Fifteen pathogenic fungi were isolated from patients with external ear infection like Aspergillus niger and 100 pathogenic fungi were isolated from patients with skin infections like Trichophyton mentagrophytes which ...Fifteen pathogenic fungi were isolated from patients with external ear infection like Aspergillus niger and 100 pathogenic fungi were isolated from patients with skin infections like Trichophyton mentagrophytes which was isolated from body skin infections （also four different species of the genus Trichophyton was isolated） as well as another fungus which is Microsporum audouinii was isolated from the head scalp, and Aspergillus ustus which was isolated as normal flora from infected skin inflammation These fungi are opportunistic that can cause skin infections and inflammation of the external ear which increases the severity and the length of the disease, so the effect of different concentrations of alcoholic extract of sage leaves was tested against these fungi and it was found that the extract had an inhibition effect on growth of the fungus A. ustus by 80.7% at a concentration of 20 mg/mL, while inhibited the fungus A. niger by 77.3% at the same concentration, whereas inhibited the fungus T. mentagrophyte by 53.3% at the same concentration, and the fungus Microsporum audouinii was inhibited at the same concentration by 86.6%, also the extract showed different inhibition values against the other four species of the fungus Trichophyton. The plant sage is considered as good antifungal towards studied fungi of otitis extema and skin diseases and can be used prospectively as antifungal antibiotics against fungi causing external ear infections and skin infections.展开更多
文摘Fifteen pathogenic fungi were isolated from patients with external ear infection like Aspergillus niger and 100 pathogenic fungi were isolated from patients with skin infections like Trichophyton mentagrophytes which was isolated from body skin infections （also four different species of the genus Trichophyton was isolated） as well as another fungus which is Microsporum audouinii was isolated from the head scalp, and Aspergillus ustus which was isolated as normal flora from infected skin inflammation These fungi are opportunistic that can cause skin infections and inflammation of the external ear which increases the severity and the length of the disease, so the effect of different concentrations of alcoholic extract of sage leaves was tested against these fungi and it was found that the extract had an inhibition effect on growth of the fungus A. ustus by 80.7% at a concentration of 20 mg/mL, while inhibited the fungus A. niger by 77.3% at the same concentration, whereas inhibited the fungus T. mentagrophyte by 53.3% at the same concentration, and the fungus Microsporum audouinii was inhibited at the same concentration by 86.6%, also the extract showed different inhibition values against the other four species of the fungus Trichophyton. The plant sage is considered as good antifungal towards studied fungi of otitis extema and skin diseases and can be used prospectively as antifungal antibiotics against fungi causing external ear infections and skin infections.
