The national independent innovation demonstration zone(NIIDZ)is an independent innovation policy that plays a crucial role in implementing strategies.Given the importance of the NIIDZ,this study uses panel data of 278...The national independent innovation demonstration zone(NIIDZ)is an independent innovation policy that plays a crucial role in implementing strategies.Given the importance of the NIIDZ,this study uses panel data of 278 prefecture-level cities in China from 2006 to 2020 and empirically examines the effect and internal mechanism of the NIIDZ on green economic efficiency(GEE)using the difference-in-difference model(DID).The results show that the NIIDZ effectively enhances the growth of GEE,and the results remain valid through several robustness tests,such as year-by-year propensity score matching.The transmission mechanism suggests that the NIIDZ indirectly drives GEE by accelerating scientific and technological investment,promoting talent concentration,and optimizing the industrial structure.Moreover,heterogeneity analysis reveals that the promotion effect of the NIIDZ on GEE is more prominent in the eastern region and high green development level areas.The study’s findings can serve as a reference for China to further utilize the policy effectiveness of the NIIDZ and accelerate the high-quality development of the green economy in the future.展开更多
[Objectives]To determine the content of total saponins in Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S.kurita,fill the gap in the study of Paris daliensis H. Li et V. G. Soukoup and Paris du...[Objectives]To determine the content of total saponins in Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S.kurita,fill the gap in the study of Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S. kurita,and lay a foundation for searching new medicinal resources of Paris L. [Methods]The perchloric acid colorimetric method and UV spectrophotometer were used to determine the content of total saponins in Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S. kurita at 406 nm. [Results]The lowest content of total saponins in Paris daliensis H. Li et V. G. Soukoup was 2. 637%,while the highest content reached 5. 474%; the lowest content of total saponins in Paris dulongensis was 1. 806%,while the highest content reached 3. 532%. Through the methodological examination,it was found that this method was stable and reliable. [Conclusions] The content of total saponins was high in Paris daliensis H.Li et V. G. Soukoup and Paris dulongensis H. Li et S. kurita,and it was suggested to further study and find the medicinal resources of Paris L.展开更多
[Objectives]To study content of total saponins from cultivated and wild Paris herbs in Southwest China,evaluate its in vitro antioxidation activity,and explore the correlation between quality of Paris herbs and produc...[Objectives]To study content of total saponins from cultivated and wild Paris herbs in Southwest China,evaluate its in vitro antioxidation activity,and explore the correlation between quality of Paris herbs and production place,variety,cultivated and wild varieties.[Methods]Colorimetric method of perchloric acid reaction was used,and content of total saponins from Paris herbs was determined by ultraviolet spectrophotometer at 406 nm. [Results]The lowest content of total saponins from cultivated and wild Paris herbs in Southwest China was0. 55%,while the maximum was 12. 24%,with obvious difference. Total saponins from Paris herbs had stronger clearance ability on free radical DPPH and stronger reduction ability on Fe^(3+),and the results showed good dose-effect relationship with concentration. Among them,S6 had the highest clearance ability on DPPH,which reached 89. 66%. In the determination of reduction ability,the absorbance of S16 reached3. 643 and was the highest,with very good reducing property. Content and anti-oxidation capacity of total saponins from Paris herbs in Southwest China did not have obvious correlation with production place,altitude and cultivation but was related to variety. [Conclusions]The quality of Paris herbs in Southwest China was unstable,and their anti-oxidation abilities were also different,and cultivation could not guarantee high quality. It should normalize cultivation,and develop planting industry of Paris herbs,which could guarantee stable supply of Paris herbs and stability and controllability of quality.展开更多
Mengjie Yu:Hello,everyone.This interview is organized by the journal Advanced Photonics.And today we're really honored and privileged to have Professor Jelena Vuckovic from Stanford University here with us.I'm...Mengjie Yu:Hello,everyone.This interview is organized by the journal Advanced Photonics.And today we're really honored and privileged to have Professor Jelena Vuckovic from Stanford University here with us.I'm from University of Southern California and will conduct the interview.展开更多
