面向新型电力系统的多元协调规划模型构建方法

为获取相对可控的电力输出额,并确保电力系统的安全稳定高效运行,基于多元接入的发展趋势与电碳耦合的发展路径,结合系统需求预测、电力电量平衡和可再生能源配额等,提出一种多元协调规划模型的构建方法。模拟实验证明,建立的模型可以测算电碳成本,规划结果可以用于缓解电力资源和负载需求之间的不一致性问题,为后续增加清洁能源的安装比例、减少碳排、优化电力结构提供理论参考。

以某党校为对象的智慧校园业务系统建设研究

加快智慧校园建设是抢抓信息化发展机遇、实现教育现代化的重要举措。业务系统是智慧校园的重要组成部分。文章以某党校为研究对象,首先分析了现有业务系统存在的问题及原因;其次提出了智慧校园业务系统的建设目标是实现数据互通和业务联通;然后探讨了智慧校园业务系统的建设内容,具体包括1个信息化平台、1个信息门户、3大应用中心;最后,从强化顶层设计、搭建数据平台、推动虚实融合、加强安全防护四个方面提出了智慧校园业务系统建设的行动建议。

Erythropoietin-induced hepatocyte receptor A2 regulates effect of pyroptosis on gastrointestinal colorectal cancer occurrence and metastasis resistance

Erythropoietin-induced hepatocyte receptor A2(EphA2)is a receptor tyrosine kinase that plays a key role in the development and progression of a variety of tumors.This article reviews the expression of EphA2 in gastrointestinal(GI)colorectal cancer(CRC)and its regulation of pyroptosis.Pyroptosis is a form of programmed cell death that plays an important role in tumor suppression.Studies have shown that EphA2 regulates pyrodeath through various signaling pathways,affecting the occurrence,development and metastasis of GI CRC.The overexpression of EphA2 is closely related to the aggressiveness and metastasis of GI CRC,and the inhibition of EphA2 can induce pyrodeath and improve the sensitivity of cancer cells to treatment.In addition,EphA2 regulates intercellular communication and the microenvironment through interactions with other cytokines and receptors,further influencing cancer progression.The role of EphA2 in GI CRC and its underlying mechanisms provide us with new perspectives and potential therapeutic targets,which have important implications for future cancer treatment.

Exploring the molecular mechanism of Solanum nigrum L in breast cancer treatment through network pharmacology and molecular docking validation

In 2020,breast cancer emerged as the leading type of cancer worldwide,surpassing lung cancer in the number of new cases.The high cost and frequent failure of current treatments due to drug resistance and other challenges underscore the urgent need for novel,affordable,efficient,and less toxic breast cancer therapies with fewer side effects.This study aims to investigate the molecular mechanisms by which Solanum Nigrum L.counters breast cancer,employing network pharmacology and molecular docking methods.Methods:The study identified the primary active compounds of Solanum Nigrum L.using databases such as TCMSP,TCM-ID,NPASS,and BATMAN.Prediction of the compounds'targets was facilitated by the SwissADME website,while main breast cancer targets were sourced from the GeneCards,OMIM,and TTD databases.The identified drug-disease intersection targets were analyzed using the STRING platform to construct a protein interaction network,which was then visualized and refined to select hub targets using Cytoscape 3.9.0 software.The Metascape database's MOCDE functional plugin was employed for identifying potential functional modules within the protein interaction network.Further,the DAVID database was utilized for GO and KEGG enrichment analyses of the intersection targets.Molecular docking of key active compounds with core targets was performed using AutoDock Tools 1.5.7 software.Lastly,the GEPIA2.0 database was used for predicting overall survival curves of hub targets and conducting a pan-cancer analysis.Results:Eleven active compounds of Solanum Nigrum L.,including Diosgenin,Tigogenin,and Quercetin,were identified from traditional Chinese medicine databases.We discovered 113 targets common to both Solanum Nigrum L.and breast cancer.Solanum Nigrum L.exhibits anti-breast cancer properties through interactions with 14 key targets,including SRC,PIK3R1,HSP90AA1,PIK3CA,AKT1,VEGFA,and ESR1.These interactions influence several critical signaling pathways,notably the cancer signaling pathway,PI3K-Akt signaling pathway,Ras signaling pathway,and EGFR signaling pathway.Survival analysis indicated that the aberrant expression of these 14 key targets significantly affects patient survival times.Furthermore,pan-cancer analysis highlighted marked differences in the expression patterns of these targets between breast cancer patients and control groups.Conclusion:Solanum Nigrum L.mediates its therapeutic impact on breast cancer through a comprehensive approach,targeting multiple components,targets,and pathways.

