Cerebellar degeneration-related antigen 1(CDR1)was described to be expressed in the nervous system and in different types of cancer tissues.In the present study,we demonstrate that CDR1 is in addition ubiquitously exp...Cerebellar degeneration-related antigen 1(CDR1)was described to be expressed in the nervous system and in different types of cancer tissues.In the present study,we demonstrate that CDR1 is in addition ubiquitously expressed in human epidermis,dermis and isolated skin cells.Both CDR1 mRNA and protein were detected in human skin-derived mast cells,melanocytes,fibroblasts and keratinocytes,suggesting that CDR1 does not have a neuron-specific function.展开更多
基金This work was supported by the Austrian Science Fund(FWF):V 548-B30 and by a research grant from CE.R.I.E.S,Neuilly,France.
文摘Cerebellar degeneration-related antigen 1(CDR1)was described to be expressed in the nervous system and in different types of cancer tissues.In the present study,we demonstrate that CDR1 is in addition ubiquitously expressed in human epidermis,dermis and isolated skin cells.Both CDR1 mRNA and protein were detected in human skin-derived mast cells,melanocytes,fibroblasts and keratinocytes,suggesting that CDR1 does not have a neuron-specific function.
