A novel multicomponent high-Cr CoNi-based superalloy with superior comprehensive performance was prepared,and the evaluation of its high-temperature microstructural stability,oxidation resistance,and mechanical proper...A novel multicomponent high-Cr CoNi-based superalloy with superior comprehensive performance was prepared,and the evaluation of its high-temperature microstructural stability,oxidation resistance,and mechanical properties was conducted mainly using its cast polycrystalline alloy.The results disclosed that the morphology of theγ′phase remained stable,and the coarsening rate was slow during the long-term aging at 900–1000℃.The activation energy forγ′precipitate coarsening of alloy 9CoNi-Cr was(402±51)kJ/mol,which is higher compared with those of CMSX-4 and some other Ni-based and Co-based superalloys.Importantly,there was no indica-tion of the formation of topologically close-packed phases during this process.All these factors demonstrated the superior microstructural stability of the alloy.The mass gain of alloy 9CoNi-Cr was 0.6 mg/cm^(2) after oxidation at 1000℃ for 100 h,and the oxidation resistance was comparable to advanced Ni-based superalloys CMSX-4,which can be attributed to the formation of a continuous Al_(2)O_(3) protective layer.Moreover,the compressive yield strength of this cast polycrystalline alloy at high temperatures is clearly higher than that of the conventional Ni-based cast superalloy and the compressive minimum creep rate at 950℃ is comparable to that of the conventional Ni-based cast superalloy,demonstrating the alloy’s good mechanical properties at high temperature.This is partially because high Cr is bene-ficial in improving theγandγ′phase strengths of alloy 9CoNi-Cr.展开更多
Shallow Hilbert curve patterns with easily programmable texture density were selected for laser texturing of stainless steel substrates.Two different texture path segment lengths(12 and 24 μm)and four different laser...Shallow Hilbert curve patterns with easily programmable texture density were selected for laser texturing of stainless steel substrates.Two different texture path segment lengths(12 and 24 μm)and four different laser power percentages(5%,10%,15%,and 20%)were investigated.The textured and smooth substrates were coated with thin polydopamine/polytetrafluoroethylene(PDA/PTFE)coatings for tribological property assessment.The effects of texture density(texture area coverage)and laser power on the durability and friction of the coated surfaces were studied.Laser texturing the substrates improved the coating durability up to 25 times,reduced the friction coefficient,and prevented coating global delamination.The textures fabricated with a laser power of 15%and a texture path segment length of 12 μm yielded the best coating durability.The textures provided the interlocking for the PTFE coating and thus prevented its global delamination.Furthermore,the PTFE inside the texture grooves replenished the solid lubricant worn away in the wear track and prolonged the coating wear life.展开更多
Hemodialysis is the main alternative therapy for patients with end-stage renal disease;most of the hemodialysis centers in China are not designed together with the inpatient ward.During the hospitalization period,hemo...Hemodialysis is the main alternative therapy for patients with end-stage renal disease;most of the hemodialysis centers in China are not designed together with the inpatient ward.During the hospitalization period,hemodialysis patients often move back and forth between wards and hemodialysis rooms because of the treatment needed.Hemodialysis patients are a special group of hospitalized patients,most of them are elderly patients.The overall basic diseases of the patients vary very much,and the cause of the disease is complex.Moreover,the chronic inflammation progresses slowly,and immune function declines.Some of the patient are seriously ill or even hav organ failure.All these factors affect the patients in general.Therefore,the transfer safety of patients during hospitalization is facing great challenges.The researchers reviewed the status of transshipment research in Chinese hemodialysis patients and laid the foundation for the research and development of related handover tools and perfect handover mode in the future.展开更多
