Background: Idiopathic epiretinal membranes (ERM) grow on the surface of the i nternal limiting membrane (ILM) and are a very uncommon condition in young subje cts. Methods: We report six young subjects withERM and de...Background: Idiopathic epiretinal membranes (ERM) grow on the surface of the i nternal limiting membrane (ILM) and are a very uncommon condition in young subje cts. Methods: We report six young subjects withERM and describe the spontaneous separation of the membranes. The functional and anatomical recovery was assessed by Snellen visual acuity, Amsler grid and funduscopy. Selected cases were addit ionally assessed by optical coherence tomography (OCT). Results: All subjects in itially claimed a sudden, unilateral, reduction in visual acuity (VA) with sever e distortion at the age of 15-30 years. No ocular trauma or disease was ascerta ined in any case. Initial fundus examination demonstrated a gray-whitish ERM wi th translucent stress lines over the macula. Visual recovery occurred in all cas es after resolution of the ERM. Sequential OCT demonstrated the successive peeli ng of an ERM accompanied by normalization of foveal thickness. Conclusions: Youn g subjects should b e counseled about the favorable prognosis for maintaining go od vision and possible spontaneous membrane separation. Conservative observation is advocated if the visual disturbance is located temporally, as functional rec overy and spontaneous membrane separation may occur. When the contracting forces of the immature ERM are stronger than its adhesions to the retina, the membrane may separate spontaneously.展开更多
Purpose: To describe photodynamic therapy (PDT) and additional indocyanine green (ICG) guided feeder vessel pho-tocoagulation as a treatment of choroidal neovascularization (CNV) secondary to choroidal rupture in case...Purpose: To describe photodynamic therapy (PDT) and additional indocyanine green (ICG) guided feeder vessel pho-tocoagulation as a treatment of choroidal neovascularization (CNV) secondary to choroidal rupture in case of blunt head trauma. Design: Interventional case report. Methods: A 61- year-old woman developed subfoveal CNV originating from a choroid tear 8 years after blunt head trauma. Four sessions of PDT were applied and an additional two consecutive sessions of selective ICG-guided feeder vessel photocoagulation conducted. Results: Transient reduction of leakage and closure of feeder vessels could not prevent further growth of the CNV. Conclusions: PDT reduced leakage temporarily and additional ICG-guided feeder vessel photocoagulation closed treated feeder vessel and CNV. Newfeeder vessel formation and growth of CNV in case of traumatic choroid rupture could not be treated effectively by these two laser treatment modalities to prevent severe deterioration of visual acuity.展开更多
To investigate image preferences after photodynamic therapy (PDT). Prospective, cross-sectional study. Seventeen patients with neovascular age-related macular degeneration were tested by color vision, contrast sensiti...To investigate image preferences after photodynamic therapy (PDT). Prospective, cross-sectional study. Seventeen patients with neovascular age-related macular degeneration were tested by color vision, contrast sensitivity, and near visual acuity (VA)-with positive images and negative images before, 1 week after, and 3 months after PDT. Before PDT, 13 patients (76% ) preferred positive images; the difference was not significant (P < .04). One week after PDT, 16 patients (94% ) preferred negative images. The average near VA improved to 27 letters on positive images and to32 letters on negative images (P < .00001). Three months after PDT, near VA declined to 19 letters on positive images and to 26 letters on negative images (P < . 000001). Color vision and contrast sensitivity remained constant during all examinations. Although PDT may not alter the neurosensory retina, it may affect intraretinal function by changing image preference.展开更多
文摘Background: Idiopathic epiretinal membranes (ERM) grow on the surface of the i nternal limiting membrane (ILM) and are a very uncommon condition in young subje cts. Methods: We report six young subjects withERM and describe the spontaneous separation of the membranes. The functional and anatomical recovery was assessed by Snellen visual acuity, Amsler grid and funduscopy. Selected cases were addit ionally assessed by optical coherence tomography (OCT). Results: All subjects in itially claimed a sudden, unilateral, reduction in visual acuity (VA) with sever e distortion at the age of 15-30 years. No ocular trauma or disease was ascerta ined in any case. Initial fundus examination demonstrated a gray-whitish ERM wi th translucent stress lines over the macula. Visual recovery occurred in all cas es after resolution of the ERM. Sequential OCT demonstrated the successive peeli ng of an ERM accompanied by normalization of foveal thickness. Conclusions: Youn g subjects should b e counseled about the favorable prognosis for maintaining go od vision and possible spontaneous membrane separation. Conservative observation is advocated if the visual disturbance is located temporally, as functional rec overy and spontaneous membrane separation may occur. When the contracting forces of the immature ERM are stronger than its adhesions to the retina, the membrane may separate spontaneously.
文摘Purpose: To describe photodynamic therapy (PDT) and additional indocyanine green (ICG) guided feeder vessel pho-tocoagulation as a treatment of choroidal neovascularization (CNV) secondary to choroidal rupture in case of blunt head trauma. Design: Interventional case report. Methods: A 61- year-old woman developed subfoveal CNV originating from a choroid tear 8 years after blunt head trauma. Four sessions of PDT were applied and an additional two consecutive sessions of selective ICG-guided feeder vessel photocoagulation conducted. Results: Transient reduction of leakage and closure of feeder vessels could not prevent further growth of the CNV. Conclusions: PDT reduced leakage temporarily and additional ICG-guided feeder vessel photocoagulation closed treated feeder vessel and CNV. Newfeeder vessel formation and growth of CNV in case of traumatic choroid rupture could not be treated effectively by these two laser treatment modalities to prevent severe deterioration of visual acuity.
文摘To investigate image preferences after photodynamic therapy (PDT). Prospective, cross-sectional study. Seventeen patients with neovascular age-related macular degeneration were tested by color vision, contrast sensitivity, and near visual acuity (VA)-with positive images and negative images before, 1 week after, and 3 months after PDT. Before PDT, 13 patients (76% ) preferred positive images; the difference was not significant (P < .04). One week after PDT, 16 patients (94% ) preferred negative images. The average near VA improved to 27 letters on positive images and to32 letters on negative images (P < .00001). Three months after PDT, near VA declined to 19 letters on positive images and to 26 letters on negative images (P < . 000001). Color vision and contrast sensitivity remained constant during all examinations. Although PDT may not alter the neurosensory retina, it may affect intraretinal function by changing image preference.
