A blue light-promoted reaction between aryldiazoacetates and different nucleophiles has been developed in the presence of THF(and other cyclic ethers)as the solvent,allowing the incorporation of these three elements i...A blue light-promoted reaction between aryldiazoacetates and different nucleophiles has been developed in the presence of THF(and other cyclic ethers)as the solvent,allowing the incorporation of these three elements into a single product.Formally,this transformation represents an O–H insertion strategy of more complex alcohols into aryldiazoesters,without the need of pre-assembling them.The method is mild and efficient and proceeds in the absence of metals,generally at room temperature.展开更多
基金Financial support is greatly appreciated from CNPq for a PhD fellowship to M.L.S.(142474/2018-5)FAPESP for a post-doc-toral fellowship to R.D.C.G.(2020/00144-6)+3 种基金a Young Researcher Grant to R.A.C(2018/03910-1)a PhD fellowship to J.P.M.S.(2020/06536-3)a Regular Research Grant to I.D.J.(2019/01235-8)The authors also thank FAEPEX for a fellowship to R.A.C.(2466/20).
文摘A blue light-promoted reaction between aryldiazoacetates and different nucleophiles has been developed in the presence of THF(and other cyclic ethers)as the solvent,allowing the incorporation of these three elements into a single product.Formally,this transformation represents an O–H insertion strategy of more complex alcohols into aryldiazoesters,without the need of pre-assembling them.The method is mild and efficient and proceeds in the absence of metals,generally at room temperature.
