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Genetic analyses of ancient tea trees provide insights into the breeding history and dissemination of Chinese Assam tea(Camellia sinensis var.assamica)
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作者 miao-miao li Muditha K.Meegahakumbura +5 位作者 Moses C.Wambulwa Kevin S.Burgess Michael Möller Zong-Fang Shen De-Zhu li lian-Ming Gao 《Plant Diversity》 SCIE CAS CSCD 2024年第2期229-237,共9页
Chinese Assam tea(Camellia sinensis var.assamica)is an important tea crop with a long history of cultivation in Yunnan,China.Despite its potential value as a genetic resource,its genetic diversity and domestication/br... Chinese Assam tea(Camellia sinensis var.assamica)is an important tea crop with a long history of cultivation in Yunnan,China.Despite its potential value as a genetic resource,its genetic diversity and domestication/breeding history remain unclear.To address this issue,we genotyped 469 ancient tea plant trees representing 26 C.sinensis var.assamica populations,plus two of its wild relatives(six and three populations of C.taliensis and C.crassicolumna,respectively)using 16 nuclear microsatellite loci.Results showed that Chinese Assam tea has a relatively high,but comparatively lower gene diversity(H_(S)=0.638)than the wild relative C.crassicolumna(H_S=0.658).Clustering in STRUCTURE indicated that Chinese Assam tea and its two wild relatives formed distinct genetic groups,with considerable interspecific introgression.The Chinese Assam tea accessions clustered into three gene pools,corresponding well with their geographic distribution.However,New Hybrids analysis indicated that 68.48%of ancient Chinese Assam tea plants from Xishuangbanna were genetic intermediates between the Puer and Lincang gene pools.In addition,10%of the ancient Chinese Assam tea individuals were found to be hybrids between Chinese Assam tea and C.taliensis.Our results suggest that Chinese Assam tea was domesticated separately in three gene pools(Puer,Lincang and Xishuangbanna)in the Mekong River valley and that the hybrids were subsequently selected during the domestication process.Although the domestication history of Chinese Assam tea in southwestern Yunnan remains complex,our results will help to identify valuable genetic resources that may be useful in future tea breeding programs. 展开更多
关键词 Tea plant Hybrid origin Genetic diversity Domestication history Camellia sinensis var.assamica Camellia taliensis
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Distributed hydrological models for addressing effects of spatial variability of roughness on overland flow 被引量:2
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作者 Sheng-tang Zhang Yin liu +1 位作者 miao-miao li Bo liang 《Water Science and Engineering》 EI CAS CSCD 2016年第3期249-255,共7页
In this study, we investigated the origin of the overland flow roughness problem and divided the current overland flow roughness research into three types, as follows: the first type of research takes into account the... In this study, we investigated the origin of the overland flow roughness problem and divided the current overland flow roughness research into three types, as follows: the first type of research takes into account the effects of roughness on the volume and velocity of surface runoff, flood peaks, and the scouring capability of flows, but has not addressed the spatial variability of roughness in detail; the second type of research considers that surface roughness varies spatially with different land usage types, land-cover conditions, and different tillage forms, but lacks a quantitative study of the spatial variability; and the third type of research simply deals with the spatial variability of roughness in each grid cell or land type. We present three shortcomings of