进城务工人员和商务人士出行方式选择的影响因素与差异分析—以铁路提速提价为背景

近十年来,我国的铁路行业发展迅速,为人们的出行提供了更多的选择。文章研究在铁路提速提价的背景下,进城务工人员与商务人士选择出行方式的影响因素与差异分析。主要采用文献阅读、问卷调查和访谈的方法进行研究。研究发现,耗用时长是二者共同关注的因素,但是商务人士更注重舒适度,对价格不太敏感,而后者正好相反,这些差异导致了二者选择出行方式的差异:商务人士出行多乘用高铁,而进城务工人员出行选用普通火车的比例更高。

Environmental parameter estimation with the two-level atom probes

A novel scheme is proposed to estimate three environmental parameters,the detuning,the temperature and the squeezing strength with one-qubit or two-qubit probes.Quantum Fisher information and the fidelity of the atom probes are calculated.When the detuning between the frequency of cavity field and the atomic transition frequency is estimated,the dynamics of quantum Fisher information shows oscillatory and rising behaviors.To estimate the temperature of the thermal reservoir,the one-qubit probe with the superposition initial state is more favorable than the two-qubit probe with the entangled initial state.When the squeezing strength of the squeezed vacuum reservoir is estimated,we find that the estimation precision is significantly improved by utilizing the two-qubit probe with the maximal entangled initial state.Our work provides a potential application in the open quantum system and quantum information processing.

High-precision three-dimensional atom localization via probe absorption at room temperature

A scheme is used to explore the behavior of three-dimensional(3D)atom localization in a Y-type hot atomic system.We can obtain the position information of the atom due to the position-dependent atom–field interaction.We study the influences of the system parameters and the temperature on the atom localization.More interestingly,the atom can be localized in a subspace when the temperature is equal to 323 K.Moreover,a method is proposed to tune multiparameter for localizing the atom in a subspace.The result is helpful to achieve atom nanolithography,photonic crystal and measure the center-of-mass wave function of moving atoms.

Three-Dimensional M-Shaped Resection for Nasal Alar Hypertrophy in Asian Patients

Background Nasal alarplasty is an important component of esthetic rhinoplasty in Asians.The two main surgical techniques that correct alar hypertrophy by reducing the height or length often leave external scars and are associated with a high relapse rate.Methods We developed a new technique,called three-dimensional(3D)M-shaped resection,which corrects both the nasal alar height and length and simultaneously minimizes external scarring.We performed this procedure from January 2013 to September 2016 in 49 consecutive female patients diagnosed with saddle nose and nasal alar hypertrophy.Their mean age was 28.6(range,18–40)years.All patients had previously undergone simple rhinoplasty.Nasal alar length and height,nostril length and width,and maximal nose width were analyzed preoperatively and postoperatively from photographs.Results After a mean of 9(range,3–24)months of follow-up,surgery was considered successful in 46 women(94%)with good cosmetic effects.In three patients,nasal alar hypertrophy recurred(6 months postoperatively).There were no early complications such as hematomas,infections,skin or mucosal necrosis,or wound dehiscence.The mean reductions postoperatively were 1.7 mm and 0.9 mm for nasal alar length and height,respectively,1.6 mm for both nostril length and width,and 3.5 mm for nose width.Conclusion The 3D M-shaped resection for nasal alar hypertrophy effectively reduced hypertrophy in 94%of patients for up to 24 months,producing minimal external scars and good cosmetic effects.It is a simple and convenient technique that is an effective and safe option for nasal alarplasty.

Efficiency against multidrug resistance by co-delivery of doxorubicin and curcumin with a legumain-sensitive nanocarrier

Multidrug resistance proteins （MDRPs）, which are implicated in the mediation of multidrug resistance in tumors, represent the main obstacle to successful chemotherapy. As curcurnin （Cur） exerts inhibitory effects on both the expression and function of MDRPs, a nanocarrier for the co-delivery of Cur and doxorubicin （DOX） was prepared to overcome MDR tumors through their synergistic effects. Owing to the overexpression of legumain in tumors, the release profile of DOX from this nanocarrier was designed to be legumain modulated, which was achieved by bridging DOX to a basic material （chitosan） with a legumain- sensitive peptide. Compared with nanoparticles that only contain DOX, the coadministration of DOX and Cur significantly inhibited multidrug resistance （P 〈 0.05） in a multidrug-resistant cancer cell model （MCF-7/ADR cell line）, with cytotoxicity to normal cells （L929 cell line）. Such inhibition could be ascribed to the increased DOX accumulation in the MCF-7/ADR nucleus. The co-delivery system exhibited good anticancer effects through prolonged circulation time, improved tumor-targeting efficiency, elevation of the tumor inhibition activity, and the suppression of MDRP expression. These data revealed the enormous potential of this co-delivery system for cancer therapy, especially in the later stages where multidrug resistance may develop.