AIM To develop a survey to help define the main problems in radiological clinical trials. METHODS Since 2006, we have managed seven different radiological clinical trials recruiting patients in academic and non-academ...AIM To develop a survey to help define the main problems in radiological clinical trials. METHODS Since 2006, we have managed seven different radiological clinical trials recruiting patients in academic and non-academic centres. We developed a preliminary questionnaire using a four-round Delphi approach to identify problems occurring in radiological clinical trials run at our centre. We investigated the recruitment experience, involvement of all multi-disciplinary team members and main obstacles to completing the projects. A final round of Delphi processes elucidated solutions to the identified problems.RESULTS Among 19/20(95%) respondents, 10(53%) were young physicians(under 35 years old), and the respondents included non-faculty members, fellows, residents, and undergraduate students. Ninety-four percent(18/19) of respondents showed interest in conducting clinical trials. On a scale of 1 to 10, the problems with higher/worse scores(8-9) were related to technical or communication problems. The most frequent problems across all studies were technical problems related to clinical trial equipment, insufficient willingness to participate, obstacles to understanding the design of electronic-case report form and extra work.CONCLUSION The developed questionnaire identified the main recurring problems in radiological clinical trials as perceived by endusers and helped define possible solutions that are mostly related to having dedicated clinical trial research staff.展开更多
The problem of Caesium-137 (137 Cs) contamination of the imported wood pellet used for burning has been reported in Italy since June 2009. Since then, sampling and analysis were performed at the crossing border points...The problem of Caesium-137 (137 Cs) contamination of the imported wood pellet used for burning has been reported in Italy since June 2009. Since then, sampling and analysis were performed at the crossing border points of the provinces of Trieste and Gorizia, on request of the Health and Customs Border Bureau. This paper presents the results of the analysis performed on 65 samples from August 2010 to March 2012, which covered a total of products over 1500 tons of various origins, imported from Eastern Europe and the Balkans. Most of the samples showed very low 137 Cs activity concentrations;only a few hot spots showed 137 Cs activity concentrations higher than 100 Bq·kg-1. The results of dose evaluations for wood pellet stoves users under the hypotheses assumed in this study were largely below the threshold of radiological relevance.展开更多
文摘AIM To develop a survey to help define the main problems in radiological clinical trials. METHODS Since 2006, we have managed seven different radiological clinical trials recruiting patients in academic and non-academic centres. We developed a preliminary questionnaire using a four-round Delphi approach to identify problems occurring in radiological clinical trials run at our centre. We investigated the recruitment experience, involvement of all multi-disciplinary team members and main obstacles to completing the projects. A final round of Delphi processes elucidated solutions to the identified problems.RESULTS Among 19/20(95%) respondents, 10(53%) were young physicians(under 35 years old), and the respondents included non-faculty members, fellows, residents, and undergraduate students. Ninety-four percent(18/19) of respondents showed interest in conducting clinical trials. On a scale of 1 to 10, the problems with higher/worse scores(8-9) were related to technical or communication problems. The most frequent problems across all studies were technical problems related to clinical trial equipment, insufficient willingness to participate, obstacles to understanding the design of electronic-case report form and extra work.CONCLUSION The developed questionnaire identified the main recurring problems in radiological clinical trials as perceived by endusers and helped define possible solutions that are mostly related to having dedicated clinical trial research staff.
文摘The problem of Caesium-137 (137 Cs) contamination of the imported wood pellet used for burning has been reported in Italy since June 2009. Since then, sampling and analysis were performed at the crossing border points of the provinces of Trieste and Gorizia, on request of the Health and Customs Border Bureau. This paper presents the results of the analysis performed on 65 samples from August 2010 to March 2012, which covered a total of products over 1500 tons of various origins, imported from Eastern Europe and the Balkans. Most of the samples showed very low 137 Cs activity concentrations;only a few hot spots showed 137 Cs activity concentrations higher than 100 Bq·kg-1. The results of dose evaluations for wood pellet stoves users under the hypotheses assumed in this study were largely below the threshold of radiological relevance.