Peptide amphiphiles with well-organized secondary structure are an important family of molecules that are known to assemble into a variety of nanostructures.In this work,we present three guanidiniocarbonylpyrrole(GCP)...Peptide amphiphiles with well-organized secondary structure are an important family of molecules that are known to assemble into a variety of nanostructures.In this work,we present three guanidiniocarbonylpyrrole(GCP)containing peptide amphiphiles,which show versatile morphology and secondary structure changes as a result of different chain lengths and in different concentration regimes.The random coil conformation,α-helix,andβ-sheet are obtained for peptide 1,peptide 2,and peptide 3,respectively under neutral aqueous conditions.Furthermore,all peptide amphiphiles can aggregate to form nanoparticles at low concentrations.However,at high concentrations,peptide 1 selfassembles into left-ha nded twisted helical fibers,while longer bamboo-like mo rphology can be obse rved exclusively for peptide 2.For peptide 3,freshly prepared samples show uniform spherical morphology,whereas an obvious morphological transition from original nanoparticles to disordered fibers was realized after incubating for one week.These fascinating morphology changes were determined by the combination of circular dichroism,dynamic light scattering,transmission electron microscopy,atomic force microscopy,and theoretical calculations.展开更多
Within the past two decades,chromophores,which show aggregation-induced emission(AIE),have gained considerable attention with respect to the development of luminescent liquid crystals.In contrast to common luminogens,...Within the past two decades,chromophores,which show aggregation-induced emission(AIE),have gained considerable attention with respect to the development of luminescent liquid crystals.In contrast to common luminogens,AIE emitters do not suffer from aggregation-caused quenching of the emission in the solid state.In this review,we summarize the recent development in the field of AIE-active liquid crystals and show first model devices,which already prove the application potential of these materials.Currently,three different approaches are followed,to get access to luminescent liquid crystals––namely the synthetic approach yielding luminescent mesogens,the doping approach,and the supramolecular approach,which will be described and discussed in detail in this review.展开更多
基金supported by the National Natural Science Foundation of China(No.21572101)the Natural Science Foundation of Jiangsu Province(No.BK20180055)+1 种基金Qinghai Provincial Key Laboratory of Tibetan Medicine Research(No.2017-ZJ-Y11)funding by the Fonds der Chemischen Industrie(Liebig-Fellowship)。
文摘Peptide amphiphiles with well-organized secondary structure are an important family of molecules that are known to assemble into a variety of nanostructures.In this work,we present three guanidiniocarbonylpyrrole(GCP)containing peptide amphiphiles,which show versatile morphology and secondary structure changes as a result of different chain lengths and in different concentration regimes.The random coil conformation,α-helix,andβ-sheet are obtained for peptide 1,peptide 2,and peptide 3,respectively under neutral aqueous conditions.Furthermore,all peptide amphiphiles can aggregate to form nanoparticles at low concentrations.However,at high concentrations,peptide 1 selfassembles into left-ha nded twisted helical fibers,while longer bamboo-like mo rphology can be obse rved exclusively for peptide 2.For peptide 3,freshly prepared samples show uniform spherical morphology,whereas an obvious morphological transition from original nanoparticles to disordered fibers was realized after incubating for one week.These fascinating morphology changes were determined by the combination of circular dichroism,dynamic light scattering,transmission electron microscopy,atomic force microscopy,and theoretical calculations.
基金Prof.Werdelmann StiftungBoehringer Ingelheim Stiftung+1 种基金Center for Nanointegration Duisburg-EssenFonds der chemischen Industrie。
文摘Within the past two decades,chromophores,which show aggregation-induced emission(AIE),have gained considerable attention with respect to the development of luminescent liquid crystals.In contrast to common luminogens,AIE emitters do not suffer from aggregation-caused quenching of the emission in the solid state.In this review,we summarize the recent development in the field of AIE-active liquid crystals and show first model devices,which already prove the application potential of these materials.Currently,three different approaches are followed,to get access to luminescent liquid crystals––namely the synthetic approach yielding luminescent mesogens,the doping approach,and the supramolecular approach,which will be described and discussed in detail in this review.