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Reversed-Phase High-Performance Liquid  Chromatographic Determination of Drugs of Abuse
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作者 ma, c Duan, HJ +1 位作者 Xu, YQ Zhou, TH 《Chinese Chemical Letters》 SCIE CAS CSCD 1996年第11期1027-1028,共2页
A high-performance liquid chromatographic method using uv detection for thedetermination of 10 drugs of abuse is described. The method is sample and sensitive. The linear rangesare 20 ̄100ng/ml with relative standard ... A high-performance liquid chromatographic method using uv detection for thedetermination of 10 drugs of abuse is described. The method is sample and sensitive. The linear rangesare 20 ̄100ng/ml with relative standard deviations of 0.7  ̄ 2.6% (n=7) and detection limits of 5 ̄ 10ng/ml. 展开更多
关键词 DETERMINATION DRUGS ABUSE CHROMATOGRAPHIC
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Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair
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作者 ma, c Zhou, TH 《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第3期239-242,共4页
Different hydrolysis and extraction procedures have been studied for the determination of drugs of abuse in hair samples. The results showed that acid and enzymatic hydrolysis gave high extraction recoveries for 6-mon... Different hydrolysis and extraction procedures have been studied for the determination of drugs of abuse in hair samples. The results showed that acid and enzymatic hydrolysis gave high extraction recoveries for 6-monoacetylmorphine, morphine, codeine and heroin. Enzymatic hydrolysis was more expensive. After alkaline hydrolysis, 6-monoacetylmorphine, a unique proof of heroin abuse, could not be detected and after methanolic extraction, the extract was dirty and the obtained chromatogram showed an interfering background. It is concluded that acid hydrolysis is the extraction method of choice. 展开更多
关键词 drugs of abuse HYDROLYSIS HAIR
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