Considering that pressure-induced formation of short,strong covalent bonds in light-element compounds can produce superhard materials,we employ structure searching and first-principles calculations to predict a new cl...Considering that pressure-induced formation of short,strong covalent bonds in light-element compounds can produce superhard materials,we employ structure searching and first-principles calculations to predict a new class of boron nitrides with a stoichiometry of BN_(2),which are stable relative to alpha-B and alpha-N_(2) at ambient pressure.At ambient pressure,the most stable phase has a layered structure(h-BN_(2)) containing hexagonal BN layers between which there are intercalated N_(2) molecules.At 25 GPa,a three-dimensional P4_(2)/mmc structure with single N-N bonds becomes the most stable.Dynamical,thermal,and mechanical stability calculations reveal that this structure can be recovered under ambient conditions.Its calculated stress-strain relations demonstrate an intrinsic superhard nature with an estimated Vickers hardness of ~43 GPa.This structure has a potentially high energy density of ~4.19 kJ/g.展开更多
[Objectives]The paper was to investigate the clinical effect of Fuyang prescription in the treatment of yang deficiency syndrome in the convalescent stage of ischemic stroke(IS)and its mechanism of action.[Methods]A t...[Objectives]The paper was to investigate the clinical effect of Fuyang prescription in the treatment of yang deficiency syndrome in the convalescent stage of ischemic stroke(IS)and its mechanism of action.[Methods]A total of 50 patients with yang deficiency syndrome in the convalescent stage of IS were randomly divided into treatment group and control group,with 25 patients in each group.The patients in the treatment group were given basic treatment combined with Fuyang prescription,and those in the control group were given basic treatment combined with Buyang Huanwu decoction;the course of treatment was 28 d for both groups.The activities of daily living(ADL)score,National Institutes of Health Stroke Scale(NIHSS)score,quality of life score,TCM syndrome score,and safety in both groups were observed before treatment and at 14 and 28 d post treatment,and their clinical outcome was evaluated.[Results]There was a significant difference in overall response rate between the treatment group and the control group[92.00%(23/25)vs 76.00%(19/25),P<0.05].After treatment,both groups had significant changes in ADL score,NIHSS score,quality of life score,and TCM syndrome score,and there were significant differences in these indices between the two groups at the same time point after treatment(P<0.05 or P<0.01).There were no significant changes in routine blood,routine stool,routine urine,and liver/renal function in either group after treatment.[Conclusions]Fuyang prescription has a marked clinical effect in the treatment of yang deficiency syndrome in the convalescent stage of IS,with significantly better clinical effect than Buyang Huanwu decoction,and it provides clinical evidence for the traditional Chinese medicine theory of yang supporting in the treatment of IS in the convalescent stage.展开更多
The industrial application of nano-photocatalysts in wastewater treatment has been severely restricted for a long time due to their difficult separation,poor reusability,and low efficiency.In this work,a facile strate...The industrial application of nano-photocatalysts in wastewater treatment has been severely restricted for a long time due to their difficult separation,poor reusability,and low efficiency.In this work,a facile strategy was proposed to enhance the photocatalytic activity and recovery performance of Ag@AgCl nanocatalysts.Biological veins(Bio-veins)with a unique 3D porous construction were used as carriers for the in-situ growth of Ag@AgCl nanoparticles.Scanning electron microscopy results showed that the Ag@AgCl nanoparticles were uniformly loaded on the surface and interior of the Bio-veins,and the size of the Ag@AgCl nanoparticles immobilized on the Bio-veins(50–300 nm)was significantly smaller than Ag@AgCl obtained by the co-precipitation method(1–3μm).The Bio-veins played a vital role in the photocatalysis reaction system.The degradation efficiency of the Ag@AgCl/Bio-veins(CI4)was up to 3.50 times as high as pure Ag@AgCl.Furthermore,the composites also exhibited excellent recyclability and stability under both visible and solar light.This work provided a suitable strategy for nano-photocatalysts for practical application and may also offer new possibilities for the high-value utilization of biomass materials.展开更多
