Aim:Brain abscess still poses a public health challenge in spite of the advent of modern neurosurgical techniques and antibiotics.Here,we present our surgical experiences and ultimate outcome in the management of brai...Aim:Brain abscess still poses a public health challenge in spite of the advent of modern neurosurgical techniques and antibiotics.Here,we present our surgical experiences and ultimate outcome in the management of brain abscess.Methods:Totally,162 patients with proved brain abscess who underwent surgical treatment were included in this study.The prospectively recorded data of surgical management of brain abscess and the ultimate outcome(by Glasgow outcome scale)were studied retrospectively.Results:Total number of cases was 162,of which 113 were acute pyogenic abscess while 49 were chronic abscess.Among the chronic abscess,29 were chronic pyogenic abscess,14 were tubercular,3 aspergillus,and 3 abscesses were in malignant brain metastases.In acute cases,common clinical features were headache,fever,vomiting,focal deficit and seizure.In chronic abscesses,common clinical features were mild to moderate headache and progressive focal deficit.Seventy-three(45.06%)patients had adjacent localized sinus,middle ear or cranial infection.The common predisposing factors included postneurosurgery,postpenetrating injury to brain,chronic suppurative otitis media,and congenital heart disease,infective endocarditis,sinusitis and sub optimum immuno-status.Frontal lobe involved in 30.2%cases,temporal lobe is next to involved.Single time burr hole aspiration in 111(68.5%)cases,two or more times burr hole aspiration were done in 34(21%)cases.Pus culture was negative in 129(79.62%)cases.Total number of death was 22(13.58%)cases.Complete resolution of abscess with complete recovery of preoperative neuro-deficit was seen in 80.86%cases and recovery with major neuro-deficit was observed in 5.55%cases.There is a significant association between Glasgow coma scale(GCS)on admission and mortality in brain abscess.Conclusion:In most of the cases,pus culture did not yield growth of any causative organism.Mortality was not directly related to surgical intervention,but GCS on admission has a significant association with mortality.Early diagnosis,optimum follow-up and timely surgical interventions are the keys in the proper management of brain abscess.展开更多
文摘Aim:Brain abscess still poses a public health challenge in spite of the advent of modern neurosurgical techniques and antibiotics.Here,we present our surgical experiences and ultimate outcome in the management of brain abscess.Methods:Totally,162 patients with proved brain abscess who underwent surgical treatment were included in this study.The prospectively recorded data of surgical management of brain abscess and the ultimate outcome(by Glasgow outcome scale)were studied retrospectively.Results:Total number of cases was 162,of which 113 were acute pyogenic abscess while 49 were chronic abscess.Among the chronic abscess,29 were chronic pyogenic abscess,14 were tubercular,3 aspergillus,and 3 abscesses were in malignant brain metastases.In acute cases,common clinical features were headache,fever,vomiting,focal deficit and seizure.In chronic abscesses,common clinical features were mild to moderate headache and progressive focal deficit.Seventy-three(45.06%)patients had adjacent localized sinus,middle ear or cranial infection.The common predisposing factors included postneurosurgery,postpenetrating injury to brain,chronic suppurative otitis media,and congenital heart disease,infective endocarditis,sinusitis and sub optimum immuno-status.Frontal lobe involved in 30.2%cases,temporal lobe is next to involved.Single time burr hole aspiration in 111(68.5%)cases,two or more times burr hole aspiration were done in 34(21%)cases.Pus culture was negative in 129(79.62%)cases.Total number of death was 22(13.58%)cases.Complete resolution of abscess with complete recovery of preoperative neuro-deficit was seen in 80.86%cases and recovery with major neuro-deficit was observed in 5.55%cases.There is a significant association between Glasgow coma scale(GCS)on admission and mortality in brain abscess.Conclusion:In most of the cases,pus culture did not yield growth of any causative organism.Mortality was not directly related to surgical intervention,but GCS on admission has a significant association with mortality.Early diagnosis,optimum follow-up and timely surgical interventions are the keys in the proper management of brain abscess.
