A large amount of cutting heat is produced during the heavy cutting process,and insert life is restricted by the effect of thermal load. The thermal load experiment of cemented carbide SCS,WF and YT15 is carried out,a...A large amount of cutting heat is produced during the heavy cutting process,and insert life is restricted by the effect of thermal load. The thermal load experiment of cemented carbide SCS,WF and YT15 is carried out,and the results show that the bending strength and fracture toughness of cemented carbide material decrease obviously under cyclic thermal load,while in the cooling process,the material mechanical property changes worse suddenly. The high-temperature mechanical property of SCS is the most stable,and that of YT15is the worst. Further,a relation model among cutting temperature,cutting parameters and insert life is established. Finally,the measures to improve heavy cemented carbide inserts life are summarized from the aspects of cutting parameters selection,insert optimization design and TiCN,A12O3,TiN complex insert coating. The research results are expected to provide support and reference for heavy cutting technology and insert technology.展开更多
The skin constitutes the primary barrier between the human body and the external environment.The skin microbiome plays an important role in the microecosystem on the skin surface and mediates multiple facets of the sk...The skin constitutes the primary barrier between the human body and the external environment.The skin microbiome plays an important role in the microecosystem on the skin surface and mediates multiple facets of the skin barrier function,including physical,chemical,microbial,and immune barriers.In this review,we discuss the host-microbiota interactions in barrier maintenance and disruption,implications for skin disorders such as atopic dermatitis,psoriasis,and rosacea,and the latest strategies for targeting the skin microbiota to improve the skin barrier.展开更多
Harvesting the low-grade(<100°C)solar thermal energy with ionic heat-to-electricity conversion shows great promise but low efficiencies due to the challenges encountered in regulating ionic thermophoretic mobi...Harvesting the low-grade(<100°C)solar thermal energy with ionic heat-to-electricity conversion shows great promise but low efficiencies due to the challenges encountered in regulating ionic thermophoretic mobilities.Here,we used nanochannels to regulate thermal-driven ion transport properties and described a solar thermoelectric nanofluidic device(STEND).展开更多
基金Projects(51471064,51301054)supported of the National Natural Science Foundation of ChinaProject(1253-NCET-009)supported by the Program for New Century Excellent Talents,China+1 种基金Project(1251G022)supported by Program for Youth Academic Backbone in Heilongjiang Provincial University,ChinaProject(12541138)supported by Scientific Research Fund of Heilongjiang Provincial Education Department,China
基金Sponsored by the National Natural Science Foundation of China(Grant No.51205095)Support Program for Key Youth(Grant No.1154G39)
文摘A large amount of cutting heat is produced during the heavy cutting process,and insert life is restricted by the effect of thermal load. The thermal load experiment of cemented carbide SCS,WF and YT15 is carried out,and the results show that the bending strength and fracture toughness of cemented carbide material decrease obviously under cyclic thermal load,while in the cooling process,the material mechanical property changes worse suddenly. The high-temperature mechanical property of SCS is the most stable,and that of YT15is the worst. Further,a relation model among cutting temperature,cutting parameters and insert life is established. Finally,the measures to improve heavy cemented carbide inserts life are summarized from the aspects of cutting parameters selection,insert optimization design and TiCN,A12O3,TiN complex insert coating. The research results are expected to provide support and reference for heavy cutting technology and insert technology.
基金supported by the Nanjing Incubation Program for National Clinical Research Center(No.2019060001)Key Project of Social Development in Jiangsu Province(No.BE2020632)+2 种基金National Natural Science Foundation of China(Nos.82073446 and 82103735)CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2021-I2M-1-059)National Key R&D Program of China(No.2022YFC3601800)
文摘The skin constitutes the primary barrier between the human body and the external environment.The skin microbiome plays an important role in the microecosystem on the skin surface and mediates multiple facets of the skin barrier function,including physical,chemical,microbial,and immune barriers.In this review,we discuss the host-microbiota interactions in barrier maintenance and disruption,implications for skin disorders such as atopic dermatitis,psoriasis,and rosacea,and the latest strategies for targeting the skin microbiota to improve the skin barrier.
基金supported by the National Natural Science Foundation of China(nos.21635004,21775066,and 21974058).
文摘Harvesting the low-grade(<100°C)solar thermal energy with ionic heat-to-electricity conversion shows great promise but low efficiencies due to the challenges encountered in regulating ionic thermophoretic mobilities.Here,we used nanochannels to regulate thermal-driven ion transport properties and described a solar thermoelectric nanofluidic device(STEND).