基于熵权-灰色层次分析的MSaaS可信度评估

建模仿真即服务(Modelling Simulation as a service, MSaaS)是将云计算、面向服务的架构等技术引入建模与仿真领域的新思想,其建立的仿真系统的可信度是完成高性能仿真的基础问题与重要指标。分析了建模仿真即服务的分层体系架构,根据其架构各层之间的功能不同,运行环境异构等特点建立了可信度评估指标体系,提出了一种定量计算和定性分析相结合的评估方法——熵权-灰色层次分析法,最后给出了基于MSaaS的战场环境仿真可信度评估实例,结果表明上述方法有效。

ReaxFF力场方法及其在含能材料中应用的研究进展

从ReaxFF分子动力学在含能材料领域的研究出发,聚焦于研究ReaxFF力场的构成和发展、力场优化方法和应用等方面。在力场开发方法方面,对局域优化方法和全局优化方法进行了重点介绍,其中多目标进化策略、增强的粒子群优化算法和基于神经网络等开发策略均有所涵盖。ReaxFF力场在含能材料模拟中的应用主要集中于探索微观结构反应性、动态演化、初始化学分解路径以及中间和稳定产物分布。根据外部条件不同而分为加热和加压、冲击加载、激光和电场等应用场景。研究主体涉及单质/共混/共晶炸药、含有缺陷炸药以及金属复合炸药。最后,针对ReaxFF的准确性和迁移性进行了展望,认为在人工智能框架下的ReaxFF反应力场训练可以大幅提高其在复杂反应中的准确性。在连续体仿真模型中,若将其局域反应度等关键指标的唯象规律替换为基于ReaxFF的反应规律,将是实现一个包含力学和化学动力学响应耦合的多尺度全流程仿真计算的重要途径。附参考文献134篇。

Recent Progress in Atmospheric Chemistry Research in China: Establishing a Theoretical Framework for the “Air Pollution Complex”

Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in 1997.For papers published in 2021 on air pollution(only papers included in the Web of Science Core Collection database were considered),more than 24000 papers were authored or co-authored by scientists working in China.In this paper,we review a limited number of representative and significant studies on atmospheric chemistry in China in the last few years,including studies on(1)sources and emission inventories,(2)atmospheric chemical processes,(3)interactions of air pollution with meteorology,weather and climate,(4)interactions between the biosphere and atmosphere,and(5)data assimilation.The intention was not to provide a complete review of all progress made in the last few years,but rather to serve as a starting point for learning more about atmospheric chemistry research in China.The advances reviewed in this paper have enabled a theoretical framework for the air pollution complex to be established,provided robust scientific support to highly successful air pollution control policies in China,and created great opportunities in education,training,and career development for many graduate students and young scientists.This paper further highlights that developing and low-income countries that are heavily affected by air pollution can benefit from these research advances,whilst at the same time acknowledging that many challenges and opportunities still remain in atmospheric chemistry research in China,to hopefully be addressed over the next few decades.

