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In silico product design of pharmaceuticals
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作者 Johan Boetker Dhara Raijada +7 位作者 Johanna Aho Milad Khorasani SФren V.SФgaard Loerke Arnfast Adam Bohr magnus edinger Jorrit J.Water Jukka Rantanen 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2016年第4期492-499,共8页
The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may scale toward infinity, their uniqueness requires a versatile ... The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may scale toward infinity, their uniqueness requires a versatile production platform and numerical simulation in order to be manufactured efficiently. A mathematical description of these systems is the only feasible approach to manage such diverse properties of different products. However,experimental verification is still essential for evaluation of processability and related concomitant phenomena, such as possible solid state changes that may occur during production and storage. 展开更多
关键词 Personalized medicine SIMULATION RHEOLOGY IMAGING Continuous manufacturing EXTRUSION
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