Conformation analysis of the model compounds for tunicamycin V and its natural donor substrate, UDP-N-acetylglucose, is performed to reveal the detail of the inhibition process.
The conformation analysis of the donor substrate guanosine-5- diphospho-fucose(GDP-fucose,)via 0 model compound to mimic the complex of GDP-fucose with divalent cation is performed by means of molecular dynamics.energ...The conformation analysis of the donor substrate guanosine-5- diphospho-fucose(GDP-fucose,)via 0 model compound to mimic the complex of GDP-fucose with divalent cation is performed by means of molecular dynamics.energy minimization and grid scan technique .展开更多
文摘Conformation analysis of the model compounds for tunicamycin V and its natural donor substrate, UDP-N-acetylglucose, is performed to reveal the detail of the inhibition process.
文摘The conformation analysis of the donor substrate guanosine-5- diphospho-fucose(GDP-fucose,)via 0 model compound to mimic the complex of GDP-fucose with divalent cation is performed by means of molecular dynamics.energy minimization and grid scan technique .