AIM: To assess the safety and feasibility of peroral esophageal myotomy(POEM) in patients with achalasia.METHODS: From January 2012 to March 2014, 50 patients(28 men, 22 women; mean age: 42.8 years, range: 14-70 years...AIM: To assess the safety and feasibility of peroral esophageal myotomy(POEM) in patients with achalasia.METHODS: From January 2012 to March 2014, 50 patients(28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt scoring system. Barium swallow and esophagogastroscopy were performed before and after POEM, respectively. Esophageal motility was evaluated in all patients, both preoperatively and one month after POEM treatment, using a high-resolution manometry system. Manometry data, Eckardt scores, lower esophageal sphincter pressure and barium swallow results were used to evaluate the effect of the procedure.RESULTS: POEM was successfully completed for all patients. The mean procedure time was 55.4 ± 17.3 min and the mean total length of myotomy of the circular esophagus was 10.5 ± 2.6 cm. No specific complications occurred, with the exception of two patients that developed as ymptomatic pneumomediastinum and subcutaneous emphysema. Clinical improvement in symptoms was achieved in all patients. Approximately 77.5% of patients experienced weight gain 6 mo after POEM, with an average of 4.78 kg(range: 2-15 kg). The lower esophageal sphincter resting pressure, four second integrated relaxation pressure and Eckardt scores were all significantly reduced after POEM(Ps < 0.05). A small segment of proximal esophageal peristalsis appeared postoperatively in two patients, but without normal esophageal peristalsis. The average diameter of the esophageal lumen decreased significantly from 4.39 to 3.09 cm(P < 0.01). CONCLUSION: POEM can relieve achalasia symptoms, improve gastroesophageal junction relaxation and restore esophageal body motility function, but not normal esophageal peristalsis.展开更多
A large number of seismic records are discovered for the first time in the historical materials about Wudalianchi volcanic group eruption in 1720~1721, which provides us with abundant volcanic earthquake information. ...A large number of seismic records are discovered for the first time in the historical materials about Wudalianchi volcanic group eruption in 1720~1721, which provides us with abundant volcanic earthquake information. Based on the written records, the relationship between earthquake and volcanic eruption is discussed in the paper. Fur-thermore it is pointed that earthquake swarm is an important indication of volcanic eruption. Therefore, monitoring volcanic earthquakes is of great significance for forecasting volcanic eruption.展开更多
Left ventricular hypertrophy associated with the use of tacrolimus is a rare complication of solid organ transplantation in adult recipients. We present a cardiac transplant recipient who developed severe concentric l...Left ventricular hypertrophy associated with the use of tacrolimus is a rare complication of solid organ transplantation in adult recipients. We present a cardiac transplant recipient who developed severe concentric left ventricular hypertrophy with congestive heart failure related to myocardial hypertrophy on tacrolimus. Hypertrophy improved when the drug was discontinued and replaced with sirolimus.展开更多
The Letter reports the thermal stability and strain response of Fabry–Perot(FP) cavity under different high temperatures. The FP cavity was made by thermal regeneration of two identical cascaded fiber Bragg gratings(...The Letter reports the thermal stability and strain response of Fabry–Perot(FP) cavity under different high temperatures. The FP cavity was made by thermal regeneration of two identical cascaded fiber Bragg gratings(FBGs). It is demonstrated that the FP cavity is capable of measuring temperatures from 300℃ to 900℃ with a temperature sensitivity of 15.97 pm/℃. The elongation of the fiber was observed through the drifted Bragg wavelength at 700℃ or above when weight was loaded. The elongation was further inferred by the slight change in the interference spectra of the FP cavity at 900℃.展开更多
文摘AIM: To assess the safety and feasibility of peroral esophageal myotomy(POEM) in patients with achalasia.METHODS: From January 2012 to March 2014, 50 patients(28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt scoring system. Barium swallow and esophagogastroscopy were performed before and after POEM, respectively. Esophageal motility was evaluated in all patients, both preoperatively and one month after POEM treatment, using a high-resolution manometry system. Manometry data, Eckardt scores, lower esophageal sphincter pressure and barium swallow results were used to evaluate the effect of the procedure.RESULTS: POEM was successfully completed for all patients. The mean procedure time was 55.4 ± 17.3 min and the mean total length of myotomy of the circular esophagus was 10.5 ± 2.6 cm. No specific complications occurred, with the exception of two patients that developed as ymptomatic pneumomediastinum and subcutaneous emphysema. Clinical improvement in symptoms was achieved in all patients. Approximately 77.5% of patients experienced weight gain 6 mo after POEM, with an average of 4.78 kg(range: 2-15 kg). The lower esophageal sphincter resting pressure, four second integrated relaxation pressure and Eckardt scores were all significantly reduced after POEM(Ps < 0.05). A small segment of proximal esophageal peristalsis appeared postoperatively in two patients, but without normal esophageal peristalsis. The average diameter of the esophageal lumen decreased significantly from 4.39 to 3.09 cm(P < 0.01). CONCLUSION: POEM can relieve achalasia symptoms, improve gastroesophageal junction relaxation and restore esophageal body motility function, but not normal esophageal peristalsis.
文摘A large number of seismic records are discovered for the first time in the historical materials about Wudalianchi volcanic group eruption in 1720~1721, which provides us with abundant volcanic earthquake information. Based on the written records, the relationship between earthquake and volcanic eruption is discussed in the paper. Fur-thermore it is pointed that earthquake swarm is an important indication of volcanic eruption. Therefore, monitoring volcanic earthquakes is of great significance for forecasting volcanic eruption.
文摘Left ventricular hypertrophy associated with the use of tacrolimus is a rare complication of solid organ transplantation in adult recipients. We present a cardiac transplant recipient who developed severe concentric left ventricular hypertrophy with congestive heart failure related to myocardial hypertrophy on tacrolimus. Hypertrophy improved when the drug was discontinued and replaced with sirolimus.
基金supported by the Program for Changjiang Scholars and Innovative Research Team in the University of Ministry of Education of China(No.IRT_16R07)the Importation and Development of High-Caliber Talents Project of Beijing Municipal Institutions(No.IDHT20170510)
文摘The Letter reports the thermal stability and strain response of Fabry–Perot(FP) cavity under different high temperatures. The FP cavity was made by thermal regeneration of two identical cascaded fiber Bragg gratings(FBGs). It is demonstrated that the FP cavity is capable of measuring temperatures from 300℃ to 900℃ with a temperature sensitivity of 15.97 pm/℃. The elongation of the fiber was observed through the drifted Bragg wavelength at 700℃ or above when weight was loaded. The elongation was further inferred by the slight change in the interference spectra of the FP cavity at 900℃.
