The C–Ge cross-coupling offers a promising approach for the precise synthesis of organogermanes. However, the current methods are primarily effective in the germylation of organo(pseudo)halides. This work demonstrate...The C–Ge cross-coupling offers a promising approach for the precise synthesis of organogermanes. However, the current methods are primarily effective in the germylation of organo(pseudo)halides. This work demonstrates the possibility of transferring low-cost and easily available ester groups into organogermanes through the cleavage of stable C–O bonds. Primary,secondary, and even tertiary benzylic pivalates were coupled well with chlorogermanes. The reactions proceed under mild conditions. The scalability of this reaction and derivatization of the formed benzylgermanes are demonstrated.展开更多
基金supported by the National Natural Science Foundation of China (22071084, 22271127)the Fundamental Research Funds for the Central Universities (lzujbky-2022-ey01)。
文摘The C–Ge cross-coupling offers a promising approach for the precise synthesis of organogermanes. However, the current methods are primarily effective in the germylation of organo(pseudo)halides. This work demonstrates the possibility of transferring low-cost and easily available ester groups into organogermanes through the cleavage of stable C–O bonds. Primary,secondary, and even tertiary benzylic pivalates were coupled well with chlorogermanes. The reactions proceed under mild conditions. The scalability of this reaction and derivatization of the formed benzylgermanes are demonstrated.