A novel way of producing superhydrophobic surfaces by applying a self-assembled monolayer(SAM)to silicon micro/nano-textured surfaces is presented in this paper.The micro/nano-textured surfaces on silicon substrates w...A novel way of producing superhydrophobic surfaces by applying a self-assembled monolayer(SAM)to silicon micro/nano-textured surfaces is presented in this paper.The micro/nano-textured surfaces on silicon substrates were generated by the aluminum-induced crystallization(AIC)of amorphous silicon(a-Si)technique.Octadecyltrichlorosilane(OTS)SAMs were then applied to the textured surfaces by dip coating.The topography and wetting properties of the resulting surfaces were characterized using scanning electron microscopy(SEM)and a video-based contact angle measurement system.The results show that by introducing OTS SAMs on the silicon micro/nano-textured surfaces,superhydrophobic surfaces with water contact angles(WCAs)of 155°were obtained,as compared to the WCAs of OTS-modified smooth silicon surfaces of about 112°.Surface topography was found to directly influence the WCA as predicted by the Cassie-Baxter model.展开更多
Herein, a multiwalled carbon nanotubes(MWNT)-based colorimetric probe was designed to discover and monitor the level of apolipoprotein-L1(Apo L1) in lumbar disc herniation(LDH) patients. Apo L1 could be easily found i...Herein, a multiwalled carbon nanotubes(MWNT)-based colorimetric probe was designed to discover and monitor the level of apolipoprotein-L1(Apo L1) in lumbar disc herniation(LDH) patients. Apo L1 could be easily found in human serum of the LDH group, but not obviously expressed in the normal control group(Ctrl), spine spondylolisthesis(SSP) group, spinal fracture(SFR) group, and spine scoliosis(SSC) group. Furthermore, the as-prepared MWNT-based probe was also used to track the recovery of LDH patients who have successful surgery operation. The P value of early diagnosis and recovery monitoring was <0.001 and >0.05 for the proposed method and a conventional enzyme-linked immunosorbent assay(ELISA), respectively, suggesting this detection strategy had significant differences compared with the traditional ELISA. All experimental results showed that Apo L1 might be a potential biomarker for early diagnosis of LDH. This proposed detection strategy has a potential application in discovering new biomarkers of diseases.展开更多
In this work,we for the first time developed a novel lithium-containing crosslinked polymeric material,a lithicone that enables excellent protection effects over lithium(Li)metal anodes.This new lithicone was synthesi...In this work,we for the first time developed a novel lithium-containing crosslinked polymeric material,a lithicone that enables excellent protection effects over lithium(Li)metal anodes.This new lithicone was synthesized via an accurately controllable molecular layer deposition(MLD)process,in which lithium tert-butoxide(LTB)and glycerol(GL)were used as precursors.The resultant LiGL lithicone was analyzed using a suite of characterizations.Furthermore,we found that the LiGL thichicone could serve as an exceptional polymeric protection film over Li metal anodes.Our experimental data revealed that the Li electrodes coated by this LiGL lithicone can achieve a superior cycling stability,accounting for an extremely long cyclability of>13,600 Listripping/plating cycles and having no failures so far in Li/Li symmetric cells at a current density of 5 mA/cm^(2)and an areal capacity of 1 mAh/cm^(2).We found that,with a sufficient protection by this LiGL coating,Li electrodes could realize long-term stable cyclability with little formation of Li dendrites and solid electrolyte interphase.This novel LiGL represents a facile and effective solution to the existing issues of Li anodes and potentially paves a technically feasible route for lithium metal batteries.展开更多
基金supported by the National Natural Science Foundation of China(Nos.52331005,52201100,52171095,and 92060113)the China Postdoctoral Science Foundation(No.2022M710346)+2 种基金Science and Technology on Advanced High Temperature Structural Materials Laboratory,China(No.6142903210207)the Fundamental Research Funds for the Central Universities,China(No.FRF-GF-20-30B)the National Key Research and Development Program of China(No.2017YFB0702902).
