HIV is a neurotropic virus and can be engulfed macrophagocytes. It invades the brain tissue via the blood-brain barrier and multiplies in the cerebrospinal fluid （CSF）. HIV has been isolated from the brain, spinal m...HIV is a neurotropic virus and can be engulfed macrophagocytes. It invades the brain tissue via the blood-brain barrier and multiplies in the cerebrospinal fluid （CSF）. HIV has been isolated from the brain, spinal marrow, peripheral nerve, and the CSF. Electronic microscopy, immunohistochemistry, and in situ hybridization have demonstrated monocytes and multinucleated cells containing HIV virus.展开更多
基金This work was supported by special funds of the National Serious Infectious Diseases Foundation of China （No. 2008ZX10001-006）, grants from Beijing Natural Science Foundation （No. 7132108）, and the Academic Leader of 215 High-level Health Personnel, Beijing, China （No. 2009-3-55）.
文摘HIV is a neurotropic virus and can be engulfed macrophagocytes. It invades the brain tissue via the blood-brain barrier and multiplies in the cerebrospinal fluid （CSF）. HIV has been isolated from the brain, spinal marrow, peripheral nerve, and the CSF. Electronic microscopy, immunohistochemistry, and in situ hybridization have demonstrated monocytes and multinucleated cells containing HIV virus.
