Various functionalized asymmetrical biaryls can be synthesized in high to excellent yields via coupling reaction of aryl iodides or bromides with NaBPh4 catalyzed by MCM-41-supported sulfur palladium（0） complex. Thi...Various functionalized asymmetrical biaryls can be synthesized in high to excellent yields via coupling reaction of aryl iodides or bromides with NaBPh4 catalyzed by MCM-41-supported sulfur palladium（0） complex. This palladium complex can be easily recovered and reused many times without loss of activity.展开更多
Arylation of acrylamide and acrylonitrile were carried out with various arenediazonium tetrafluoroborates in the presence of a catalytic amount of Pd(OAc)(2) in ethanol and a variety of substituted (E)-cinnamamides an...Arylation of acrylamide and acrylonitrile were carried out with various arenediazonium tetrafluoroborates in the presence of a catalytic amount of Pd(OAc)(2) in ethanol and a variety of substituted (E)-cinnamamides and (E)-cinnamonitriles were obtained in high yields under mild reaction conditions.展开更多
Z)-a-Selanyl alkenyl Grignard reagents 2 were prepared conveniently by treatment of a-bromovinylselenides 1 with magnesium filings in THF. Intermediates 2 were reacted with alkyl iodides in the presence of CuI or Pd(...Z)-a-Selanyl alkenyl Grignard reagents 2 were prepared conveniently by treatment of a-bromovinylselenides 1 with magnesium filings in THF. Intermediates 2 were reacted with alkyl iodides in the presence of CuI or Pd(PPh3)4 to afford (Z)-1,2-disubstituted vinylselenides 3, which were cross-coupled with Grignard reagents in the presence of (PPh3)2NiCl2 to give trisubstituted alkenes 4 stereoselectively in good yields.展开更多
基金National Natural Science Foundation of China （Project 20462002） Natural Science Foundation of Jiangxi Province （Project 0420015） for financial support.
文摘Various functionalized asymmetrical biaryls can be synthesized in high to excellent yields via coupling reaction of aryl iodides or bromides with NaBPh4 catalyzed by MCM-41-supported sulfur palladium（0） complex. This palladium complex can be easily recovered and reused many times without loss of activity.
基金This work was supported by the Natural Science Foundation of Jiangxi Province.
文摘Arylation of acrylamide and acrylonitrile were carried out with various arenediazonium tetrafluoroborates in the presence of a catalytic amount of Pd(OAc)(2) in ethanol and a variety of substituted (E)-cinnamamides and (E)-cinnamonitriles were obtained in high yields under mild reaction conditions.
文摘Z)-a-Selanyl alkenyl Grignard reagents 2 were prepared conveniently by treatment of a-bromovinylselenides 1 with magnesium filings in THF. Intermediates 2 were reacted with alkyl iodides in the presence of CuI or Pd(PPh3)4 to afford (Z)-1,2-disubstituted vinylselenides 3, which were cross-coupled with Grignard reagents in the presence of (PPh3)2NiCl2 to give trisubstituted alkenes 4 stereoselectively in good yields.