基于战场元宇宙的动态三维场景感知

信息化作战对战场的态势感知提出了更高的要求,利用无人智能体进行战场侦察并感知目标信息尤为重要。基于战场元宇宙目标数据与作战环境,面向复杂动态环境定位与目标识别的需求,提出并构建了动态三维场景感知系统,使用视觉和IMU融合传感器仿真数据作为输入,通过实例分割和稠密光流估计网络提取战场目标信息并作为场景先验,在SLAM和优化过程中同步完成无人智能体在战场中的位姿估计与对战场目标的跟踪。实验结果表明:系统能够在战场动态复杂环境下给出场景稀疏重建与无人智能体准确的定位,持续输出每一个战场目标类型、位置、速度等信息,表现出良好的精度与鲁棒性,为战场态势融合等其他模块提供技术支撑。

直接化学气相沉积法制备二维钴铁氧体用于高效析氧反应

二维(2D)过渡金属氧化物(TMO)的地球丰度高,并且具有独特的物理化学性质和较好的催化性能,是新能源工业领域中非常有应用前景的电催化剂.然而,由于合成高质量和可控厚度的2D TMO具有一定的难度,目前有关2D TMO的微观电化学研究的报道较少.本文采用化学气相沉积法直接合成了2D钴铁氧体(CoFeO),所制得的2D CoFeO呈现结晶性良好的超薄尖晶石结构,其最薄厚度可达到6.8 nm.采用超微电极测试平台考察了碱性条件下2DCoFeO催化析氧反应(OER)的性能.结果表明,2D CoFeO(111)面在10 m Acm^(-2)的电流密度下表现出330 m V的低过电位,在570 m V的过电位下表现出142 m Acm^(-2)的高电流密度.密度泛函理论计算发现2DCoFeO表面上的双金属位点降低了反应能垒.此外,2DCoFeO的超薄厚度使体电阻率降低,同时增加了活性位点的利用率,进而提高了对OER的催化活性,这与在超微电极平台上测得的2D CoFeO厚度-OER活性依赖关系的结果一致.本研究还合成了大面积的2D CoFeO薄膜,其标准三电极体系研究表明2D CoFeO样品仍然表现出较高的催化OER活性和较好的寿命,说明所制备的2D CoFeO具有较好的实际应用潜力.综上,本文采用气相化学沉积法直接合成了超薄2DCoFeO纳米片,其最薄厚度可达6.8 nm,2DCoFeO表现出良好的OER性能,为2DTMOs电催化剂的可控合成开辟了新途径.此外,本文还分析了2DCoFeO电催化OER反应的机理,为二维电催化剂设计提供了新思路.

汽车环境舱流场的数值模拟与实验研究

采用实验方法研究了汽车环境舱在无车状态下的风速分布、边界层厚度、轴向静压梯度以及动压稳定性等流场特性;采用数值模拟方法建立1∶1的汽车环境舱模型,考虑环境舱内各种实验设施设备对流场的干扰效应,对环境舱内的流场分布进行了数值模拟。研究结果表明:汽车环境舱内的流场比较紊乱,试验段的流场呈现发散射流状态;主风机出口风速分布不均匀,最高风速与最低风速之间相差36 km/h;气流从风机流出后风速衰减明显,轴向静压梯度变化大;试验段内气流的边界层较厚,距离风机中心方向越远边界层厚度不断增大;数值仿真结果表明主风机的安装位置和尺寸对环境舱流场有一定影响,增大风机出风口的尺寸可以改善环境舱试验段的流场品质。

早熟机采棉品种中棉113在新疆引种示范表现及栽培技术要点

中棉113于2019年引种到北疆,在昌吉回族自治州和博尔塔拉蒙古自治州等地示范种植,平均666.7 m^(2)籽棉产量达到400 kg甚至更高,机采条件下多地多年的纤维上半部平均长度超过30 mm,断裂比强度超过30 cN·tex^(-1)。介绍了中棉113作为机采棉在北疆引种示范以来的特征特性表现及高产优质栽培技术要点,为新疆棉花的高产高效提供技术指导。

早熟棉花品种中7700(中棉所145)