the current overland flow roughness research, including(1) the neglect of roughness in distributed hydrological models when simulating the overland flow direction and distribution,(2) the lack of consideration of spatial variability of roughness in hydrological models, and(3) the failure to distinguish the roughness formulas in different overland flow regimes. To solve these problems,distributed hydrological model research should focus on four aspects in regard to overland flow: velocity field observations, flow regime mechanisms, a basic roughness theory, and scale problems. 展开更多
关键词 DISTRIBUTED HYDROLOGICAL model Overland flow ROUGHNESS SPATIAL VARIABILITY
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Effects of surround suppression on response adaptation of V1 neurons to visual stimuli
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作者 Peng li Cai-Hong JIN +5 位作者 San JIANG miao-miao li Zi-Lu WANG Hui ZHU Cui-Yun CHEN Tian-Miao HUA 《Zoological Research》 CAS CSCD 北大核心 2014年第5期411-419,共9页
The influence of intracortical inhibition on the response adaptation of visual cortical neurons remains in debate. To clarify this issue, in the present study the influence of surround suppression evoked through the l... The influence of intracortical inhibition on the response adaptation of visual cortical neurons remains in debate. To clarify this issue, in the present study the influence of surround suppression evoked through the local inhibitory interneurons on the adaptation effects of neurons in the primary visual cortex (V1) were observed. Moreover, the adaptations of V1 neurons to both the high-contrast visual stimuli presented in the classical receptive field (CRF) and to the costimulation presented in the CRF and the surrounding nonclassical receptive field (nCRF) were compared. The intensities of surround suppression were modulated with different sized grating stimuli. The results showed that the response adaptation of V1 neurons decreased significantly with the increase of surround suppression and this adaptation decrease was due to the reduction of the initial response of V1 neurons to visual stimuli. However, the plateau response during adaptation showed no significant changes. These findings indicate that the adaptation effects of V1 neurons may not be directly affected by surround suppression, but may be dynamically regulated by a negative feedback network and be finely adjusted by its initial spiking response to stimulus. This adaptive regulation is not only energy efficient for the central nervous system, but also beneficially acts to maintain the homeostasis of neuronal response to long-presenting visual signals. 展开更多
关键词 Surround suppression V1 neurons Response adaptation CAT
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放疗联合高强度聚焦超声治疗胰腺癌的研究 被引量:8
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作者 施琦 马士杰 +3 位作者 周传文 谢睿 李苗苗 沈鹏 《中国现代医学杂志》 CAS 2020年第7期59-63,共5页
目的探讨放疗联合高强度聚焦超声治疗胰腺癌的疗效。方法将南京医科大学附属淮安第一医院收治的100例中晚期胰腺癌患者随机分为观察组及对照组,每组50例。对照组采用放疗,观察组在对照组的基础上联合高强度聚焦超声治疗;治疗前后检测患... 目的探讨放疗联合高强度聚焦超声治疗胰腺癌的疗效。方法将南京医科大学附属淮安第一医院收治的100例中晚期胰腺癌患者随机分为观察组及对照组,每组50例。对照组采用放疗,观察组在对照组的基础上联合高强度聚焦超声治疗;治疗前后检测患者血清学指标、影像学指标,观察临床症状及不良反应。结果治疗后两组患者血清糖类抗原199(CA199)、糖类抗原242(CA242)、骨桥蛋白(OPN)、中性粒细胞明胶酶相关运载蛋白(NGAL)及视黄醇结合蛋白4(RBP4)水平比较,差异有统计学意义(P<0.05),观察组低于对照组。两组患者血清谷丙转氨酶(ALT)、天门冬氨酸氨基转移酶(AST)、血尿素氮(BUN)及肌酐(Cr)水平比较,差异有统计学意义(P<0.05),观察组低于对照组。两组治疗前后血清中DJ-1及microRNA-155(miR-155)比较,差异有统计学意义(P<0.05)。治疗后两组患者血清DJ-1及miR-155水平均有所降低,且治疗后观察组低于对照组。观察组患者回声均有不同程度增强,其中5例肿瘤组织内出现小的无回声区。对照组患者回声未出现明显增强。观察组患者疼痛完全缓解率为89%(41/46),对照组患者疼痛程度无明显缓解。观察组患者食欲均出现不同程度的改善,体重均出现不同程度的增加,对照组患者饮食及体重无明显改变。治疗后,观察组平均体重重于对照组(P<0.05)。结论采用调强放疗联合高强度聚焦超声治疗胰腺癌后可有效提高临床疗效,并降低患者血清DJ-1及miR-155水平。 展开更多
关键词 胰腺肿瘤 螺旋断层调强放疗 高强度聚焦超声 DJ-1 microRNA-155
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关节镜下同种异体肌腱重建喙锁韧带与锁骨钩钢板固定治疗肩锁关节脱位的疗效对比 被引量:9
