Objective: To probe the potential use of duodenosco- py in the diagnosis and treatment of acute gallstone pancreatitis (GP). Methods: Fourty-five patients with acute GP were randomly divided into endoscopic retrograde...Objective: To probe the potential use of duodenosco- py in the diagnosis and treatment of acute gallstone pancreatitis (GP). Methods: Fourty-five patients with acute GP were randomly divided into endoscopic retrograde cholan- giopancreatography (ERCP) group (n=20) and non-ERCP group (n=25). Each group was subdivi- ded into mild and severe groups according to A- PACHE Ⅱ scores. They were given supportive treat- ment combined with traditional Chinese medicine. The patients in the ERCP group received ERCP within 24 hours after admission. If there were stones in the common bile duct with stenosis of the inferior extremity or ampulla, endoscopic sphincterotomy (ES) was performed to extract the stones by basket. If no calculi were identified or multiple stones were large, endoscopic naso-biliary drainage (ENBD) was carried out. Results: The incidence of complication, length of hospitalization and cost were markedly lower in pa- tients with severe acute GP in the ERCP group than those in the non-ERCP group (P<0.05), in contrast to the 2 mild subgroups of the ERCP and non-ERCP groups (P>0.05). Conclusion: It is feasible, effective and safe to apply duodenoseopy in the treatment of severe acute GP.展开更多
文摘Objective: To probe the potential use of duodenosco- py in the diagnosis and treatment of acute gallstone pancreatitis (GP). Methods: Fourty-five patients with acute GP were randomly divided into endoscopic retrograde cholan- giopancreatography (ERCP) group (n=20) and non-ERCP group (n=25). Each group was subdivi- ded into mild and severe groups according to A- PACHE Ⅱ scores. They were given supportive treat- ment combined with traditional Chinese medicine. The patients in the ERCP group received ERCP within 24 hours after admission. If there were stones in the common bile duct with stenosis of the inferior extremity or ampulla, endoscopic sphincterotomy (ES) was performed to extract the stones by basket. If no calculi were identified or multiple stones were large, endoscopic naso-biliary drainage (ENBD) was carried out. Results: The incidence of complication, length of hospitalization and cost were markedly lower in pa- tients with severe acute GP in the ERCP group than those in the non-ERCP group (P<0.05), in contrast to the 2 mild subgroups of the ERCP and non-ERCP groups (P>0.05). Conclusion: It is feasible, effective and safe to apply duodenoseopy in the treatment of severe acute GP.
