A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C1...A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C18 column （50 mm × 4.6 mm i.d., 1.9 μm particle size） with a gradient mobile phase of acetonitrile-ammonium acetate-tetrabutylammoniumhydrogen sulfate buffer, at a flow rate of 1,8 mL/min and UV detection at 230 nm. Naturally aged samples were also tested to determine sample stability. A profile of sample and impurity breakdown was also presented.展开更多
The editorial group is pleased to release this special issue of Family Medicine and Community Health-a Sino-Australian forum.We are grateful to the contributing authors from China and Australia.The contents of this is...The editorial group is pleased to release this special issue of Family Medicine and Community Health-a Sino-Australian forum.We are grateful to the contributing authors from China and Australia.The contents of this issue cover a wide range of topics ranging from infant care to aged care,from disease management to socio-behavioural interventions.展开更多
文摘A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C18 column （50 mm × 4.6 mm i.d., 1.9 μm particle size） with a gradient mobile phase of acetonitrile-ammonium acetate-tetrabutylammoniumhydrogen sulfate buffer, at a flow rate of 1,8 mL/min and UV detection at 230 nm. Naturally aged samples were also tested to determine sample stability. A profile of sample and impurity breakdown was also presented.
文摘The editorial group is pleased to release this special issue of Family Medicine and Community Health-a Sino-Australian forum.We are grateful to the contributing authors from China and Australia.The contents of this issue cover a wide range of topics ranging from infant care to aged care,from disease management to socio-behavioural interventions.
