Aminoethyl methacrylate(AEMA) was grafted onto the polypropylene microporous membrane by photo-induced polymerization to immobilize dextran. XPS spectra confirmed the chemical change of the membrane surface after the ...Aminoethyl methacrylate(AEMA) was grafted onto the polypropylene microporous membrane by photo-induced polymerization to immobilize dextran. XPS spectra confirmed the chemical change of the membrane surface after the graft polymerization of AEMA and the immobilization of dextran. The water contact angle measurement indicated that the hydrophilicity of the membrane surface can be increased reparably by the dextran immobilization.展开更多
Two kinds of polypeptides were tethered onto the surface of polypropylene microporous membrane (PPMM) through a ring opening polymerization of L-glutamate N-carboxyanhydride initiated by amino groups which were introd...Two kinds of polypeptides were tethered onto the surface of polypropylene microporous membrane (PPMM) through a ring opening polymerization of L-glutamate N-carboxyanhydride initiated by amino groups which were introduced by ammonia plasma andγ-aminopropyl triethanoxysilane treatments. X-ray photoelectron spectroscopy (XPS), attenuated total reflectance Fourier transform infrared spectroscopy (FT-IR/ATR), scanning electron microscopy (SEM), together with water contact angle measurements were used to characterize the modified membranes. XPS analyses and FT-IR/ATR spectra demonstrated that polypeptides are actually grafted onto the membrane surface. The wettability of the membrane surface increases at first and then decreases with the increase in grafting degrees of polypeptide. Platelet adhesion and murine macrophage attachment experiments reveal an enhanced hemocompatibility for the polypeptide modified PPMMs. All these results give evidence that polypeptide grafting can simultaneously improve the hemocompatibility as well as reserve the hydrophobicity for the membrane, which will provide a potential approach to improve the performance of polypropylene hollow fiber microporous membrane used in artificial oxygenator.展开更多
文摘Aminoethyl methacrylate(AEMA) was grafted onto the polypropylene microporous membrane by photo-induced polymerization to immobilize dextran. XPS spectra confirmed the chemical change of the membrane surface after the graft polymerization of AEMA and the immobilization of dextran. The water contact angle measurement indicated that the hydrophilicity of the membrane surface can be increased reparably by the dextran immobilization.
基金This project was supported by the National Natural Science Foundation of China (No. 20074033)the National Basic Research Program of China (No. 2003CB15705).
文摘Two kinds of polypeptides were tethered onto the surface of polypropylene microporous membrane (PPMM) through a ring opening polymerization of L-glutamate N-carboxyanhydride initiated by amino groups which were introduced by ammonia plasma andγ-aminopropyl triethanoxysilane treatments. X-ray photoelectron spectroscopy (XPS), attenuated total reflectance Fourier transform infrared spectroscopy (FT-IR/ATR), scanning electron microscopy (SEM), together with water contact angle measurements were used to characterize the modified membranes. XPS analyses and FT-IR/ATR spectra demonstrated that polypeptides are actually grafted onto the membrane surface. The wettability of the membrane surface increases at first and then decreases with the increase in grafting degrees of polypeptide. Platelet adhesion and murine macrophage attachment experiments reveal an enhanced hemocompatibility for the polypeptide modified PPMMs. All these results give evidence that polypeptide grafting can simultaneously improve the hemocompatibility as well as reserve the hydrophobicity for the membrane, which will provide a potential approach to improve the performance of polypropylene hollow fiber microporous membrane used in artificial oxygenator.
