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Loss of ID3 in pancreatic cancer cells increases DNA damage without impairingMDC1 recruitment to the nuclear foci 被引量:2
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作者 Jian Xu mayrel palestino dominguez Christine Alewine 《Cancer Communications》 SCIE 2022年第3期269-272,共4页
Dear Editor,Pancreatic cancer is one of the most aggressive human cancers and is predicted to become the second leading cause of cancer-related death by the year 2030[1,2].In the United States,approximately 60,000 new... Dear Editor,Pancreatic cancer is one of the most aggressive human cancers and is predicted to become the second leading cause of cancer-related death by the year 2030[1,2].In the United States,approximately 60,000 newly diagnosed cases and 48,000 deaths were estimated to occur in 2021[3].Because early screening is very difficult and most patients are diagnosed with advanced disease,curing pancreatic cancer patients still faces huge challenges.Accordingly,a comprehensive understanding of the pathogenesis of pan-creatic cancer is required to promote the development of efficient treatment modalities. 展开更多
关键词 damage DEATH ID3
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