中7700在西北内陆早熟棉区春播生育期123 d,株高67.05 cm,Ⅱ式果枝;抗枯萎病,耐黄萎病;2018―2019年西北内陆棉区早熟品种区域试验中,2年平均籽棉、皮棉和霜前皮棉产量分别为5380.5 kg·hm^(-2)、2272.5 kg·hm^(-2)和2250.0 kg·hm^(-2)。介绍了中7700的选育过程、特征特性及栽培技术要点。

电力调度系统广域分布式代理关键技术

随着电网一体化运行特征的日益显著,电力调度系统间业务数据交互愈加频繁。当前业务通过各自开发专用的网关程序进行数据传输难以满足未来调度业务的发展需求。本文提出了一种广域分布式代理技术,通过电力调度域名在各调度机构间感知广域分布式代理的位置信息,并结合广域链路复用、负载均衡和代理监控等功能,构建面向互联大电网调度业务的高效、通用的广域数据交互体系。广域分布式代理统一支撑多业务应用的广域数据传输需求、提高了数据传输规模、增强了系统可用性。广域分布式代理在数据传输规模和容错性等方面优势明显,能较好地适应未来电力调度大数据的传输要求。

基于单目深度估计的低功耗视觉里程计

随着人工智能、精密机械和计算技术的发展,微小型无人系统在未来战场上将会扮演重要的角色。为解决单目视觉里程计尺度缺失以及微型机器人自身体积和载荷限制带来的功耗问题,引入单目深度估计技术,构建了一个低视角数据集,通过搭建卷积神经网络从单张图像中预测深度信息,对神经网络模型进行结构优化,将深度估计与单目视觉里程计融合并部署到JetsonNano平台。实验表明,融合后的单目视觉里程计能够在特定环境下恢复尺度信息,在JetsonNano上的功耗能够保持在较低水平,可为微型无人系统在未来战场上的隐蔽化、轻量化部署提供一定的研究基础。

爆发式数据处理模型在电力调度系统中的应用

随着大型能源基地特高压项目的相继运行、新能源发电的深入推进和电动汽车等新型负荷的快速发展,电网监控爆发式海量数据的出现频率大幅增加,给电力调度监控和数据采集SCADA系统的数据管理带来了极大的挑战。文中分析了电力调度存储数据量大、随机性强的特点以及当前数据库抗压性能不稳定的现状,提出了爆发式数据处理模型EDPM(erupt data processing model),介绍了该模型下的多级缓存策略、基于模型控制器的自适应缓存管理机制、线程闭环控制自愈技术等关键技术。工程应用实践表明,EDPM模型在面对海量数据存储请求时仍可保持较快的系统响应和较高的系统吞吐量,能够有效抵御爆发式数据的冲击,保证电力调度SCADA系统的安全、稳定运行。

面向调控业务的多级一体化数据交换系统设计与实现

随着电网运行的一体化特征凸显,各级调控机构间的应用业务联系日趋紧密,对信息共享、数据交互的需求也越来越迫切。为了实现一体化协同运行,电网调控系统需要在不同调控机构和业务应用之间交互大量的实时数据和非实时数据。但目前的技术方案主要是面向实时业务之间的数据交互,缺少准实时/非实时业务场景下的通用数据交互机制。针对上述问题,提出了面向调控业务,实现准实时/非实时数据跨机构、跨安全区、跨平台的一体化交换体系架构,建立了规范的数据交互流程和基于任务的运行机制,实现了对数据交互过程的统一管理。目前研究成果已在工程中获得了实际应用,支撑了省调、地调和厂站的一体化协同业务。

Chinese multi-document personal name disambiguation

This paper presents a new approach to determining whether an interested personal name across doeuments refers to the same entity. Firstly,three vectors for each text are formed： the personal name Boolean vectors denoting whether a personal name occurs the text the biographical word Boolean vector representing title, occupation and so forth, and the feature vector with real values. Then, by combining a heuristic strategy based on Boolean vectors with an agglomeratie clustering algorithm based on feature vectors, it seeks to resolve multi-document personal name coreference. Experimental results show that this approach achieves a good performance by testing on ＂Wang Gang＂ corpus.

