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慢性牙周炎患者外周血辅助性T细胞及牙周组织白细胞介素-17和干扰素-γ表达与感染机制的相关性研究
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作者 刘玮健 马威 +2 位作者 苑翔 马铭阳 张辉 《当代医学》 2023年第23期32-35,共4页
目的探讨慢性牙周炎患者外周血辅助性T细胞1(Th1)、辅助性T细胞2(Th2)、辅助性T细胞17(Th17)及牙周组织白细胞介素-17(IL-17)、干扰素-γ(IFN-γ)表达与感染机制的相关性。方法选取2019年10月至2021年1月本院收治的慢性牙周炎患者110例... 目的探讨慢性牙周炎患者外周血辅助性T细胞1(Th1)、辅助性T细胞2(Th2)、辅助性T细胞17(Th17)及牙周组织白细胞介素-17(IL-17)、干扰素-γ(IFN-γ)表达与感染机制的相关性。方法选取2019年10月至2021年1月本院收治的慢性牙周炎患者110例作为观察组,按照慢性牙周炎的严重程度分为重度组(n=49)与轻中度组(n=61),选取同期60名牙周健康者作为健康组,比较3组外周血Th1、Th2、Th17水平,分析牙周组织HE染色检测结果,比较观察组与健康组IL-17、IFN-γ细胞H-score评分。结果重度组、轻中度组外周血Th1、Th2、Th17水平均高于健康组,且重度组Th1、Th17水平高于轻中度组,差异有统计学意义(P<0.05)。轻度牙周炎患者淋巴细胞数目少于中、重度牙周炎患者,且中度牙周炎患者少于重度牙周炎患者,差异有统计学意义(P<0.05)。观察组牙周组织IL-17、IFN-γ细胞的H-score评分均高于健康组,差异有统计学意义(P<0.05)。结论慢性牙周炎患者外周血Th1、Th2、Th17及牙周组织IL-17、IFN-γ表达升高,与感染相关。 展开更多
关键词 慢性牙周炎 辅助性T细胞1 辅助性T细胞2 辅助性T细胞17 白细胞介素-17 干扰素-Γ
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He-Ar Isotopic Systematics of Fluid Inclusions in Pyrites from PGEpolymetallic Deposits in Lower Cambrian Black Rock Series, South China 被引量:16
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作者 SUNXiaoming WANGMin +2 位作者 XUETing mamingyang LIYinhe 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2004年第2期471-475,共5页
He-Ar isotopic compositions of fluid inclusions trapped in pyrites from some representative PGE-polymetallic deposits in Lower Cambrian black rock series in South China were analyzed by using an inert gas isotopic mas... He-Ar isotopic compositions of fluid inclusions trapped in pyrites from some representative PGE-polymetallic deposits in Lower Cambrian black rock series in South China were analyzed by using an inert gas isotopic mass spectrometer. The results show that the ore-forming fluids possess a low 3He/4He ratio, varying from 0.43×10-8 to 26.39×10-8, with corresponding R/Ra value of 0.003-0.189. The 40Ar/36Ar ratios are 258-287, close to those of air saturated water (ASW). He-Ar isotopic indicator studies show that the ore-forming fluids were mainly derived from the formation water or basinal hot brine and sea water, while the content of mantle-derived fluid or deep-derived magmatic water might be negligible. The PGE-polymetallic mineralization might be related to the evolution of the Caledonian miogeosynclines distributed along the southern margin of the Yangtze Craton. During the Early Cambrian, the formation water or basinal hot brine trapped in Caledonian basins which accumulated giant thick sediments was expelled and migrated laterally along strata because of the pressure generated by overlying sediments. The basinal hot brine ascended along faults, mixed with sea water and finally deposited ore minerals. 展开更多
关键词 He-Ar isotopic systematics pyrite fluid inclusions PGE-polymetallic deposit basinal hot brine
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