The thyroid is an essential endocrine organ in human body,and thyroid hormones(THs)are pivotal signaling molecules and mediators in various physiological processes.THs,particularly in their free form,play a critical r...The thyroid is an essential endocrine organ in human body,and thyroid hormones(THs)are pivotal signaling molecules and mediators in various physiological processes.THs,particularly in their free form,play a critical role in regulating body temperature and in the metabolism of lipid and glucose,making the maintenance of TH levels crucial for human health.THs undergo a series of metabolic processes,producing TH metabolites(THMs).THMs are significant in endocrine regulation,such as 3,5-diiothyronine(3,5-T2)and 3-iodothyronamine(3-T1AM),which exhibit activities akin to THs.The production and distribution of THMs are intricately linked to the function of specific organs and tissues,highlighting the need for advanced research into the determination and mechanisms of THMs in body.Exposure to endocrine disrupting chemicals(EDCs)can significantly affect the levels of thyroid stimulating hormone(TSH)and THs.This review utilizes machine learning to analyze epidemiological data,identifying potential EDCs that pose risks of hyperthyroidism and hypothyroidism.Additionally,it delves into the toxicological mechanisms of these EDCs,examining their effects on TH production,binding processes,related proteins,and metabolic enzymes.This approach effectively bridges the gap between epidemiological studies and toxicological researches,laying the groundwork for future research trends.By integrating epidemiological studies with machine learning,this review offers insightful perspectives on the potential risks associated with chemical exposure and underscores the necessity for further research in understanding the impact of EDCs on TH metabolism and TH-related health effects.展开更多
Optical microresonators,which confine light in both the spatial and time domains,have advanced various research areas benefiting from significantly enhanced light-matter interactions,including integrated microlasers,n...Optical microresonators,which confine light in both the spatial and time domains,have advanced various research areas benefiting from significantly enhanced light-matter interactions,including integrated microlasers,nonlinear frequency conversion,Kerr frequency combs,and optomechanics.Over the past five years,the research interests in optical microresonators have rapidly expanded and combined with other disciplines,for example,optical chaos,non-Hermitian physics,and quantum materials.These cutting-edge research works have enabled the creation of optical microresonators with novel properties and capabilities.展开更多
The recent advancement in lithium-niobite-on-insulator(LNOI)technology is opening up new opportunities in optoelectronics,as devices with better performance,lower power consumption and a smaller footprint can be reali...The recent advancement in lithium-niobite-on-insulator(LNOI)technology is opening up new opportunities in optoelectronics,as devices with better performance,lower power consumption and a smaller footprint can be realised due to the high optical confinement in the structures.The LNOI platform offers both largeχ(2)andχ(3)nonlinearities along with the power of dispersion engineering,enabling brand new nonlinear photonic devices and applications for the next generation of integrated photonic circuits.However,Raman scattering and its interaction with other nonlinear processes have not been extensively studied in dispersion-engineered LNOI nanodevices.In this work,we characterise the Raman radiation spectra in a monolithic lithium niobate(LN)microresonator via selective excitation of Raman-active phonon modes.The dominant mode for the Raman oscillation is observed in the backward direction for a continuous-wave pump threshold power of 20mW with a high differential quantum efficiency of 46%.We explore the effects of Raman scattering on Kerr optical frequency comb generation.We achieve mode-locked states in an X-cut LNOI chip through sufficient suppression of the Raman effect via cavity geometry control.Our analysis of the Raman effect provides guidance for the development of future chip-based photonic devices on the LNOI platform.展开更多
Manipulating the frequency and bandwidth of nonclassical light is essential for implementing frequency-encoded/multiplexed quantum computation,communication,and networking protocols,and for bridging spectral mismatch ...Manipulating the frequency and bandwidth of nonclassical light is essential for implementing frequency-encoded/multiplexed quantum computation,communication,and networking protocols,and for bridging spectral mismatch among various quantum systems.However,quantum spectral control requires a strong nonlinearity mediated by light,microwave,or acoustics,which is challenging to realize with high efficiency,low noise,and on an integrated chip.Here,we demonstrate both frequency shifting and bandwidth compression of heralded single-photon pulses using an integrated thin-film lithium niobate(TFLN)phase modulator.We achieve record-high electro-optic frequency shearing of telecom single photons over terahertz range(±641 GHz or±5.2 nm),enabling high visibility quantum interference between frequency-nondegenerate photon pairs.We further operate the modulator as a time lens and demonstrate over eighteen-fold(6.55 nm to 0.35 nm)bandwidth compression of single photons.Our results showcase the viability and promise of on-chip quantum spectral control for scalable photonic quantum information processing.展开更多
基金supported by the National Natural Science Foundation of China[Grant No.72163018]the Yunnan College Students’Innovation and Entrepreneurship Training Program[Grant No.S202310674173]the Yunnan Province Basic Research Program General Project[Grant No.202401AT070393].