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作者 徐文松 薛辉 +3 位作者 李苗苗 马微 崔阳 王文娟 《中国内镜杂志》 2021年第9期31-36,共6页
目的比较关节镜下同种异体肌腱重建喙锁韧带与锁骨钩钢板固定治疗肩锁关节脱位的临床疗效。方法选取110例完全性肩锁关节脱位的患者随机分成两组,治疗组(n=55)采用关节镜下同种异体肌腱重建喙锁韧带治疗,对照组(n=55)采用锁骨钩钢板固... 目的比较关节镜下同种异体肌腱重建喙锁韧带与锁骨钩钢板固定治疗肩锁关节脱位的临床疗效。方法选取110例完全性肩锁关节脱位的患者随机分成两组,治疗组(n=55)采用关节镜下同种异体肌腱重建喙锁韧带治疗,对照组(n=55)采用锁骨钩钢板固定。比较两组患者的疗效、手术指标及喙锁间距。结果治疗组美国肩肘外科医师协会评分(ASES)和优良率明显高于对照组,固定对照组钢板取出后肩关节功能明显优于钢板取出前(P <0.05)。治疗组休息、活动时疼痛明显轻于对照组(P <0.05)。对照组疼痛主要集中在活动时,在钢板取出后疼痛明显减轻。治疗组手术时间、平均住院时间和末次随访时喙锁间距明显较对照组短,手术出血量明显较对照组少(均P <0.05)。两组患者并发症比较,差异无统计学意义(P> 0.05)。结论与锁骨钩钢板固定相比,关节镜下同种异体肌腱重建喙锁韧带治疗肩锁关节脱位具有创伤小、疼痛轻和功能恢复快的优势。 展开更多
关键词 肩锁关节脱位 同种异体肌腱 喙锁韧带重建 锁骨钩钢板固定术 关节镜技术
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Enantioselective trapping of palladium-stabilized oxo-1,4-dipoles with photochemically generated ketenes 被引量:1
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作者 miao-miao li Bao-Le Qu +2 位作者 Yu-Qing Xiao Wen-Jing Xiao liang-Qiu Lu 《Science Bulletin》 SCIE EI CSCD 2021年第17期1719-1722,M0003,共5页
The development of efficient strategies for constructing oxo-heterocyclic architectures is a highly significant topic in modern synthetic chemistry,due to their wide existence in plenty of natural products,medical and... The development of efficient strategies for constructing oxo-heterocyclic architectures is a highly significant topic in modern synthetic chemistry,due to their wide existence in plenty of natural products,medical and agricultural chemicals[1-4].It is well-known that selectivity,especially stereoselectivity,still lags largely behind many precedent endeavors,which stimulates the synthetic community to search for more efficient and selective methods for oxo-heterocycle synthesis. 展开更多
关键词 氧杂环化合物 环加成反应 立体选择性 合成化学 对映选择性 钯催化 选择性控制 药物分子
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基于聚硼硅氧烷的自愈合光子晶体弹性体 被引量:5
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作者 李苗苗 吕全乾 +1 位作者 朱锦涛 张连斌 《高分子学报》 SCIE CAS CSCD 北大核心 2019年第3期271-280,M0005,共11页
通过硼酸(BA)交联羟基封端的聚二甲基硅氧烷(Hydroxyl-PDMS)得到聚硼硅氧烷(PBS)弹性体,并与单分散的SiO2纳米粒子(SiO2 NPs)和炭黑纳米粒子(CB NPs)共组装,进而得到无角度依赖的光子晶体弹性体.通过光纤光谱仪表征了不同结构色光子晶... 通过硼酸(BA)交联羟基封端的聚二甲基硅氧烷(Hydroxyl-PDMS)得到聚硼硅氧烷(PBS)弹性体,并与单分散的SiO2纳米粒子(SiO2 NPs)和炭黑纳米粒子(CB NPs)共组装,进而得到无角度依赖的光子晶体弹性体.通过光纤光谱仪表征了不同结构色光子晶体弹性体的光学性质,利用光学显微镜和应力-应变测试分别对光子晶体弹性体表面划痕和裂痕的自愈合性能进行了系统表征.结果表明,该光子晶体弹性体材料的结构色不随观测角度的改变而发生变化,即具有无角度依赖的结构色.同时,该光子晶体弹性体在形变过程中可实现颜色改变;更为重要的是,光子晶体弹性体的链柔性及动态可逆键使其在室温条件下即可展现出自愈合性能,可实现表面划痕及裂痕的快速愈合.此外,通过喷涂法可简单快速地制备具有明亮结构色的大面积光子晶体膜材料,拓展了该光子晶体材料在彩色涂层、显示板、印刷等领域的应用. 展开更多
关键词 光子晶体 无角度依赖结构色 自愈合 弹性体 聚硼硅氧烷
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Taxonomic revision of the genus Phryganogryllacris (Orthoptera: Gryllacrididae) from China
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作者 miao-miao li Yan Fang +1 位作者 Xian-Wei liu Kai li 《Zoological Systematics》 CSCD 北大核心 2014年第4期507-519,共13页
A taxonomic revision of the genus Phryganogryllacris Karny, 1937 is provided. Twelve species of the genus from China are recorded, including 5 species described as new to science, namely P. sichuanensis Li, Liu & Li,... A taxonomic revision of the genus Phryganogryllacris Karny, 1937 is provided. Twelve species of the genus from China are recorded, including 5 species described as new to science, namely P. sichuanensis Li, Liu & Li, sp. nov., P. parva Li, Liu & Li, sp. nov., P. truncata Li, Liu & Li, sp. nov., P. interrupta Li, Liu & Li, sp. nov. and P. longicerca Li, Liu & Li, sp. nov. Two new combinations are also reported here, P. gialai(Gorochov, 2004)(Vietnam) comb. nov. and P. alia(Gorochov, 2004)(Vietnam) comb. nov. A key to Chinese species of the genus was provided. 展开更多
关键词 Gryllacridinae Phryganogryllacris new species new combination China
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