Statistics of states generated by quantum-scissors device

Generating desired states is a prerequisite in quantum information. Some desired states can be generated by a quantum-scissors device(QSD). We present a detailed analysis of the properties of the generated states, including average photon numbers and intensity gains. The theoretical analysis shows that there is a nondeterministic amplification in terms of the average photon number under the condition that the average photon number of the input state is less than 1. In contrast to the input states, the generated states show the nonclassical property described by the negativity of the Wigner function. Furthermore, we generalize the QSD to truncate arbitrary photon number terms of the input states, which may be useful in high-dimensional quantum information processing.

The safety of radium-223 combined with new-generation hormonal agents in bone metastatic castration-resistant prostate cancer: a systematic review and network meta-analysis

Patients with bone metastatic castration-resistant prostate cancer (mCRPC) might benefit from radium-223 (^(223)Ra) combined withnew-generation hormonal agents (NHAs) in terms of survival and quality of life (QoL). However, the safety of combination therapiesremains unclear. Therefore, we aimed to perform a network meta-analysis by reviewing the literature about the combination of^(223)Ra with abiraterone acetate plus prednisone (AAP) or enzalutamide and to evaluate the safety of combination therapy in bonemCRPC patients. Ultimately, ten studies (2835 patients) were selected, including four randomized controlled trials (RCTs), fiveretrospective cohort studies, and one single-arm study. Overall, there was no difference in the incidence of fracture between the^(223)Ra+NHA combination group and the ^(223)Ra monotherapy group (odds ratio [OR]: 1.46, 95% confidence interval [CI]: 0.91–2.34,P = 0.66), but the incidences in both the ^(223)Ra+NHA combination group (OR: 3.22, 95% CI: 2.24–4.63, P < 0.01) and the ^(223)Ramonotherapy group (OR: 2.24, 95% CI: 1.23–4.08, P < 0.01) were higher than that in the NHA monotherapy group. However, inthe meta-analysis involving only RCTs, there was no difference between the ^(223)Ra monotherapy group and the NHA monotherapygroup (OR: 1.14, 95% CI: 0.22–5.95, P = 0.88), while the difference between the ^(223)Ra+NHA combination group and the NHAmonotherapy group remained significant (OR: 3.22, 95% CI: 2.24–4.63, P < 0.01). Symptomatic skeletal events (SSEs), SSE-freesurvival (SSE-FS), all grades of common adverse events (AEs), and ≥grade 3 AEs among all groups did not show any significantdifference. Our results indicate that the combination of ^(223)Ra with NHAs was well tolerated in bone mCRPC patients compared to ^(223)Ra monotherapy, even though the incidence of fracture was higher in patients who received ^(223)Ra than that among those whoreceived NHA monotherapy. More evidence is needed to explore the safety and efficiency of ^(223)Ra combination therapies.

A Position and Torque Switching Control Method for Robot Collision Safety

With the increasing number of human-robot interaction applications, robot control characteristics and their effects on safety as well as performance should be taken account into the robot control system. In this paper, a position and torque switching con- trol method was proposed to improve the robot safety and performance, when robots and humans work in the same space. The switch- ing control method includes two modes, the position control mode using a proportion-integral （PI） algorithm, and the torque control mode using sliding mode control （SMC） algorithm for eliminating swing. Under the normal condition, the robot works in position con- trol mode for trajectory tracking with quick response. Once the robot and human collide, the robot will switch to torque control mode immediately, and the impact force will be restricted within a safe range. When the robot and human detach, the robot will resume to po- sition control mode automatically. Moreover, for a better performance, the joint torque is detected fl＇om direct-current （DC） motor＇s cur- rent rather than the torque sensor. The experiment results show that the proposed approach is effective and feasible.