Pre-donation evaluation of organ donors is important.Organ quality directly affects both short-and long-term survival rates of transplanted organs and recipients after transplantation.Contraindications to donation are...Pre-donation evaluation of organ donors is important.Organ quality directly affects both short-and long-term survival rates of transplanted organs and recipients after transplantation.Contraindications to donation are directly related to recipient survival and medical ethics.The following information is included in this organ donation case report:detailed medical history(primary disease and surgical history),blood type,infectious diseases,coagulation function,biochemical function,tumor biomarker,indicators related to tuberculosis infection,microbial culture indicators,lung computed tomography(CT)scan,and abdominal ultrasound(heart,liver,gallbladder,pancreas,spleen,kidneys,ureters,bladder,adnexa).We found a 10 cm×10 cm space-occupying lesion in the abdominal cavity in this donor organ retrieval surgery.Frozen or paraffin sections showed that the space-occupying lesion was malignant.The organ donor was not suitable due to the malignant tumor,and the transplantation surgery was canceled.We analyzed this case of organ donation to provide a reference for the follow-up donation evaluation process.This case study reveals the limitations of preoperative non-invasive assessment,the necessity of preoperative multi-dimensional assessment of organ function,and the exclusion of donation contraindications.展开更多
基金Supported by grants from the National Natural Sciences Foundation of China(No.81800580)Wuhan Federation of Social Sciences(No.WHSKL2020140)the Sichuan Medical Law Research Center(No.YF20-Y05)。
文摘Pre-donation evaluation of organ donors is important.Organ quality directly affects both short-and long-term survival rates of transplanted organs and recipients after transplantation.Contraindications to donation are directly related to recipient survival and medical ethics.The following information is included in this organ donation case report:detailed medical history(primary disease and surgical history),blood type,infectious diseases,coagulation function,biochemical function,tumor biomarker,indicators related to tuberculosis infection,microbial culture indicators,lung computed tomography(CT)scan,and abdominal ultrasound(heart,liver,gallbladder,pancreas,spleen,kidneys,ureters,bladder,adnexa).We found a 10 cm×10 cm space-occupying lesion in the abdominal cavity in this donor organ retrieval surgery.Frozen or paraffin sections showed that the space-occupying lesion was malignant.The organ donor was not suitable due to the malignant tumor,and the transplantation surgery was canceled.We analyzed this case of organ donation to provide a reference for the follow-up donation evaluation process.This case study reveals the limitations of preoperative non-invasive assessment,the necessity of preoperative multi-dimensional assessment of organ function,and the exclusion of donation contraindications.
