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3D打印微创导向模板在术后复发性宫颈癌近距离治疗中的临床应用 被引量:21
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作者 袁香坤 崔芒芒 +4 位作者 苗珺珺 郜蕾 胡建伟 田丹丹 张永侠 《中国肿瘤临床》 CAS CSCD 北大核心 2018年第24期1258-1262,共5页
目的:探讨3D打印微创导向模板在术后复发性宫颈癌三维插植后装治疗中的临床应用。方法:收集2017年7月至2018年4月10例就诊于河北省沧州中西医结合医院,术后复发的宫颈癌患者行个体化3D打印微创导向模板辅助下三维插植后装治疗的临床资... 目的:探讨3D打印微创导向模板在术后复发性宫颈癌三维插植后装治疗中的临床应用。方法:收集2017年7月至2018年4月10例就诊于河北省沧州中西医结合医院,术后复发的宫颈癌患者行个体化3D打印微创导向模板辅助下三维插植后装治疗的临床资料。根据患者具体情况选用不同阴道定位模板,行CT模拟定位,勾画靶区,设计主要导向针道空间分布,打印出3D微创导向模板。根据预设针道植入插植针,制定治疗计划,高危临床靶区(high risk-clinical target volume,HR-CTV)处方剂量为6 Gy/次,共4~6次。结果:10例患者共行插植治疗52次,每次插植治疗平均扫描CT次数为(1.58±0.70)次,每次插植治疗从插植针植入至插植针到达满意位置的平均消耗时间为(10.88±2.94)min,每次治疗插植针的使用针数为(5.69±1.91)根。剂量参数HR-CTV包绕90%靶区体积的剂量(D90)为(6.41±0.29)Gy,包绕膀胱、直肠、乙状结肠的2 cm3体积的剂量(D2cm3)分别为(4.75±0.37)、(3.93±0.26)、(4.33±0.24)Gy。10例患者治疗结束3个月后进行疗效评价,8例达完全缓解(complete response,CR)、2例达部分缓解(par-tial response,PR)。结论:3D打印微创导向模板应用于术后中心型复发性宫颈癌三维插植后装治疗,定位准确,可重复治疗,插植操作时间短,插植针数少,患者痛苦小,并发症少而轻,肿瘤缩小明显,具有良好的应用前景。 展开更多
关键词 术后复发性宫颈癌 3D打印微创导向模板 插植后装治疗
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Modified Blumgart anastomosis without pancreatic duct-to-jejunum mucosa anastomosis for pancreatoduodenectomy:a feasible and safe novel technique 被引量:6
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作者 Xiaoqing Wang Yang Bai +4 位作者 mangmang cui Qingxiang Zhang Wei Zhang Feng Fang Tianqiang Song 《Cancer Biology & Medicine》 SCIE CAS CSCD 2018年第1期79-87,共9页
Objective:This study proposed a modified Blumgart anastomosis(m-BA)that uses a firm ligation of the main pancreatic duct with a supporting tube to replace the pancreatic duct-to-jejunum mucosa anastomosis,with the aim... Objective:This study proposed a modified Blumgart anastomosis(m-BA)that uses a firm ligation of the main pancreatic duct with a supporting tube to replace the pancreatic duct-to-jejunum mucosa anastomosis,with the aim of simplifying the complicated steps of the conventional BA(c-BA).Thus,we observe if a difference in the risk of postoperative pancreatic fistula(POPF)exists between the two methods.Methods:The m-BA anastomosis method has been used since 2010.From October 2011 to October 2015,147 patients who underwent pancreatoduodenectomy(PD)using BA in Tianjin Medical University Cancer Institute and Hospital were enrolled in this study.According to the type of pancreatojejunostomy(PJ),50 patients underwent m-BA and 97 received c-BA.The two patient cohorts were compared prospectively to some extent but not randomized,and the evaluated variables were operation time,the incidence rate of POPF,and other perioperative complications.Results:The operation time showed no significant difference(P>0.05)between the two groups,but the time of duct-to-mucosa anastomosis in the m-BA group was much shorter than that in the c-BA group(P<0.001).The incidence rate of clinically relevant POPF was 12.0%(6/50)in the modified group and 10.3%(10/97)in the conventional group(P>0.05),which means that the modified anastomosis method did not cause additional pancreatic leakage.The mean length of postoperative hospital stay of the m-BA group was 23 days,and that of the c-BA group was 22 days(P>0.05).Conclusions:Compared with the conventional BA,we suggest that the modified BA is a feasible,safe,and effective operation method for P J of PD with no sacrifice of surgical quality.In the multivariate analysis,we also found that body mass 展开更多
关键词 胰腺 修改 技术 安全 结扎 试管 手术
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