文摘A novel multicomponent high-Cr CoNi-based superalloy with superior comprehensive performance was prepared,and the evaluation of its high-temperature microstructural stability,oxidation resistance,and mechanical properties was conducted mainly using its cast polycrystalline alloy.The results disclosed that the morphology of theγ′phase remained stable,and the coarsening rate was slow during the long-term aging at 900–1000℃.The activation energy forγ′precipitate coarsening of alloy 9CoNi-Cr was(402±51)kJ/mol,which is higher compared with those of CMSX-4 and some other Ni-based and Co-based superalloys.Importantly,there was no indica-tion of the formation of topologically close-packed phases during this process.All these factors demonstrated the superior microstructural stability of the alloy.The mass gain of alloy 9CoNi-Cr was 0.6 mg/cm^(2) after oxidation at 1000℃ for 100 h,and the oxidation resistance was comparable to advanced Ni-based superalloys CMSX-4,which can be attributed to the formation of a continuous Al_(2)O_(3) protective layer.Moreover,the compressive yield strength of this cast polycrystalline alloy at high temperatures is clearly higher than that of the conventional Ni-based cast superalloy and the compressive minimum creep rate at 950℃ is comparable to that of the conventional Ni-based cast superalloy,demonstrating the alloy’s good mechanical properties at high temperature.This is partially because high Cr is bene-ficial in improving theγandγ′phase strengths of alloy 9CoNi-Cr.
基金supported by the National Science Foundation under Grants CMMI-1563227 and OIA-1457888。
文摘Shallow Hilbert curve patterns with easily programmable texture density were selected for laser texturing of stainless steel substrates.Two different texture path segment lengths(12 and 24 μm)and four different laser power percentages(5%,10%,15%,and 20%)were investigated.The textured and smooth substrates were coated with thin polydopamine/polytetrafluoroethylene(PDA/PTFE)coatings for tribological property assessment.The effects of texture density(texture area coverage)and laser power on the durability and friction of the coated surfaces were studied.Laser texturing the substrates improved the coating durability up to 25 times,reduced the friction coefficient,and prevented coating global delamination.The textures fabricated with a laser power of 15%and a texture path segment length of 12 μm yielded the best coating durability.The textures provided the interlocking for the PTFE coating and thus prevented its global delamination.Furthermore,the PTFE inside the texture grooves replenished the solid lubricant worn away in the wear track and prolonged the coating wear life.
基金project was supported by Health and Family Planning Commission of Chongqing Medical Research Project(No.2016ZDXM008)the outstanding young nurses in Second Hospital Affiliated to Chongqing Medical University(No.201707)Hospital Research and Construction Project of Chinese Medical Doctor Association(No.201522)
文摘Hemodialysis is the main alternative therapy for patients with end-stage renal disease;most of the hemodialysis centers in China are not designed together with the inpatient ward.During the hospitalization period,hemodialysis patients often move back and forth between wards and hemodialysis rooms because of the treatment needed.Hemodialysis patients are a special group of hospitalized patients,most of them are elderly patients.The overall basic diseases of the patients vary very much,and the cause of the disease is complex.Moreover,the chronic inflammation progresses slowly,and immune function declines.Some of the patient are seriously ill or even hav organ failure.All these factors affect the patients in general.Therefore,the transfer safety of patients during hospitalization is facing great challenges.The researchers reviewed the status of transshipment research in Chinese hemodialysis patients and laid the foundation for the research and development of related handover tools and perfect handover mode in the future.
基金Supported by the National Natural Science Foundation of China(Grant Nos.12074154,11904142 and 11722433)the Science and Technology Project of Xuzhou(Grant No.KC19010)+1 种基金the Six Talent Peaks Project and the 333 High-Level Talents Project of Jiangsu Provincethe Natural Science Research Projects of Colleges and Universities in Jiangsu Province(Grant No.19KJB140001)。
文摘Considering that pressure-induced formation of short,strong covalent bonds in light-element compounds can produce superhard materials,we employ structure searching and first-principles calculations to predict a new class of boron nitrides with a stoichiometry of BN_(2),which are stable relative to alpha-B and alpha-N_(2) at ambient pressure.At ambient pressure,the most stable phase has a layered structure(h-BN_(2)) containing hexagonal BN layers between which there are intercalated N_(2) molecules.At 25 GPa,a three-dimensional P4_(2)/mmc structure with single N-N bonds becomes the most stable.Dynamical,thermal,and mechanical stability calculations reveal that this structure can be recovered under ambient conditions.Its calculated stress-strain relations demonstrate an intrinsic superhard nature with an estimated Vickers hardness of ~43 GPa.This structure has a potentially high energy density of ~4.19 kJ/g.
