Background: Spitz nevus is uncommon, benign melanocytic neoplasm that may show some clinical, dermoscopical and histological features of melanoma. It occurs often in childhood, but may appear also in early adulthood. ...Background: Spitz nevus is uncommon, benign melanocytic neoplasm that may show some clinical, dermoscopical and histological features of melanoma. It occurs often in childhood, but may appear also in early adulthood. Rare congenital cases have been reported in literature. It is frequently located on the face and the lower extremities, but in some cases may appears on the trunk. Methods: We report a case of a 9-years-old girl presented to our Dermatology Unit because of the presence of a pigmented lesion on her right leg, 4 mm in diameter, which was clinically and dermoscopically diagnosed as Spitz nevus. We described the clinical and dermoscopic features that we observed every six months, over 11 years follow-up period. Objective: Our observation show that the globular, the starburst, the homogeneous patterns and diffuse brown colour with diffuse hypopigmented areas may be the different expression that correspond to possible evolutionary phases of pigmented Spitz nevus.展开更多
Introduction:Eruptive pseudoangiomatosis(EP)is a rare type of cutaneous exanthema characterized by red angioma-like papules.An association of EP with viral infection has been reported.We herein describe 4 pediatric pa...Introduction:Eruptive pseudoangiomatosis(EP)is a rare type of cutaneous exanthema characterized by red angioma-like papules.An association of EP with viral infection has been reported.We herein describe 4 pediatric patients who showed a new variant of EP-associated rash with atypical clinical features and positivity for parvovirus B19 infection.Case presentation:Pediatric patients showed a new variant of EP-associated rash with atypical clinical features by dermoscopy and reflectance confocal microscopy.The papules were localized to the face(cheeks,forehead,and eyelids).Dermoscopy showed multiple red dots suggesting dilated capillaries surrounded by reddish structureless areas;and in vivo reflectance confocal microscopy(RCM)showed perivascular inflammation around the dermal papillae.However,characteristic perilesional halo was absent.In all patients,serology revealed evidence of active infection by parvovirus B19.Discussion:Few cases of a facial pseudoangiomatous rash that is related to parvovirus B19 infection and lacks the typical anemic halo have been reported in the literature.Conclusion:These cases provide new information on the clinical spectrum of EP and its association with parvovirus.展开更多
文摘Background: Spitz nevus is uncommon, benign melanocytic neoplasm that may show some clinical, dermoscopical and histological features of melanoma. It occurs often in childhood, but may appear also in early adulthood. Rare congenital cases have been reported in literature. It is frequently located on the face and the lower extremities, but in some cases may appears on the trunk. Methods: We report a case of a 9-years-old girl presented to our Dermatology Unit because of the presence of a pigmented lesion on her right leg, 4 mm in diameter, which was clinically and dermoscopically diagnosed as Spitz nevus. We described the clinical and dermoscopic features that we observed every six months, over 11 years follow-up period. Objective: Our observation show that the globular, the starburst, the homogeneous patterns and diffuse brown colour with diffuse hypopigmented areas may be the different expression that correspond to possible evolutionary phases of pigmented Spitz nevus.
文摘Introduction:Eruptive pseudoangiomatosis(EP)is a rare type of cutaneous exanthema characterized by red angioma-like papules.An association of EP with viral infection has been reported.We herein describe 4 pediatric patients who showed a new variant of EP-associated rash with atypical clinical features and positivity for parvovirus B19 infection.Case presentation:Pediatric patients showed a new variant of EP-associated rash with atypical clinical features by dermoscopy and reflectance confocal microscopy.The papules were localized to the face(cheeks,forehead,and eyelids).Dermoscopy showed multiple red dots suggesting dilated capillaries surrounded by reddish structureless areas;and in vivo reflectance confocal microscopy(RCM)showed perivascular inflammation around the dermal papillae.However,characteristic perilesional halo was absent.In all patients,serology revealed evidence of active infection by parvovirus B19.Discussion:Few cases of a facial pseudoangiomatous rash that is related to parvovirus B19 infection and lacks the typical anemic halo have been reported in the literature.Conclusion:These cases provide new information on the clinical spectrum of EP and its association with parvovirus.
