Colorectal cancer(CRC)is the second most deadly adult cancer in men and women combined,accountable 9.2%of all cancer deaths.^(1)Drug resistance to chemotherapies,such as 5-FU-related regimens,remains a major cause of ...Colorectal cancer(CRC)is the second most deadly adult cancer in men and women combined,accountable 9.2%of all cancer deaths.^(1)Drug resistance to chemotherapies,such as 5-FU-related regimens,remains a major cause of cancer recurrence and death in patients with CRC.Aberrant metabolic changes in cancer cells are a significant cancer hallmark.展开更多
基金supported by The Wells Center for Pediatric Research,Riley Children’s Foundation,Jeff Gordon Children’s Foundation,and IU Simon Cancer Center.
文摘Colorectal cancer(CRC)is the second most deadly adult cancer in men and women combined,accountable 9.2%of all cancer deaths.^(1)Drug resistance to chemotherapies,such as 5-FU-related regimens,remains a major cause of cancer recurrence and death in patients with CRC.Aberrant metabolic changes in cancer cells are a significant cancer hallmark.