文摘The national independent innovation demonstration zone(NIIDZ)is an independent innovation policy that plays a crucial role in implementing strategies.Given the importance of the NIIDZ,this study uses panel data of 278 prefecture-level cities in China from 2006 to 2020 and empirically examines the effect and internal mechanism of the NIIDZ on green economic efficiency(GEE)using the difference-in-difference model(DID).The results show that the NIIDZ effectively enhances the growth of GEE,and the results remain valid through several robustness tests,such as year-by-year propensity score matching.The transmission mechanism suggests that the NIIDZ indirectly drives GEE by accelerating scientific and technological investment,promoting talent concentration,and optimizing the industrial structure.Moreover,heterogeneity analysis reveals that the promotion effect of the NIIDZ on GEE is more prominent in the eastern region and high green development level areas.The study’s findings can serve as a reference for China to further utilize the policy effectiveness of the NIIDZ and accelerate the high-quality development of the green economy in the future.
基金Supported by Sichuan Science and Technology Support Program(2016FZ-0045)Education and Teaching Research and Reform Project of Southwest University for Nationalities(2015)
文摘[Objectives]To determine the content of total saponins in Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S.kurita,fill the gap in the study of Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S. kurita,and lay a foundation for searching new medicinal resources of Paris L. [Methods]The perchloric acid colorimetric method and UV spectrophotometer were used to determine the content of total saponins in Paris daliensis H. Li et V. G. Soukoup and Paris dulongensis H. Li et S. kurita at 406 nm. [Results]The lowest content of total saponins in Paris daliensis H. Li et V. G. Soukoup was 2. 637%,while the highest content reached 5. 474%; the lowest content of total saponins in Paris dulongensis was 1. 806%,while the highest content reached 3. 532%. Through the methodological examination,it was found that this method was stable and reliable. [Conclusions] The content of total saponins was high in Paris daliensis H.Li et V. G. Soukoup and Paris dulongensis H. Li et S. kurita,and it was suggested to further study and find the medicinal resources of Paris L.
基金Supported by Sichuan Science and Technology Support Plan(2016FZ0045)Sichuan Key Technology Innovation Project Plan(2014XM041)Research and Development Fund of Application Technology in Aba Prefecture(2015)
文摘[Objectives]To study content of total saponins from cultivated and wild Paris herbs in Southwest China,evaluate its in vitro antioxidation activity,and explore the correlation between quality of Paris herbs and production place,variety,cultivated and wild varieties.[Methods]Colorimetric method of perchloric acid reaction was used,and content of total saponins from Paris herbs was determined by ultraviolet spectrophotometer at 406 nm. [Results]The lowest content of total saponins from cultivated and wild Paris herbs in Southwest China was0. 55%,while the maximum was 12. 24%,with obvious difference. Total saponins from Paris herbs had stronger clearance ability on free radical DPPH and stronger reduction ability on Fe^(3+),and the results showed good dose-effect relationship with concentration. Among them,S6 had the highest clearance ability on DPPH,which reached 89. 66%. In the determination of reduction ability,the absorbance of S16 reached3. 643 and was the highest,with very good reducing property. Content and anti-oxidation capacity of total saponins from Paris herbs in Southwest China did not have obvious correlation with production place,altitude and cultivation but was related to variety. [Conclusions]The quality of Paris herbs in Southwest China was unstable,and their anti-oxidation abilities were also different,and cultivation could not guarantee high quality. It should normalize cultivation,and develop planting industry of Paris herbs,which could guarantee stable supply of Paris herbs and stability and controllability of quality.
文摘Mengjie Yu:Hello,everyone.This interview is organized by the journal Advanced Photonics.And today we're really honored and privileged to have Professor Jelena Vuckovic from Stanford University here with us.I'm from University of Southern California and will conduct the interview.
基金funded by the National Natural Science Foundation of China(42277425,42161134001,U22A20614)“the Fundamental Research Funds for the Central Universities”,Nankai University(63171109)+4 种基金sponsored by Tianjin Health Research Project(TJWJ2023MS028)Tianjin Science and Technology planning project(21JCZDJC00330)National Clinical Key Discipline Cohort Study Project(GJZDZKZBDL 2022-)Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-043A)Ministry of Education,China(T2017002).
