Food crops(bush mango(n=12),roasted cashew nut(n=12),dried okra(n=12),sesame(n=35)and sorghum(n=36))sold in markets in Nasarawa state,Nigeria,were analyzed using a LC-MS/MS mycotoxin method.The hepatocarcinogenic afla...Food crops(bush mango(n=12),roasted cashew nut(n=12),dried okra(n=12),sesame(n=35)and sorghum(n=36))sold in markets in Nasarawa state,Nigeria,were analyzed using a LC-MS/MS mycotoxin method.The hepatocarcinogenic aflatoxin B_(1) was detected in 42%,25%and 19%of bush mango,dried okra and sorghum samples at mean concentrations of 19.2μg/kg,8.27μg/kg and 4.75μg/kg,respectively,while fumonisin B_(1) contaminated 9%of the sesame(mean:12.5μg/kg)and 47%of the sorghum(mean:461μg/kg)samples.At least 19%of the sorghum samples were co-contaminated with aflatoxin B_(1) and fumonisin B_(1).The nephrotoxic ochratoxin A was detected in bush mango,sorghum and,for the first time to the best of our knowledge,in dried okra.These vended food crops in the local markets are therefore prone to mycotoxin contamination,which may pose a health threat to consumers,and require intentional mitigation efforts.展开更多
The short-and long-term stability of multi-component mixtures and intermediate mixtures of analytical standards of veterinary drugs,which can potentially occur in food and feed chains,was examined by an isochronous me...The short-and long-term stability of multi-component mixtures and intermediate mixtures of analytical standards of veterinary drugs,which can potentially occur in food and feed chains,was examined by an isochronous measurement approach.Short-term stability testing of calibrants included storage for 1,2,4,and 7 days at-20℃(as a baseline)4℃,and 23℃(with and without exposure to sunlight),respectively.Long-term stability testing conditions of intermediate mixes were-20℃,4℃,23℃(with and without exposure to sunlight),and control temperature at-80℃while the testing period was 2,4,8,and 12 weeks,respectively.Results indicated that calibration standards should ideally be stored at 4℃for only 1~2 days,without the presence of acid.Neutral storage conditions were acceptable even at room temperature.Storage of intermediate mixtures containingß-lactams and cephalosporins for longer than 1 month under 4℃ and room temperature resulted in a loss of almost 90%.When it comes to the intermediate mixtures with penicillin V and G,acceptable storage conditions were 2 weeks at-20℃,without the presence of acid.Other classes of veterinary drugs were less critical as considers long-term stability.Overall,storage conditions at-20℃were considered optimal for long-term storage of intermediate mixes of veterinary drug standards.展开更多
文摘Food crops(bush mango(n=12),roasted cashew nut(n=12),dried okra(n=12),sesame(n=35)and sorghum(n=36))sold in markets in Nasarawa state,Nigeria,were analyzed using a LC-MS/MS mycotoxin method.The hepatocarcinogenic aflatoxin B_(1) was detected in 42%,25%and 19%of bush mango,dried okra and sorghum samples at mean concentrations of 19.2μg/kg,8.27μg/kg and 4.75μg/kg,respectively,while fumonisin B_(1) contaminated 9%of the sesame(mean:12.5μg/kg)and 47%of the sorghum(mean:461μg/kg)samples.At least 19%of the sorghum samples were co-contaminated with aflatoxin B_(1) and fumonisin B_(1).The nephrotoxic ochratoxin A was detected in bush mango,sorghum and,for the first time to the best of our knowledge,in dried okra.These vended food crops in the local markets are therefore prone to mycotoxin contamination,which may pose a health threat to consumers,and require intentional mitigation efforts.
文摘The short-and long-term stability of multi-component mixtures and intermediate mixtures of analytical standards of veterinary drugs,which can potentially occur in food and feed chains,was examined by an isochronous measurement approach.Short-term stability testing of calibrants included storage for 1,2,4,and 7 days at-20℃(as a baseline)4℃,and 23℃(with and without exposure to sunlight),respectively.Long-term stability testing conditions of intermediate mixes were-20℃,4℃,23℃(with and without exposure to sunlight),and control temperature at-80℃while the testing period was 2,4,8,and 12 weeks,respectively.Results indicated that calibration standards should ideally be stored at 4℃for only 1~2 days,without the presence of acid.Neutral storage conditions were acceptable even at room temperature.Storage of intermediate mixtures containingß-lactams and cephalosporins for longer than 1 month under 4℃ and room temperature resulted in a loss of almost 90%.When it comes to the intermediate mixtures with penicillin V and G,acceptable storage conditions were 2 weeks at-20℃,without the presence of acid.Other classes of veterinary drugs were less critical as considers long-term stability.Overall,storage conditions at-20℃were considered optimal for long-term storage of intermediate mixes of veterinary drug standards.