基金Supported by National Natural Science Foundation of China(81874453)Natural Science Foundation of Guangxi Zhuang Autonomous Region(2020JJB140540)+5 种基金Innovation Team of Clinical Medicine Research and Application of Zhuang Medical Toxicities(04B22058A3)Guangxi Clinical Research Center for Encephalopathy of Traditional Chinese Medicine(AD20238028)The Second Batch of"Qihuang Project"High-level Talent Team Cultivation Project of Guangxi University of Traditional Chinese Medicine(2021008)Chinese Medicine Self-financing Project of Traditional Chinese Medicine Administration of Guangxi Zhuang Autonomous Region(GXZYZ20210350)Graduate Education Innovation Program of Guangxi University of Traditional Chinese Medicine(YCBZ2021076)Hospital-level Project of Guangxi International Zhuang Medical Hospital(GZ2021007)。
文摘[Objectives]The paper was to investigate the clinical effect of Fuyang prescription in the treatment of yang deficiency syndrome in the convalescent stage of ischemic stroke(IS)and its mechanism of action.[Methods]A total of 50 patients with yang deficiency syndrome in the convalescent stage of IS were randomly divided into treatment group and control group,with 25 patients in each group.The patients in the treatment group were given basic treatment combined with Fuyang prescription,and those in the control group were given basic treatment combined with Buyang Huanwu decoction;the course of treatment was 28 d for both groups.The activities of daily living(ADL)score,National Institutes of Health Stroke Scale(NIHSS)score,quality of life score,TCM syndrome score,and safety in both groups were observed before treatment and at 14 and 28 d post treatment,and their clinical outcome was evaluated.[Results]There was a significant difference in overall response rate between the treatment group and the control group[92.00%(23/25)vs 76.00%(19/25),P<0.05].After treatment,both groups had significant changes in ADL score,NIHSS score,quality of life score,and TCM syndrome score,and there were significant differences in these indices between the two groups at the same time point after treatment(P<0.05 or P<0.01).There were no significant changes in routine blood,routine stool,routine urine,and liver/renal function in either group after treatment.[Conclusions]Fuyang prescription has a marked clinical effect in the treatment of yang deficiency syndrome in the convalescent stage of IS,with significantly better clinical effect than Buyang Huanwu decoction,and it provides clinical evidence for the traditional Chinese medicine theory of yang supporting in the treatment of IS in the convalescent stage.
基金This work was supported by the National Natural Science Foundation of China(Grant No.21776067)the Outstanding Youth Foundation of Hunan Province(Grant No.2020JJ2014)+1 种基金the Natural Science Foundation of Hunan Province(Grant Nos.2022JJ30264,2020JJ5159)the Scientific Research Fund of Hunan Provincial Education Department(Grant Nos.20C0803,21B0476).
文摘The industrial application of nano-photocatalysts in wastewater treatment has been severely restricted for a long time due to their difficult separation,poor reusability,and low efficiency.In this work,a facile strategy was proposed to enhance the photocatalytic activity and recovery performance of Ag@AgCl nanocatalysts.Biological veins(Bio-veins)with a unique 3D porous construction were used as carriers for the in-situ growth of Ag@AgCl nanoparticles.Scanning electron microscopy results showed that the Ag@AgCl nanoparticles were uniformly loaded on the surface and interior of the Bio-veins,and the size of the Ag@AgCl nanoparticles immobilized on the Bio-veins(50–300 nm)was significantly smaller than Ag@AgCl obtained by the co-precipitation method(1–3μm).The Bio-veins played a vital role in the photocatalysis reaction system.The degradation efficiency of the Ag@AgCl/Bio-veins(CI4)was up to 3.50 times as high as pure Ag@AgCl.Furthermore,the composites also exhibited excellent recyclability and stability under both visible and solar light.This work provided a suitable strategy for nano-photocatalysts for practical application and may also offer new possibilities for the high-value utilization of biomass materials.
