former group was better than that of the latter group. Inverted microscopic observation showed that the binding degree between the prosthesis and trabecular bone of the experimental group was higher than that of the control group. Comparatively, the experimental group＇s trabecular bone had more stromal cells. Conclusions The morselized bones can effectively improve the biological bonding strength and bone-contact ratios in the short term for the HA-coated femoral stem and accelerate the bonding process. The use of morselized autogenous bones played a good role in bone in-growth of the femoral bone stem surface.
