期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Tailoring Properties of Biocompatible PEG-DMA Hydrogels with UV Light
1
作者 Sania Backstrom Juana Benavente +4 位作者 Rolf W.Berg Karin Stibius marianne s.larsen Henrik Bohr Claus Hélix-Nielsen 《Materials Sciences and Applications》 2012年第6期425-431,共7页
Hydrogels are highly water-absorbent hydrophilic polymer networks, which show potential in many biocompatible applications. In previous work, we demonstrated the feasibility of using poly(ethylene glycol) dimethacryla... Hydrogels are highly water-absorbent hydrophilic polymer networks, which show potential in many biocompatible applications. In previous work, we demonstrated the feasibility of using poly(ethylene glycol) dimethacrylate (PEG-DMA) gels polymerized with a photoinitiator for encapsulation and stabilization of painted biomimetic membrane arrays for novel separation technologies or biosensor applications. These gels were formed from PEG-DMA monomers suspended in phosphate buffered saline (PBS) solution and gelated by radical polymerization in the presence of the photoinitiator Darocur 1173. In this work, we show that the properties of a PEG-DMA hydrogel formed by photoinitiated polymerizetion can be tailored by varying the photocrosslinking time. Fourier Transform Infrared Spectroscopy (FTIR) and Raman Spectroscopy (RS) showed that the optimal crosslinking time for the gel was 6 - 10 minutes and that the water content of the gels could be tuned in the range of 50 - 90 wt%. The resistivity was between 0.8 - 3.5 Ωm, which is comparable to that of PBS. The low resistivity of the gel makes it compatible for encapsulating membranes for (ion channel based) biosensor applications. With FTIR and RS we identified spectral features of the hydrogel, which may serve as a diagnostic tool to monitor changes in the gels due to variation in parameters such as time, pH, temperature, aging or exposure to chemicals or biological material. 展开更多
关键词 Hydrogel Swelling UV-Induced Polymerization FTIR Raman Spectroscopy Impedance Spectroscopy
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部