Metallic biomedical implants based on magnesium,zinc and iron alloys have emerged as bioresorbable alternatives to permanent orthopaedic implants over the last two decades.The corrosion rate of biodegradable metals pl...Metallic biomedical implants based on magnesium,zinc and iron alloys have emerged as bioresorbable alternatives to permanent orthopaedic implants over the last two decades.The corrosion rate of biodegradable metals plays a critical role in controlling the compatibility and functionality of the device in vivo.The broader adoption of biodegradable metals in orthopaedic applications depends on developing in vitro methods that accurately predict the biodegradation behaviour in vivo.However,the physiological environment is a highly complex corrosion environment to replicate in the laboratory,making the in vitro-to-in vivo translation of results very challenging.Accordingly,the results from in vitro corrosion tests fail to provide a complete schema of the biodegradation behaviour of the metal in vivo.In silico approach based on computer simulations aim to bridge the observed differences between experiments performed in vitro and vivo.A critical review of the state-of-the-art of computational modelling techniques for predicting the corrosion behaviour of magnesium alloy as a biodegradable metal is presented.展开更多
Following on from the 1st Editorial Board Meeting of Bioactive Materials(held April 2017,Minneapolis USA),the 2nd Editorial Board Meeting was held on the 28th August 2017 during the 9th Symposium on Biodegradable Meta...Following on from the 1st Editorial Board Meeting of Bioactive Materials(held April 2017,Minneapolis USA),the 2nd Editorial Board Meeting was held on the 28th August 2017 during the 9th Symposium on Biodegradable Metals for Biomedical Applications(http://biodegradablemetals.org).(see Figs.1 and 2)The Symposiumwas held in Bertinoro Italy(Emilie-Romagne region),80 km southeast of Bologna.Every year the Symposium attracts^150 participants working in the field of biodegradable metallic biomaterials,mainly based on Mg,Fe and Zn,with^50 oral presentations and 90 posters delivered at the 9th Symposium by participants from 22 countries.Sessions were organised into a range of topics including metallurgy(alloying and processing,coatings,material properties,and corrosion),research concerned with testing in vitro and in vivo,and other important aspects of biological characterisation.展开更多
基金supported by the Health Research Council of New Zealand.
文摘Metallic biomedical implants based on magnesium,zinc and iron alloys have emerged as bioresorbable alternatives to permanent orthopaedic implants over the last two decades.The corrosion rate of biodegradable metals plays a critical role in controlling the compatibility and functionality of the device in vivo.The broader adoption of biodegradable metals in orthopaedic applications depends on developing in vitro methods that accurately predict the biodegradation behaviour in vivo.However,the physiological environment is a highly complex corrosion environment to replicate in the laboratory,making the in vitro-to-in vivo translation of results very challenging.Accordingly,the results from in vitro corrosion tests fail to provide a complete schema of the biodegradation behaviour of the metal in vivo.In silico approach based on computer simulations aim to bridge the observed differences between experiments performed in vitro and vivo.A critical review of the state-of-the-art of computational modelling techniques for predicting the corrosion behaviour of magnesium alloy as a biodegradable metal is presented.
文摘Following on from the 1st Editorial Board Meeting of Bioactive Materials(held April 2017,Minneapolis USA),the 2nd Editorial Board Meeting was held on the 28th August 2017 during the 9th Symposium on Biodegradable Metals for Biomedical Applications(http://biodegradablemetals.org).(see Figs.1 and 2)The Symposiumwas held in Bertinoro Italy(Emilie-Romagne region),80 km southeast of Bologna.Every year the Symposium attracts^150 participants working in the field of biodegradable metallic biomaterials,mainly based on Mg,Fe and Zn,with^50 oral presentations and 90 posters delivered at the 9th Symposium by participants from 22 countries.Sessions were organised into a range of topics including metallurgy(alloying and processing,coatings,material properties,and corrosion),research concerned with testing in vitro and in vivo,and other important aspects of biological characterisation.