The effects of 14 factors on food production in Huang-Huai-Hai Plain are analyzed by path analysis in this paper,and then the linear regression models of them are established by SPSS software. The results show that el...The effects of 14 factors on food production in Huang-Huai-Hai Plain are analyzed by path analysis in this paper,and then the linear regression models of them are established by SPSS software. The results show that electricity consumption for agriculture,growing area of crops,the affected area,annual average temperature and arable land area at the end of the year have great effects on food production. Finally some recommendations are put forward to improve the food production in Huang-Huai-Hai Plain such as improving the level of agricultural mechanization,stabilizing food production,preventing natural disasters and increasing the effective irrigation area.展开更多
Vapor deposition and three-dimensional(3D)printing technology are considered to be conventional methods to achieve patterned metal film preparation through the assistance of masks and high temperature.Therefore,there ...Vapor deposition and three-dimensional(3D)printing technology are considered to be conventional methods to achieve patterned metal film preparation through the assistance of masks and high temperature.Therefore,there are still some challenges in fabricating metal films in template-free and normal temperature environment.In this work,we report a flexible and rapid laser metal transfer(LMT)technique for fabricating the various metal films(Cu,Ni,Sn,Al,Fe,and Ag)with different patterns without templates on arbitrary substrates(glass,polyimide(PI)films,and aluminum nitride(AlN)ceramic).Especially,the obtained transparent conductive glass displays high transmittance(more than 90%)and adjustable resistances(≈5Ω).According to the Joule effect,the interface resistance between Cu particles and copper oxide coating produces the high temperature approximately 280℃ at 2 V in a short time(≈60 s)and remains stable at 120℃ over 12 h.At last,the multifunctional glass with Cu patterns also shows excellent bactericidal activity(≈95%).This work demonstrates that laser metal transfer is an exceeding effective means of fabricating the micro/nano structures with potential applications in functional devices.展开更多
Natural molecular chaperones utilize spatially ordered multiple molecular forces to effectively regulate protein folding.However,synthesis of such molecules is a big challenge.The concept of“aggregate science”provid...Natural molecular chaperones utilize spatially ordered multiple molecular forces to effectively regulate protein folding.However,synthesis of such molecules is a big challenge.The concept of“aggregate science”provides insights to construct chemical entities(aggregates)beyond molecular levels to mimic both the structure and function of natural chaperone.Inspired by this concept,herein we fabricate a novel multi-interaction(i.e.,electrostatic and hydrophobic interaction)cooperative nanochaperone(multi-co-nChap)to regulating protein folding.This multi-co-nChap is fabricated by rationally introducing electrostatic interactions to the surface(corona)and confined hydrophobic microdomains(shell)of traditional single-hydrophobic interaction nanochaperone.We demonstrate that the corona electrostatic attraction facilitates the diffusion of clients into the hydrophobic microdomains,while the shell electrostatic interaction balances the capture and release of clients.By finely synergizing corona electrostatic attraction with shell electrostatic repulsion and hydrophobic interaction,the optimized multi-co-nChap effectively facilitated de novo folding of nascent polypeptides.Moreover,the synergy between corona electrostatic attraction,shell electrostatic attraction and shell hydrophobic interaction significantly enhanced the capability of multi-co-nChap to protect native proteins from denaturation at harsh temperatures.This work provides important insights for understanding and design of nanochaperone,which is a kind of ordered aggregate with chaperone-like activity that beyond the level of single molecule.展开更多
Laughter may be scarce in China’s disaster-ridden 2020,but artist Wang Qingsong,known for his staged photography sets and exaggerated themes,is more than up to the challenge with a solo exhibition that pokes fun at c...Laughter may be scarce in China’s disaster-ridden 2020,but artist Wang Qingsong,known for his staged photography sets and exaggerated themes,is more than up to the challenge with a solo exhibition that pokes fun at consumerism,technology...and himself.展开更多
基金Supported by Soft Science Project of Shandong Province(2009RKB01052)
文摘The effects of 14 factors on food production in Huang-Huai-Hai Plain are analyzed by path analysis in this paper,and then the linear regression models of them are established by SPSS software. The results show that electricity consumption for agriculture,growing area of crops,the affected area,annual average temperature and arable land area at the end of the year have great effects on food production. Finally some recommendations are put forward to improve the food production in Huang-Huai-Hai Plain such as improving the level of agricultural mechanization,stabilizing food production,preventing natural disasters and increasing the effective irrigation area.
