Dear editor,Thrombotic thrombocytopenic purpura(TTP)is an acute non-immune acquired microangiopathic hemolytic anaemia.It is characterized by the classic pentad features of fever,thrombocytopenia,hemolytic anemia,neur...Dear editor,Thrombotic thrombocytopenic purpura(TTP)is an acute non-immune acquired microangiopathic hemolytic anaemia.It is characterized by the classic pentad features of fever,thrombocytopenia,hemolytic anemia,neurological symptoms and renal dysfunction,although all five clinical features are seen in less than 10%of patients[1].The diagnosis of TTP is frequently neglected since thrombocytopenia is a common hematological finding in patients with TTP and human immunodeficiency virus(HIV)infection.The peripheral blood film composed of schistocytes(fragmented red blood cells)plays a crucial role in diagnosing TTP associated with a chronic infection such as HIV.展开更多
文摘Dear editor,Thrombotic thrombocytopenic purpura(TTP)is an acute non-immune acquired microangiopathic hemolytic anaemia.It is characterized by the classic pentad features of fever,thrombocytopenia,hemolytic anemia,neurological symptoms and renal dysfunction,although all five clinical features are seen in less than 10%of patients[1].The diagnosis of TTP is frequently neglected since thrombocytopenia is a common hematological finding in patients with TTP and human immunodeficiency virus(HIV)infection.The peripheral blood film composed of schistocytes(fragmented red blood cells)plays a crucial role in diagnosing TTP associated with a chronic infection such as HIV.
