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A Validated Model for the Imaging Diagnosis of Cystic Lung Disease
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作者 Wallace T. Miller Karen C. Patterson +22 位作者 Shweta Sood James E. Schmitt Arshad A. Wani Robert Borden Maya Galperin-Aisenberg Mary K. Porteus Michelle L. Hershman michael Hewitt Jennifer Levy Victor D. Babatunde Tetiana Glushko Timothy J. Niesen Sergey Leshchinskiy Karine Sahakyan Keyur Desai Jennifer A. Gillman Sandeep Reddy michael shriver Nathaniel B. Linna Abass M. Noor Aysenur Buz Matthew E. Biron Scott Simpson 《Open Journal of Radiology》 2023年第1期42-57,共16页
Rationale and Objectives: Cystic lung disease may be accurately diagnosed by imaging interpretation of specialist radiologists, without other information. We hypothesized that with minimal training non-specialists cou... Rationale and Objectives: Cystic lung disease may be accurately diagnosed by imaging interpretation of specialist radiologists, without other information. We hypothesized that with minimal training non-specialists could perform similarly to specialist physicians in the diagnosis of cystic lung disease. Methods: 72 cystic lung disease cases and 25 cystic lung disease mimics were obtained from three sources: 1) a prospective acquired diffuse lung disease registry, 2) a retrospective search of medical records and 3) teaching files. Cases were anonymized, randomized and interpreted by 7 diffuse lung disease specialists and 15 non-specialist radiologists and pulmonologists. Clinical information other than age and sex was not provided. Prior to interpretation, non-specialists viewed a short PDF training document explaining cystic lung disease interpretation. Results: Correct first choice diagnosis of 85%-88% may be achieved by high-performing specialist readers and 71%-80% by non-specialists and lower-performing specialists, with mean accuracies in the diagnosis of LAM (91%, p Conclusion: With specific but limited training, non-specialist physicians can diagnose cystic lung diseases from CT appearance alone with similar accuracy to specialists, correctly identifying approximately 75% of cases. 展开更多
关键词 LYMPHANGIOLEIOMYOMATOSIS HISTIOCYTOSIS Langerhans-Cell Idiopathic Interstitial Pneumonias Birt-Hogg-Dube Syndrome Lung Diseases INTERSTITIAL DIAGNOSES Differential
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立体定向脑电图相关并发症的系统评价
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作者 Jeffrey P Mullin michael shriver +2 位作者 Soha Alomar 肖英凤 慕洁 《癫痫杂志》 2017年第4期354-363,共10页
立体定向脑电图(SEEG)是针对难治性癫痫患者的一项术前评估手段,可定位致痫灶及可能相关的功能皮质区的解剖位置。避免大骨瓣开颅术及其植入精确性,SEEG可能减少相关并发症。然而,由于植入并发症相对较高,颅内电极被认为是具有过度侵入... 立体定向脑电图(SEEG)是针对难治性癫痫患者的一项术前评估手段,可定位致痫灶及可能相关的功能皮质区的解剖位置。避免大骨瓣开颅术及其植入精确性,SEEG可能减少相关并发症。然而,由于植入并发症相对较高,颅内电极被认为是具有过度侵入性的操作。此前并无关于SEEG并发症的系统文献综述及Meta分析。该研究的目的是定量回顾文献中SEEG电极植入后各种手术并发症的发生率并进行汇总评估,以便内科医生能够就该术外侵入性监测的相关潜在并发症提供准确建议。此项系统评价是基于PRISMA实现的。通过检索MEDLINE,Scopus,Web of Science数据库,用逆方差加权的固定效应模型对并发症的发生率进行分析。Meta分析与森林图的制作都是通过成熟的制表软件完成的。主要结局指标是总效应量及其95%置信区间(CI)。检索到的1 901篇文献,除重787篇后,通过标题和摘要对1 114篇文章进行了筛选。在这一阶段,排除了没有提及SEEG术后并发症或未达到纳入标准的研究。在排除1 057篇文献后,对剩余的57篇文献进行全文阅读以确定合格标准。最常见的并发症是出血[合并患病率1.0%,95%CI(0.6,1.4)]或感染[合并患病率0.8%,95%CI(0.3,1.2)]。确定了5例死亡[合并患病率0.3%,95%CI(0.1,0.6)]。文章分析确定了与SEEG植入和监测相关的121例手术并发症[合并患病率1.3%,95%CI(0.9,1.7)]。对SEEG相关并发症的实际发生率的综合评估。相比其他术外侵入性监测方法,SEEG并发症的发生率实际上更低。这些数据可能减轻一些关于"立体定位"方法的安全性的担忧,在选择不同的侵入性监测方法时做出更好的决策,并减轻深度电极植入相关的恐惧。 展开更多
关键词 癫痫手术 立体定向脑电图 立体定位 安全性
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