Prevention against diffuse spinal cord astrocytoma: can the Notch pathway be a novel treatment target?

This study was designed to investigate whether the Notch pathway is involved in the develop-ment of diffuse spinal cord astrocytomas. BALB/c nude mice received injections of CD133＋and CD133？ cell suspensions prepared using human recurrent diffuse spinal cord astrocytoma tissue through administration into the right parietal lobe. After 7–11 weeks, magnetic resonance imaging was performed weekly. Xenografts were observed on the surfaces of the brains of mice receiving the CD133＋ cell suspension, and Notch-immunopositive expression was observed in the xenografts. By contrast, no xenografts appeared in the identical position on the surfaces of the brains of mice receiving the CD133？ cell suspension, and Notch-immunopositive expres-sion was hardly detected either. Hematoxylin-eosin staining and immunohistochemical staining revealed xenografts on the convex surfaces of the brains of mice that underwent CD133＋ astro-cytoma transplantation. Some sporadic astroglioma cells showed pseudopodium-like structures, which extended into the cerebral white matter. However,it should be emphasized that the sub-cortex xenograft with Notch-immunopositive expression was found in the fourth mouse received injection of CD133？ astrocytoma cells. However, these ifndings suggest that the Notch pathway plays an important role in the formation of astrocytomas, and can be considered a novel treat-ment target for diffuse spinal cord astrocytoma.

UPLC-ESI-Q-TOF/MS法测定化妆品中倍他米松及其8种类似物

建立了同时分析倍他米松及其8种类似物的超高效液相色谱-高分辨质谱联用仪(UPLC-ESI-Q-TOF/MS)的定性、定量检测方法。采用小颗粒色谱柱,梯度洗脱,电喷雾离子源正离子模式(ESI+),利用TOF采集的化合物母离子推测分子组成,子离子推测结构,并借助对照品加以确证,利用质谱一级准分子离子建立含量测定方法。对建立的检测方法进行方法学验证,发现考察范围内线性关系良好,检出浓度为0.05~0.34 mg/kg,回收率为93.1%~103.7%,相对标准偏差普遍小于6%。在对10批化妆品的分析中,有5批检出激素,并首次发现了2种新的激素添加物:倍他米松17-丙酸酯、倍他米松21-丙酸酯。

Clinical and Imaging Analysis of a Cerebellar Watershed Infarction

Objective: To investigate the characteristics of vascular lesions in patients with a cerebellar watershed infarction. Methods: Clinical data from 178 cases of cerebellar infarction were collected with magnetic resonance imaging (MRI) scan results, including diffusion weighted imaging (DWI), a magnetic resonance angiography (MRA), and computed tomography angiography (CTA). The cases were divided into cerebellar watershed and non-watershed infarctions based on lesion location, which was revealed by DWI. Forty-two cases met the criteria for a cerebellar watershed infarction. Based on the MRA/CTA results, the vertebrobasilar artery stenoses were divided into four categories (i.e., intracranial, extracranial, combined, and no detectable stenosis) to compare the vascular lesion characteristics from patients with a cerebellar watershed infarction and patients with a non-watershed infarction. Results: Patients with cerebellar watershed infarcts presented mild symptoms at onset and had a favorable prognosis. However, 90.5% of these patients had a vascular stenosis, which was higher than for patients with a cerebellar non-watershed infarction (74.3%). The four types of vascular lesions, intracranial, extracranial, combined, and no detectable stenosis, were 14.3%, 52.4%, 23.8%, and 9.5% in patients with a cerebellar watershed infarction and 33.8%, 16.2%, 24.3%, and 25.7% in patients with a non-watershed cerebellar infarction, respectively. Conclusion: Although patients with cerebellar watershed infarcts often had comparatively benign clinical manifestations and prognoses, such patients also had a high stenosis prevalence in major blood vessels, especially the extracranial segment in the vertebral artery, which required early intervention and treatment.