Dear Editor,N 6-methyladenosine(m^(6)A)is a critical mRNA modi-fication catalyzed by the enzyme methyltransferase-like 3(METTL3),with implications in RNA metabolism.METTL3 upregulation is associated with cancer progre...Dear Editor,N 6-methyladenosine(m^(6)A)is a critical mRNA modi-fication catalyzed by the enzyme methyltransferase-like 3(METTL3),with implications in RNA metabolism.METTL3 upregulation is associated with cancer progres-sion,metastasis,and drug resistance,making it a poten-tial therapeutic target[1].展开更多
基金This work was supported by NextGenerationEU-PNRR M4C2-Investment 1.4-CN00000041 to A.F.,F.F.,and L.D.G.,“Progetti Ateneo Sapienza”RP1201729D714976 to A.F.WorkinthelaboratoryofC.S.wassupportedbyBreast Cancer now(project 2018NovPCC1283)AIRC(project IG23416).
文摘Dear Editor,N 6-methyladenosine(m^(6)A)is a critical mRNA modi-fication catalyzed by the enzyme methyltransferase-like 3(METTL3),with implications in RNA metabolism.METTL3 upregulation is associated with cancer progres-sion,metastasis,and drug resistance,making it a poten-tial therapeutic target[1].
