Meta-analysis of randomized controlled trials of acupuncture in the treatment of menopausal insomnia

Objective:We aimed to investigate the safety and efficacy of acupuncture in the treatment of climacteric insomnia compared with western medicine through a comprehensive metaanalysis.Methods:Literature retrieval,research selection and data extraction were done independently and in duplicate.Effect-size estimates are expressed as risk ratio(RR)and 95%confidence interval(CI).Results:Summary data from 27 articles,involving a total of 2349 menopausal women,were meta-analyzed.The overall analysis showed that the clinical cure rate(RR=1.85,95%CI:1.57~2.18,P<0.001)of acupuncture was 1.85 times higher than western medicine,and the markedly effective rate was 1.3 times higher than that of westernmedicine(RR=1.30,95%CI:1.09~1.54,P=0.003).In terms of Pittsburgh Sleep quality Index((PSQI)),simple acupuncture is superior to western medicine in sleep quality,falling asleep time,sleep time,sleep efficiency and daytime dysfunction.In the evaluation of adverse reactions,the incidence of adverse events in the acupuncture-related therapy group(3.5%)was lower than that in the western medicine group(12.5%).Conclusion:The results of metaanalysis show that the clinical efficacy of acupuncture in the treatment of climacteric insomnia is better than that of western medicine which has better efficacy and safety.The acupuncture therapy is suitable for clinical.

Relationship between nap and hypertension in adults: An updated meta-analysis

Objective:We aimed to investigate whether nap is associated with an increased risk of hypertension through a comprehensive meta-analysis.Methods:Literature retrieval,research selection and data extraction were done independently and in duplicate.Effect-size estimates are expressed as risk ratio(RR)and 95%confidence interval(CI).Results:Summary data from 13 articles,involving a total of 119501 adults,were meta-analyzed.The overall analysis showed that in the included articles,when the factors were not adjusted,there was a significant association between nap and hypertension(RR=1.11,95%CI:1.02 to 1.21,P=0.013).After adjusting the possible confounding factors,nap was still correlated with hypertension(RR=1.07,95%CI:1.01 to 1.14,P=0.041).In the subgroup analysis,there was a significant association between nap and hypertension in women(RR=1.13,95%CI:1.04 to 1.22,P=0.004),but this relationship was not recurred in men.And there was a significant association between nap and hypertension in people 45 years old(RR=1.16,95%CI:1.08 to 1.24,P<0.001).In the dose analysis,it was found that there was a significant association between high blood pressure and the population with nap duration 90 minutes(RR=1.13,95%CI:1.01 to 1.27,P=0.04).Conclusion:Our meta-analysis results show that nap is a risk factor for hypertension,which is more obvious in women,and the difference is statistically significant.In the elderly people,nap is a protective factor for hypertension.