文摘The thyroid is an essential endocrine organ in human body,and thyroid hormones(THs)are pivotal signaling molecules and mediators in various physiological processes.THs,particularly in their free form,play a critical role in regulating body temperature and in the metabolism of lipid and glucose,making the maintenance of TH levels crucial for human health.THs undergo a series of metabolic processes,producing TH metabolites(THMs).THMs are significant in endocrine regulation,such as 3,5-diiothyronine(3,5-T2)and 3-iodothyronamine(3-T1AM),which exhibit activities akin to THs.The production and distribution of THMs are intricately linked to the function of specific organs and tissues,highlighting the need for advanced research into the determination and mechanisms of THMs in body.Exposure to endocrine disrupting chemicals(EDCs)can significantly affect the levels of thyroid stimulating hormone(TSH)and THs.This review utilizes machine learning to analyze epidemiological data,identifying potential EDCs that pose risks of hyperthyroidism and hypothyroidism.Additionally,it delves into the toxicological mechanisms of these EDCs,examining their effects on TH production,binding processes,related proteins,and metabolic enzymes.This approach effectively bridges the gap between epidemiological studies and toxicological researches,laying the groundwork for future research trends.By integrating epidemiological studies with machine learning,this review offers insightful perspectives on the potential risks associated with chemical exposure and underscores the necessity for further research in understanding the impact of EDCs on TH metabolism and TH-related health effects.
文摘Optical microresonators,which confine light in both the spatial and time domains,have advanced various research areas benefiting from significantly enhanced light-matter interactions,including integrated microlasers,nonlinear frequency conversion,Kerr frequency combs,and optomechanics.Over the past five years,the research interests in optical microresonators have rapidly expanded and combined with other disciplines,for example,optical chaos,non-Hermitian physics,and quantum materials.These cutting-edge research works have enabled the creation of optical microresonators with novel properties and capabilities.
基金supported by the National Science Foundation under NSF ECCS award No.1541959supported by the National Science Foundation(NSF)(ECCS-1740296 E2CDA)+1 种基金Defense Advanced Research Projects Agency(DARPA)(W31P4Q-15-1-0013)Air Force Office of Scientific Research(AFOSR)(FA9550-15-1-0303).
文摘The recent advancement in lithium-niobite-on-insulator(LNOI)technology is opening up new opportunities in optoelectronics,as devices with better performance,lower power consumption and a smaller footprint can be realised due to the high optical confinement in the structures.The LNOI platform offers both largeχ(2)andχ(3)nonlinearities along with the power of dispersion engineering,enabling brand new nonlinear photonic devices and applications for the next generation of integrated photonic circuits.However,Raman scattering and its interaction with other nonlinear processes have not been extensively studied in dispersion-engineered LNOI nanodevices.In this work,we characterise the Raman radiation spectra in a monolithic lithium niobate(LN)microresonator via selective excitation of Raman-active phonon modes.The dominant mode for the Raman oscillation is observed in the backward direction for a continuous-wave pump threshold power of 20mW with a high differential quantum efficiency of 46%.We explore the effects of Raman scattering on Kerr optical frequency comb generation.We achieve mode-locked states in an X-cut LNOI chip through sufficient suppression of the Raman effect via cavity geometry control.Our analysis of the Raman effect provides guidance for the development of future chip-based photonic devices on the LNOI platform.
基金supported by Harvard Quantum Initiative(HQI),ARO/DARPA(W911NF2010248),AFOSR(FA9550-20-1-01015),DARPA LUMOS(HR0011-20-C-0137),DOE(DE-SC0020376),NSF(EEC-1941583,ECCS-1839197),and AFRL(FA9550-21-1-0056)support by HQI post-doctoral fellowship and A*STAR SERC Central Research Fund(CRF)support by the AQT Intelligent Quantum Networks and Technologies(INQNET)research program.
文摘Manipulating the frequency and bandwidth of nonclassical light is essential for implementing frequency-encoded/multiplexed quantum computation,communication,and networking protocols,and for bridging spectral mismatch among various quantum systems.However,quantum spectral control requires a strong nonlinearity mediated by light,microwave,or acoustics,which is challenging to realize with high efficiency,low noise,and on an integrated chip.Here,we demonstrate both frequency shifting and bandwidth compression of heralded single-photon pulses using an integrated thin-film lithium niobate(TFLN)phase modulator.We achieve record-high electro-optic frequency shearing of telecom single photons over terahertz range(±641 GHz or±5.2 nm),enabling high visibility quantum interference between frequency-nondegenerate photon pairs.We further operate the modulator as a time lens and demonstrate over eighteen-fold(6.55 nm to 0.35 nm)bandwidth compression of single photons.Our results showcase the viability and promise of on-chip quantum spectral control for scalable photonic quantum information processing.