BACKGROUND The clinical presentation of acute lymphoblastic lymphoma is highly varied.While prognosis is good, recurrence of disease can occur. Gastrointestinal relapse, including intussusception, is well-described bu...BACKGROUND The clinical presentation of acute lymphoblastic lymphoma is highly varied.While prognosis is good, recurrence of disease can occur. Gastrointestinal relapse, including intussusception, is well-described but the absence of abdominal pain in this setting is rare.CASE SUMMARY We report a 13-year-old male with B-cell precursor acute lymphoblastic leukemia in remission presenting with anemia and weight loss. Examination was significant for absence of abdominal pain, but a stool sample was positive for occult blood. Pan-endoscopy was performed with colonoscopy revealing a mass filling the colonic lumen. Biopsy of the mass confirmed recurrence of recurrent Bcell lymphoma. Computed tomography scan revealed ileocolic intussusception resulting from the tumor. This case is unusual in that the patient had no abdominal pain despite the presence of intussusception.CONCLUSION While intestinal involvement with lymphoma has been well described in the literature, presentation as painless intussusception has not been reported. This case report highlights the wide spectrum of clinical manifestations of recurrent Bcell lymphoma involving the gastrointestinal tract, in particular the near absence of symptoms despite the finding of intussusception.展开更多
Background: Eosinophilic esophagitis (EoE) is thought to be more common in males and Caucasians, yet little data exists regarding the presentation of EoE among children. Methods: A retrospective study of children unde...Background: Eosinophilic esophagitis (EoE) is thought to be more common in males and Caucasians, yet little data exists regarding the presentation of EoE among children. Methods: A retrospective study of children undergoing esophagogastroduodenoscopy (EGD) was done to determine gender and racial differences in the prevalence and presenting symptoms of EoE. Data collected included gender, race, indication for EGD, and presence of EoE. Results: No gender or racial differences were found for indication for EGD. EoE was identified in 4.1% of children, more commonly in males than females (6% vs. 2.5%,展开更多
文摘BACKGROUND The clinical presentation of acute lymphoblastic lymphoma is highly varied.While prognosis is good, recurrence of disease can occur. Gastrointestinal relapse, including intussusception, is well-described but the absence of abdominal pain in this setting is rare.CASE SUMMARY We report a 13-year-old male with B-cell precursor acute lymphoblastic leukemia in remission presenting with anemia and weight loss. Examination was significant for absence of abdominal pain, but a stool sample was positive for occult blood. Pan-endoscopy was performed with colonoscopy revealing a mass filling the colonic lumen. Biopsy of the mass confirmed recurrence of recurrent Bcell lymphoma. Computed tomography scan revealed ileocolic intussusception resulting from the tumor. This case is unusual in that the patient had no abdominal pain despite the presence of intussusception.CONCLUSION While intestinal involvement with lymphoma has been well described in the literature, presentation as painless intussusception has not been reported. This case report highlights the wide spectrum of clinical manifestations of recurrent Bcell lymphoma involving the gastrointestinal tract, in particular the near absence of symptoms despite the finding of intussusception.
文摘Background: Eosinophilic esophagitis (EoE) is thought to be more common in males and Caucasians, yet little data exists regarding the presentation of EoE among children. Methods: A retrospective study of children undergoing esophagogastroduodenoscopy (EGD) was done to determine gender and racial differences in the prevalence and presenting symptoms of EoE. Data collected included gender, race, indication for EGD, and presence of EoE. Results: No gender or racial differences were found for indication for EGD. EoE was identified in 4.1% of children, more commonly in males than females (6% vs. 2.5%,