Background: The heart and great vessels were once thought to be relatively resistant to the damaging effect of radiation therapy. There is now clear evidence that thoracic irradiation may cause acute inflammation and ...Background: The heart and great vessels were once thought to be relatively resistant to the damaging effect of radiation therapy. There is now clear evidence that thoracic irradiation may cause acute inflammation and progressive fibrosis of different structures, including the heart valves, the myocardium and the pericardium, the coronary arteries and the conduction system. As new therapies have improved survival, many patients with cancer (mostly Hodgkin’s disease and breast cancer) are now at risk of cardiovascular (CV) complications following radiation therapy. Objectives: To raise awareness of CV complications following chest irradiation. Method: We present 5 patients that we treated during a short period of time (between June 2013 (6/2013) and February 2015 (2/2016)), who suffered CV involvement that needed therapy, following chest irradiation. Conclusions: Patients after chest irradiation should be followed periodically, in order to diagnose and treat CV complications, in time.展开更多
Cardiac Sarcoidosis (CS) is a rare and deceptive disease affecting young adults with catastrophic results including life threatening arrhythmia, congestive heart failure and even sudden death as the initial presentati...Cardiac Sarcoidosis (CS) is a rare and deceptive disease affecting young adults with catastrophic results including life threatening arrhythmia, congestive heart failure and even sudden death as the initial presentation. CS has been linked to a significant high morbidity & mortality. We present two patients: The first patient with an initial cardiac event that led us to a diagnosis of Pulmonary and Cardiac Sarcoidosis. A second patient, who was diagnosed initially with pulmonary Sarcoidosis, presented with a severe heart conduction abnormality. Both patients were successfully treated with permanent pacemakers. The dual purpose of our study is first to emphasize the importance of follow up on patients with Non-Cardiac Sarcoidosis for cardiac involvement and secondly to increase awareness of CS as part of a differential diagnosis among young adults with unexplained arrhythmia.展开更多
文摘Background: The heart and great vessels were once thought to be relatively resistant to the damaging effect of radiation therapy. There is now clear evidence that thoracic irradiation may cause acute inflammation and progressive fibrosis of different structures, including the heart valves, the myocardium and the pericardium, the coronary arteries and the conduction system. As new therapies have improved survival, many patients with cancer (mostly Hodgkin’s disease and breast cancer) are now at risk of cardiovascular (CV) complications following radiation therapy. Objectives: To raise awareness of CV complications following chest irradiation. Method: We present 5 patients that we treated during a short period of time (between June 2013 (6/2013) and February 2015 (2/2016)), who suffered CV involvement that needed therapy, following chest irradiation. Conclusions: Patients after chest irradiation should be followed periodically, in order to diagnose and treat CV complications, in time.
文摘Cardiac Sarcoidosis (CS) is a rare and deceptive disease affecting young adults with catastrophic results including life threatening arrhythmia, congestive heart failure and even sudden death as the initial presentation. CS has been linked to a significant high morbidity & mortality. We present two patients: The first patient with an initial cardiac event that led us to a diagnosis of Pulmonary and Cardiac Sarcoidosis. A second patient, who was diagnosed initially with pulmonary Sarcoidosis, presented with a severe heart conduction abnormality. Both patients were successfully treated with permanent pacemakers. The dual purpose of our study is first to emphasize the importance of follow up on patients with Non-Cardiac Sarcoidosis for cardiac involvement and secondly to increase awareness of CS as part of a differential diagnosis among young adults with unexplained arrhythmia.
