In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam ...In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam collimator. The sensitivity of the single photon emission computed tomography (SPECT) system is improved by allowing projection overlapping. Comparative simulation studies were performed in the MPB collimators, general purpose parallel-beam (GPPB) collimators and high sensitivity parallel-beam (HSPB) collimators. In the simulation, attenuation, scattering and the impact of detector response were neglected. Simulation results show that the sensitivity is improved for the MPB collimator comparing with parallel-beam collimator. The behavior of spatial resolution is only different near the front face of the collimators and approaches that of the GPPB with increasing depth. Proper pre-filtering is helpful for the image reconstruction in the MPB collimators. Comparing with the HSPB collimator, the MPB can achieve a similar sensitivity and better resolution. The simulation ot the U87 cells, and their expression levels were higher in the 10 Gy group than in the 0 Gy group. The differential gene expression in DCX-U87 cells before and after radiation is helpful for future investigations into the mechanisms of radiation therapy in neurogliocytoma cells.展开更多
为进一步提升综合能源系统环境效益,减少新能源出力不确定性所带来的潜在风险,提出了计及条件风险价值(conditional value at risk,CVaR)以及阶梯碳交易的综合能源系统优化调度模型。考虑到系统风电和光伏出力不确定性可能带来的影响,...为进一步提升综合能源系统环境效益,减少新能源出力不确定性所带来的潜在风险,提出了计及条件风险价值(conditional value at risk,CVaR)以及阶梯碳交易的综合能源系统优化调度模型。考虑到系统风电和光伏出力不确定性可能带来的影响,采用条件风险价值量度不确定性带来的潜在风险,并将碳捕获技术、电转气设备以及阶梯式碳交易机制引入系统调度模型,构建了综合考虑系统运行成本和碳交易成本的优化调度目标函数,由于所建立模型为混合整数规划问题,采用CPLEX求解器进行求解,设置4种场景进行验证分析,算例表明所提模型可有效减少二氧化碳排放,在兼顾经济性和环境性的同时引入CVaR,可避免由于忽略风光不确定性所带来的较为乐观的调度结果,使系统最终调度结果更为合理。展开更多
Methylene blue(MB)was reported to have neuronal protective effect after brain ischermia.In this study,we aimed to investigate the effect of MB on white matter in rats after focal cerebral ischemia-reperfusion(MCAO/R)i...Methylene blue(MB)was reported to have neuronal protective effect after brain ischermia.In this study,we aimed to investigate the effect of MB on white matter in rats after focal cerebral ischemia-reperfusion(MCAO/R)injury.MCAO/R model was set and 54 male SD rats were randomly divided into 3 groups:control(sham surgery group),middle cerebral artery occlusion and reperfusion(MCAO),MCAO treated with MB of 10 mg/kg(MB)by intraperitoneal injection 1.5 h after surgery.We observed the neurological deficits in different groups using foot fault test 24 h after MCAO.We measured the infarction volume using TTC staining and showed the morphological changes of neurons and myelin using Nissl and black gold staining.展开更多
基金Supported by the Priority Academic Program Development of Jiangsu College Education
文摘In this paper, a new design of multi-parallel-beam (MPB) collimators with projection multiplexing is proposed. In the MPB system, two different oblique parallel channels are introduced in a conventional parallel-beam collimator. The sensitivity of the single photon emission computed tomography (SPECT) system is improved by allowing projection overlapping. Comparative simulation studies were performed in the MPB collimators, general purpose parallel-beam (GPPB) collimators and high sensitivity parallel-beam (HSPB) collimators. In the simulation, attenuation, scattering and the impact of detector response were neglected. Simulation results show that the sensitivity is improved for the MPB collimator comparing with parallel-beam collimator. The behavior of spatial resolution is only different near the front face of the collimators and approaches that of the GPPB with increasing depth. Proper pre-filtering is helpful for the image reconstruction in the MPB collimators. Comparing with the HSPB collimator, the MPB can achieve a similar sensitivity and better resolution. The simulation ot the U87 cells, and their expression levels were higher in the 10 Gy group than in the 0 Gy group. The differential gene expression in DCX-U87 cells before and after radiation is helpful for future investigations into the mechanisms of radiation therapy in neurogliocytoma cells.
文摘为进一步提升综合能源系统环境效益,减少新能源出力不确定性所带来的潜在风险,提出了计及条件风险价值(conditional value at risk,CVaR)以及阶梯碳交易的综合能源系统优化调度模型。考虑到系统风电和光伏出力不确定性可能带来的影响,采用条件风险价值量度不确定性带来的潜在风险,并将碳捕获技术、电转气设备以及阶梯式碳交易机制引入系统调度模型,构建了综合考虑系统运行成本和碳交易成本的优化调度目标函数,由于所建立模型为混合整数规划问题,采用CPLEX求解器进行求解,设置4种场景进行验证分析,算例表明所提模型可有效减少二氧化碳排放,在兼顾经济性和环境性的同时引入CVaR,可避免由于忽略风光不确定性所带来的较为乐观的调度结果,使系统最终调度结果更为合理。
文摘Methylene blue(MB)was reported to have neuronal protective effect after brain ischermia.In this study,we aimed to investigate the effect of MB on white matter in rats after focal cerebral ischemia-reperfusion(MCAO/R)injury.MCAO/R model was set and 54 male SD rats were randomly divided into 3 groups:control(sham surgery group),middle cerebral artery occlusion and reperfusion(MCAO),MCAO treated with MB of 10 mg/kg(MB)by intraperitoneal injection 1.5 h after surgery.We observed the neurological deficits in different groups using foot fault test 24 h after MCAO.We measured the infarction volume using TTC staining and showed the morphological changes of neurons and myelin using Nissl and black gold staining.