基金supported by the Taishan Scholar Project of Shandong Province(No.tsqn201812083)the Natural Science Foundation of Shandong Province(Nos.ZR2021JQ15,ZR2020QE071,ZR2020LLZ006,and ZR2020MH191)+1 种基金the Innovative Team Project of Jinan(No.2021GXRC019)the National Natural Science Foundation of China(Nos.52022037,52102171,and 62174068).
文摘Vapor deposition and three-dimensional(3D)printing technology are considered to be conventional methods to achieve patterned metal film preparation through the assistance of masks and high temperature.Therefore,there are still some challenges in fabricating metal films in template-free and normal temperature environment.In this work,we report a flexible and rapid laser metal transfer(LMT)technique for fabricating the various metal films(Cu,Ni,Sn,Al,Fe,and Ag)with different patterns without templates on arbitrary substrates(glass,polyimide(PI)films,and aluminum nitride(AlN)ceramic).Especially,the obtained transparent conductive glass displays high transmittance(more than 90%)and adjustable resistances(≈5Ω).According to the Joule effect,the interface resistance between Cu particles and copper oxide coating produces the high temperature approximately 280℃ at 2 V in a short time(≈60 s)and remains stable at 120℃ over 12 h.At last,the multifunctional glass with Cu patterns also shows excellent bactericidal activity(≈95%).This work demonstrates that laser metal transfer is an exceeding effective means of fabricating the micro/nano structures with potential applications in functional devices.
基金National Natural Science Foundation of China,Grant/Award Numbers:51933006,52373153,52293383National Key Research and Development Program of China,Grant/Award Number:2022YFA1205702Haihe Laboratory of Sustainable Chemical Transformations,Grant/Award Number:YYJC202102。
文摘Natural molecular chaperones utilize spatially ordered multiple molecular forces to effectively regulate protein folding.However,synthesis of such molecules is a big challenge.The concept of“aggregate science”provides insights to construct chemical entities(aggregates)beyond molecular levels to mimic both the structure and function of natural chaperone.Inspired by this concept,herein we fabricate a novel multi-interaction(i.e.,electrostatic and hydrophobic interaction)cooperative nanochaperone(multi-co-nChap)to regulating protein folding.This multi-co-nChap is fabricated by rationally introducing electrostatic interactions to the surface(corona)and confined hydrophobic microdomains(shell)of traditional single-hydrophobic interaction nanochaperone.We demonstrate that the corona electrostatic attraction facilitates the diffusion of clients into the hydrophobic microdomains,while the shell electrostatic interaction balances the capture and release of clients.By finely synergizing corona electrostatic attraction with shell electrostatic repulsion and hydrophobic interaction,the optimized multi-co-nChap effectively facilitated de novo folding of nascent polypeptides.Moreover,the synergy between corona electrostatic attraction,shell electrostatic attraction and shell hydrophobic interaction significantly enhanced the capability of multi-co-nChap to protect native proteins from denaturation at harsh temperatures.This work provides important insights for understanding and design of nanochaperone,which is a kind of ordered aggregate with chaperone-like activity that beyond the level of single molecule.
文摘Laughter may be scarce in China’s disaster-ridden 2020,but artist Wang Qingsong,known for his staged photography sets and exaggerated themes,is more than up to the challenge with a solo exhibition that pokes fun at consumerism,technology...and himself.