Whispering Gallery Mode Lasing Performance's Evolution of Floating GaN Microdisks Varying with Their Thickness

Optical gain and loss of microcavity greatly affect the quality of lasing,how to improve optical gain and decrease optical loss is of great significance for the preparation of laser.In this study,four types standard microdisks with different thicknesses of 2.2μm,1.9μm,1.7μm,and 1.45μm were fabricated by micromachining technology process to modulate optical gain and loss of microdisk lasing.The whispering gallery mode lasing in the ultraviolet range of Ga N microdisk devices was investigated for these devices in order to clarify the effect of microdisk thickness on device characteristics.The quality factor Q and lasing mode number for different thicknesses are calculated from the stimulated spectra.The lifetimes of the exciton combination properties of the devices were observed using time-resolved PL spectroscopy.The lasing modes are modulated,and the lifetime decreases,while the Q factor of the devices first increases and then decreases with decreasing thickness.All these results are induced by optical gain and loss competition.

Screen-printing of Bi2S3 Nanowires on Silk Fabrics for the Construction of Flexible Optical Switch

Wearable electronics has been one of the hottest research topics in recent years and fabric is regarded as a very promising substrate for the wearable units because of its excellent wearability.So far,there is no report on the construction of a fabric-based optical switch.In the present work we fabricate a silk fabric-based optical switch via screen-printing of silver interdigital electrode and Bi2S3 nanowires network layer.Bi2S3 NWs with

Nano-functionalized Silk for Smart Wearable Devices

With rapid advances of miniaturization and wireless technologies,electronics has been associated with traditional textiles to develop smart wearable devices for daily health monitoring and fitness tracking 1-2.It is of great demand to fabricate flexible materials that possess both wearability and prac-

Silk-based Flexible Solid State Supercapacitor Preparedby Screen-Printingfor Wearable Applications

Flexible supercapacitors have attracted much attention owing to their great potentials in wearable electronics.However,flexible solid state supercapacitor with silk fabric as the supporting substrate has not been realized.In this work,a simple and low-cost method is introduced to fabricate flexible solid-state supercapacitors on silk fabric via

Novel biomarkers identifying hypertrophic cardiomyopathy and its obstructive variant based on targeted amino acid metabolomics

Background:Hypertrophic cardiomyopathy(HCM)is an underdiagnosed genetic heart disease worldwide.The management and prognosis of obstructive HCM(HOCM)and non-obstructive HCM(HNCM)are quite different,but it also remains challenging to discriminate these two subtypes.HCM is characterized by dysmetabolism,and myocardial amino acid(AA)metabolism is robustly changed.The present study aimed to delineate plasma AA and derivatives profiles,and identify potential biomarkers for HCM.Methods:Plasma samples from 166 participants,including 57 cases of HOCM,52 cases of HNCM,and 57 normal controls(NCs),who first visited the International Cooperation Center for HCM,Xijing Hospital between December 2019 and September 2020,were collected and analyzed by high-performance liquid chromatography-mass spectrometry based on targeted AA metabolomics.Three separate classification algorithms,including random forest,support vector machine,and logistic regression,were applied for the identification of specific AA and derivatives compositions for HCM and the development of screening models to discriminate HCM from NC as well as HOCM from HNCM.Results:The univariate analysis showed that the serine,glycine,proline,citrulline,glutamine,cystine,creatinine,cysteine,choline,and aminoadipic acid levels in the HCM group were significantly different from those in the NC group.Four AAs and derivatives(Panel A;proline,glycine,cysteine,and choline)were screened out by multiple feature selection algorithms for discriminating HCM patients from NCs.The receiver operating characteristic(ROC)analysis in Panel A yielded an area under the ROC curve(AUC)of 0.83(0.75-0.91)in the training set and 0.79(0.65-0.94)in the validation set.Moreover,among 10 AAs and derivatives(arginine,phenylalanine,tyrosine,proline,alanine,asparagine,creatine,tryptophan,ornithine,and choline)with statistical significance between HOCM and HNCM,3 AAs(Panel B;arginine,proline,and ornithine)were selected to differentiate the two subgroups.The AUC values in the training and validation sets for Panel B were 0.83(0.74-0.93)and 0.82(0.66-0.98),respectively.Conclusions:The plasma AA and derivatives profiles were distinct between the HCM and NC groups.Based on the differential profiles,the two established screening models have potential value in assisting HCM screening and identifying whether it is obstructive.