Rosacea is a common disease,but its pathogenesis is still poorly understood.For instance,there is a hypothesis in which subtypes develop in an array or another where subtypes are likely to present separately as part o...Rosacea is a common disease,but its pathogenesis is still poorly understood.For instance,there is a hypothesis in which subtypes develop in an array or another where subtypes are likely to present separately as part of a syndrome.On the other hand,with the improvement in healthcare and diagnosis techniques,more designed studies have been conducted to investigate associated factors of rosacea such as the effect of sunlight,climate and other risk factors.In this study,updates have展开更多
Objective To assess which of topical tacrolimus and topical highly potent steroids,is more effective and safer in the treatment of pediatric vitiligo.Methods The PubMed,Cochrane library,Scopus and CINAHL plus database...Objective To assess which of topical tacrolimus and topical highly potent steroids,is more effective and safer in the treatment of pediatric vitiligo.Methods The PubMed,Cochrane library,Scopus and CINAHL plus databases were retrieved.The search was confined to English language articles.The randomized controlled trial(RCT)articles were included in our study.The quality of the identified articles was examined by using the CASP Randomised Controlled Trials Checklist.Results As a result,there were only a few studies related to the comparison.However,there were only two RCTs regarding a comparison of topical tacrolimus 0.1%and clobetasol propionate 0.05%in childhood vitiligo.Conclusion When the body surface area(BSA)involved in the child is<20%,and the disease is not rapidly spreading,topical therapy is the first choice.Topical tacrolimus may be considered as an alternative therapy for childhood vitiligo,especially for acrofacial and segmental types,before considering other modalities,but still need to observe long-term side effects.展开更多
文摘Rosacea is a common disease,but its pathogenesis is still poorly understood.For instance,there is a hypothesis in which subtypes develop in an array or another where subtypes are likely to present separately as part of a syndrome.On the other hand,with the improvement in healthcare and diagnosis techniques,more designed studies have been conducted to investigate associated factors of rosacea such as the effect of sunlight,climate and other risk factors.In this study,updates have
文摘Objective To assess which of topical tacrolimus and topical highly potent steroids,is more effective and safer in the treatment of pediatric vitiligo.Methods The PubMed,Cochrane library,Scopus and CINAHL plus databases were retrieved.The search was confined to English language articles.The randomized controlled trial(RCT)articles were included in our study.The quality of the identified articles was examined by using the CASP Randomised Controlled Trials Checklist.Results As a result,there were only a few studies related to the comparison.However,there were only two RCTs regarding a comparison of topical tacrolimus 0.1%and clobetasol propionate 0.05%in childhood vitiligo.Conclusion When the body surface area(BSA)involved in the child is<20%,and the disease is not rapidly spreading,topical therapy is the first choice.Topical tacrolimus may be considered as an alternative therapy for childhood vitiligo,especially for acrofacial and segmental types,before considering other modalities,but still need to observe long-term side effects.
