Despite the various synthesis approachs to obtain luminous carbon dots(CDs),it is still quite challenging to construct the efficient electrochemiluminescence(ECL)owing to their low ECL reactivity and easy agglomeratio...Despite the various synthesis approachs to obtain luminous carbon dots(CDs),it is still quite challenging to construct the efficient electrochemiluminescence(ECL)owing to their low ECL reactivity and easy agglomeration.Herein,an efficient and concise ECL system was skillfully constructed by taking advantage of the nitrogen and sulfur co-doped CDs(N,S-CDs)with surfaces rich in hydrazide groups as luminophors to emit intense ECL,and metal-organic framework(MOF)as the matrix to confine CDs in its nanospace.Surprisingly,the proposed CDs assembled MOF(CDs/ZIF-8)enhanced anodic ECL signal up to 250%of pure CDs under the exogenous coreactant-free condition.As a proof of concept,the highly sensitive detection of uric acid(UA)was realized by the constructed ECL platform with a low detection limit of 3.52 nmol/L ranging from 10 nmol/L to 50μmol/L.This work expanded ideas for the application of pore confinement effect,and provided references for the detection of disease biomarkers of gout and hyperuricemia.展开更多
基金financially supported by the NNSF of China(No.22022408)the Chongqing Talents Personnel Support Program(No.CQYC201905067)the Fundamental Research Funds for the Central Universities(No.XDJK2019TJ002)。
文摘Despite the various synthesis approachs to obtain luminous carbon dots(CDs),it is still quite challenging to construct the efficient electrochemiluminescence(ECL)owing to their low ECL reactivity and easy agglomeration.Herein,an efficient and concise ECL system was skillfully constructed by taking advantage of the nitrogen and sulfur co-doped CDs(N,S-CDs)with surfaces rich in hydrazide groups as luminophors to emit intense ECL,and metal-organic framework(MOF)as the matrix to confine CDs in its nanospace.Surprisingly,the proposed CDs assembled MOF(CDs/ZIF-8)enhanced anodic ECL signal up to 250%of pure CDs under the exogenous coreactant-free condition.As a proof of concept,the highly sensitive detection of uric acid(UA)was realized by the constructed ECL platform with a low detection limit of 3.52 nmol/L ranging from 10 nmol/L to 50μmol/L.This work expanded ideas for the application of pore confinement effect,and provided references for the detection of disease biomarkers of gout and hyperuricemia.
