Aim: To determine the association between Viagra (sildenafil)-and Cialis (tadalafil) and non-arteritic anterior ischaemic optic neuropathy (NAION).Methods: A retrospective matched case control study was conducted. 38 ...Aim: To determine the association between Viagra (sildenafil)-and Cialis (tadalafil) and non-arteritic anterior ischaemic optic neuropathy (NAION).Methods: A retrospective matched case control study was conducted. 38 cases of NAION in males were identified from an academic ophthalmology practice in Birmingham, Alabama, and matched (on age) to 38 controls without a history of NAION. Self reported information regarding past and current use of Viagra and/or Cialis was obtained via a telephone questionnaire from interviewers who were not blind to case status. Results: Overall, males with NAION were no more likely to report a history of Viagra or Cialis use compared to similarly aged controls (odd ratio (OR) 1.75, 95%confidence interval (CI) 0.48 to 6.30 and OR 1.82, 95%CI 0.21 to 15.39). However, for those with a history of myocardial infarction, a statistically significant association was observed (OR 10.7, 95%CI 1.3 to 95.8). A similar association was observed for those with a history of hypertension though it lacked statistical significance (OR 6.9, 95%CI 0.8 to 63.6). Conclusions: For men with a history of myocardial infarction or hypertension the use of Viagra or Cialis may increase the risk of NAION. Physicians prescribing these medications to patients with these conditions should warn them about the potential risk ofNAION.展开更多
Objective: To provide a comprehensive estimate of the rate of eye injury in the United States. Methods: Data from the National Ambulatory Medical Care Survey, the National Hospital Ambulatory Medical Care Survey, and ...Objective: To provide a comprehensive estimate of the rate of eye injury in the United States. Methods: Data from the National Ambulatory Medical Care Survey, the National Hospital Ambulatory Medical Care Survey, and the National Hospital Discharge Survey for 2001 were combined and used to provide estimates of eye injuries treated in emergency departments, inpatient and outpatient facilities, and private physician’s offices, as well as their causes and characteristics. Results: In the United States in 2001, an estimated 1 990 872 (6.98 per 1000 population) individuals experienced an eye injury requiring treatment in an emergency department, inpatient or outpatient facility, or private physician’s office. Most eye injuries are treated in emergency departments (50.7% ), followed by private physicians’offices (38.7% ), and outpatient (8.1% ) and inpatient (2.5% ) facilities. Eye injury rates were highest among individuals in their 20s, males, and whites. Injury rates were highest for superficial injuries, foreign bodies, contusions, and open wounds. Conclusions: This study provides a comprehensive estimate of the rate of eye injury in the United States. Private physicians represent an important source of care for eye injury in the United States.展开更多
文摘Aim: To determine the association between Viagra (sildenafil)-and Cialis (tadalafil) and non-arteritic anterior ischaemic optic neuropathy (NAION).Methods: A retrospective matched case control study was conducted. 38 cases of NAION in males were identified from an academic ophthalmology practice in Birmingham, Alabama, and matched (on age) to 38 controls without a history of NAION. Self reported information regarding past and current use of Viagra and/or Cialis was obtained via a telephone questionnaire from interviewers who were not blind to case status. Results: Overall, males with NAION were no more likely to report a history of Viagra or Cialis use compared to similarly aged controls (odd ratio (OR) 1.75, 95%confidence interval (CI) 0.48 to 6.30 and OR 1.82, 95%CI 0.21 to 15.39). However, for those with a history of myocardial infarction, a statistically significant association was observed (OR 10.7, 95%CI 1.3 to 95.8). A similar association was observed for those with a history of hypertension though it lacked statistical significance (OR 6.9, 95%CI 0.8 to 63.6). Conclusions: For men with a history of myocardial infarction or hypertension the use of Viagra or Cialis may increase the risk of NAION. Physicians prescribing these medications to patients with these conditions should warn them about the potential risk ofNAION.
文摘Objective: To provide a comprehensive estimate of the rate of eye injury in the United States. Methods: Data from the National Ambulatory Medical Care Survey, the National Hospital Ambulatory Medical Care Survey, and the National Hospital Discharge Survey for 2001 were combined and used to provide estimates of eye injuries treated in emergency departments, inpatient and outpatient facilities, and private physician’s offices, as well as their causes and characteristics. Results: In the United States in 2001, an estimated 1 990 872 (6.98 per 1000 population) individuals experienced an eye injury requiring treatment in an emergency department, inpatient or outpatient facility, or private physician’s office. Most eye injuries are treated in emergency departments (50.7% ), followed by private physicians’offices (38.7% ), and outpatient (8.1% ) and inpatient (2.5% ) facilities. Eye injury rates were highest among individuals in their 20s, males, and whites. Injury rates were highest for superficial injuries, foreign bodies, contusions, and open wounds. Conclusions: This study provides a comprehensive estimate of the rate of eye injury in the United States. Private physicians represent an important source of care for eye injury in the United States.