基金This material is based on work supported by the US National Science Foundation under Grant Nos.CMMI-0600642 and CMMI-0645040.
文摘A novel way of producing superhydrophobic surfaces by applying a self-assembled monolayer(SAM)to silicon micro/nano-textured surfaces is presented in this paper.The micro/nano-textured surfaces on silicon substrates were generated by the aluminum-induced crystallization(AIC)of amorphous silicon(a-Si)technique.Octadecyltrichlorosilane(OTS)SAMs were then applied to the textured surfaces by dip coating.The topography and wetting properties of the resulting surfaces were characterized using scanning electron microscopy(SEM)and a video-based contact angle measurement system.The results show that by introducing OTS SAMs on the silicon micro/nano-textured surfaces,superhydrophobic surfaces with water contact angles(WCAs)of 155°were obtained,as compared to the WCAs of OTS-modified smooth silicon surfaces of about 112°.Surface topography was found to directly influence the WCA as predicted by the Cassie-Baxter model.
基金supported by the National Basic Research Program of China(2012CB933301)the Key Discipline Construction Project of Pudong Health Bureau of Shanghai(PWZx2014-02)+1 种基金the Sci-tech Support Plan of Jiangsu Province(BE2014719)the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Herein, a multiwalled carbon nanotubes(MWNT)-based colorimetric probe was designed to discover and monitor the level of apolipoprotein-L1(Apo L1) in lumbar disc herniation(LDH) patients. Apo L1 could be easily found in human serum of the LDH group, but not obviously expressed in the normal control group(Ctrl), spine spondylolisthesis(SSP) group, spinal fracture(SFR) group, and spine scoliosis(SSC) group. Furthermore, the as-prepared MWNT-based probe was also used to track the recovery of LDH patients who have successful surgery operation. The P value of early diagnosis and recovery monitoring was <0.001 and >0.05 for the proposed method and a conventional enzyme-linked immunosorbent assay(ELISA), respectively, suggesting this detection strategy had significant differences compared with the traditional ELISA. All experimental results showed that Apo L1 might be a potential biomarker for early diagnosis of LDH. This proposed detection strategy has a potential application in discovering new biomarkers of diseases.
基金the California State University Northridge and financial support from Cottrell Scholar Award(Award#26829)by Research Corporation for Science Advancement(RCSA)This research used resources of the Advanced Photon Source,a U.S.Department of Energy(DOE)Office of Science User Facility,operated for the DOE Office of Science by Argonne National Laboratory under Contract No.DE-AC02-06CH11357.
文摘In this work,we for the first time developed a novel lithium-containing crosslinked polymeric material,a lithicone that enables excellent protection effects over lithium(Li)metal anodes.This new lithicone was synthesized via an accurately controllable molecular layer deposition(MLD)process,in which lithium tert-butoxide(LTB)and glycerol(GL)were used as precursors.The resultant LiGL lithicone was analyzed using a suite of characterizations.Furthermore,we found that the LiGL thichicone could serve as an exceptional polymeric protection film over Li metal anodes.Our experimental data revealed that the Li electrodes coated by this LiGL lithicone can achieve a superior cycling stability,accounting for an extremely long cyclability of>13,600 Listripping/plating cycles and having no failures so far in Li/Li symmetric cells at a current density of 5 mA/cm^(2)and an areal capacity of 1 mAh/cm^(2).We found that,with a sufficient protection by this LiGL coating,Li electrodes could realize long-term stable cyclability with little formation of Li dendrites and solid electrolyte interphase.This novel LiGL represents a facile and effective solution to the existing issues of Li anodes and potentially paves a technically feasible route for lithium metal batteries.
