The E^(rns)gene of five prevalent virulent strains and one C-strain of Hog Cholera Virus were amplified by reverse transcription(RT).The amplified fragments were cloned and sequenced.Comparison and analysis were made ...The E^(rns)gene of five prevalent virulent strains and one C-strain of Hog Cholera Virus were amplified by reverse transcription(RT).The amplified fragments were cloned and sequenced.Comparison and analysis were made on the nucleotide sequence and the amino acid sequence of five prevalent virulent strains of HCV was deduced.The nucleotide homology was from 91%to 98%;the homology of amino acid was from 94%to 98%.The nucleotide homology of C-strain virus from cell cultured and five prevalent virulent strains of HCV was 83%to 84%.The amino acid homology was from 89%to 91%.展开更多
目的观察小剂量右美托咪定镇静治疗对老年急性左心力衰竭患者无创正压通气(NPPV)的影响。方法120例需行无创正压通气的老年急性左心力衰竭患者作为研究对象,随机分为对照组(C组)、咪达唑仑组(M组)和右美托咪定组(D组),每组40例。分别记...目的观察小剂量右美托咪定镇静治疗对老年急性左心力衰竭患者无创正压通气(NPPV)的影响。方法120例需行无创正压通气的老年急性左心力衰竭患者作为研究对象,随机分为对照组(C组)、咪达唑仑组(M组)和右美托咪定组(D组),每组40例。分别记录各组患者的一般资料、心率(HR)、呼吸(RR)、平均动脉压(MAP)、氧合指数(OI)、NPPV时间、无创改有创通气率、谵妄发生率、病死率。结果各组患者的年龄、性别、体重、急性生理与慢性健康评分(APACHEⅡ)比较,差异均无统计学意义(均P>0.05)。各组患者上机前HR、RR差异均无统计学意义(均P>0.05)。与C组比较,M组和D组上机后30 min、上机后1 h、上机后2 h HR和RR降低,差异均有统计学意义(均P<0.05)。各组上机前、上机后30 min、上机后1 h、上机后2 h MAP差异无统计学意义(P>0.05)。各组上机前OI差异无统计学意义(P>0.05)。与C组比较,M组和D组上机后1h、上机后6h、上机后24h和上机后72 h OI升高,差异均有统计学意义(均P<0.05)。与C组比较,M组和D组NPPV时间缩短,差异有统计学意义(P<0.05)。各组病死率比较差异无统计学意义(均P>0.05)。与C和M组比较,D组谵妄发生率下降,差异有统计学意义(P<0.05)。结论右美托咪定和咪达唑仑镇静治疗能够提高老年急性左心力衰竭患者的无创呼吸正压通气氧合,缩短NPPV时间;且小剂量右美托咪定可以降低老年急性左心力衰竭患者的谵妄发生率。展开更多
文摘The E^(rns)gene of five prevalent virulent strains and one C-strain of Hog Cholera Virus were amplified by reverse transcription(RT).The amplified fragments were cloned and sequenced.Comparison and analysis were made on the nucleotide sequence and the amino acid sequence of five prevalent virulent strains of HCV was deduced.The nucleotide homology was from 91%to 98%;the homology of amino acid was from 94%to 98%.The nucleotide homology of C-strain virus from cell cultured and five prevalent virulent strains of HCV was 83%to 84%.The amino acid homology was from 89%to 91%.
文摘目的观察小剂量右美托咪定镇静治疗对老年急性左心力衰竭患者无创正压通气(NPPV)的影响。方法120例需行无创正压通气的老年急性左心力衰竭患者作为研究对象,随机分为对照组(C组)、咪达唑仑组(M组)和右美托咪定组(D组),每组40例。分别记录各组患者的一般资料、心率(HR)、呼吸(RR)、平均动脉压(MAP)、氧合指数(OI)、NPPV时间、无创改有创通气率、谵妄发生率、病死率。结果各组患者的年龄、性别、体重、急性生理与慢性健康评分(APACHEⅡ)比较,差异均无统计学意义(均P>0.05)。各组患者上机前HR、RR差异均无统计学意义(均P>0.05)。与C组比较,M组和D组上机后30 min、上机后1 h、上机后2 h HR和RR降低,差异均有统计学意义(均P<0.05)。各组上机前、上机后30 min、上机后1 h、上机后2 h MAP差异无统计学意义(P>0.05)。各组上机前OI差异无统计学意义(P>0.05)。与C组比较,M组和D组上机后1h、上机后6h、上机后24h和上机后72 h OI升高,差异均有统计学意义(均P<0.05)。与C组比较,M组和D组NPPV时间缩短,差异有统计学意义(P<0.05)。各组病死率比较差异无统计学意义(均P>0.05)。与C和M组比较,D组谵妄发生率下降,差异有统计学意义(P<0.05)。结论右美托咪定和咪达唑仑镇静治疗能够提高老年急性左心力衰竭患者的无创呼吸正压通气氧合,缩短NPPV时间;且小剂量右美托咪定可以降低老年急性左心力衰竭患者的谵妄发生率。